Saturday
1:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
3:45 pm - 4:30 pm
Keynote Session: Developmental Control of Polarity
Discussion Leader: Songeun Kim (University of Wisconsin-Madison, United States)
3:45 pm - 4:20 pm
Marie-Hélène Verlhac (CIRB, Collège de France, Paris, France)
"Aberrant Cortex Contractions Impact Mammalian Oocyte Quality"
4:20 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Mechanochemical Influence on Polarity Axes
Discussion Leader: Bryce LaFoya (University of Oregon, United States)
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 7:55 pm
Henry De Belly (UCSF, United States)
"Long Range Mutual Facilitation Complements Local Inhibition to Globally Pattern Rac and Rho During Cell Migration"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 8:15 pm
Evgeniya Pukhovaya (Wageningen University, The Netherlands)
"Discovering Mechanisms of Polar Protein Localization in Plants"
8:15 pm - 8:20 pm
Discussion
8:20 pm - 8:35 pm
Ruben Tesoro Moreno (European Molecular Biology Laboratory, Germany)
"The Missing Link of Surface Mechanics: Protein Caging Triggers Symmetry Breaking"
8:35 pm - 8:40 pm
Discussion
8:40 pm - 8:55 pm
Ana Maria Carmo (University of Toronto, Canada)
"Cofilin Promotes Actomyosin Turnover to Drive Rapid Wound Healing"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:15 pm
Alyssa Quiogue (University of Oregon, United States)
"Microtubules Oppose Cortical Actomyosin-Driven Membrane Ingression During C. Elegans Meiosis I Polar Body Extrusion"
9:15 pm - 9:20 pm
Discussion
9:20 pm - 9:30 pm
General Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Polarity Signal Integration in Development and Regeneration
Discussion Leader: Vikrant Mahajan (Johns Hopkins University, United States)
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:20 am
Jia Chen (Gurdon Institute, University of Cambridge, United Kingdom)
"Unknown Basal Receptor(s), Not Integrins, Determine Epithelial Polarity in the Fly Midgut"
9:20 am - 9:25 am
Discussion
9:25 am - 9:40 am
Sheng-Ping Hsu (Cell and Molecular Biology in University of Texas at Austin, United States)
"Multivalent Assembly of PAR-3-aPKC Complexes Establishes Cell Polarity in C. Elegans Zygotes"
9:40 am - 9:45 am
Discussion
9:45 am - 10:00 am
Amelie Raz (Whitehead Institute, United States)
"Combinatorial Signaling Balances Maintenance and Renewal of Germline Stem Cell Fate"
10:00 am - 10:05 am
Discussion
10:05 am - 10:20 am
Parijat Sil (Princeton University, United States)
"Defining the Role of Dishevelled in Planar Cell Polarity Establishment in the Mammalian Embryonic Epidermis"
10:20 am - 10:25 am
Discussion
10:25 am - 10:40 am
Aishwarya Venkataravi (Vanderbilt University, United States)
"Unraveling the Role of Polarity Remodeling During Cell Intercalation"
10:40 am - 10:45 am
Discussion
10:45 am - 11:00 am
General Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Precocious Polarity and Modeling Disease States
Discussion Leader: Nydia Tejeda Munoz (University of Oklahoma Health Sciences Center, United States)
1:30 pm - 1:45 pm
Ankita Jha (National Institutes of Health, United States)
"Receptor Corralling Establishes Front-Rear Polarity During Bleb-Based Migration Under Confinement"
1:45 pm - 1:50 pm
Discussion
1:50 pm - 2:05 pm
Gerald Lerchbnaumer (University of Toronto, Canada)
"Post Translational Regulation of E-Cadherin Guides Developmental EMT"
2:05 pm - 2:10 pm
Discussion
2:10 pm - 2:25 pm
Mariyah Saiduddin (Whitehead Institute, United States)
"Spatiotemporal Control of Membrane Addition Allows for Primordial Germ Cell Formation"
2:25 pm - 2:30 pm
Discussion
2:30 pm - 3:00 pm
Evaluation Period
Complete the GRS Evaluation Forms; Election of Future Chair(s)
3:00 pm
Seminar Concludes