Membrane Proteins: From Structure to Disease

June 9 - 10, 2018

Chairs

and

Grand Summit Hotel at Sunday River

97 Summit Road

Newry, Maine, United States

Venue and Travel Information

Conference Description

The Gordon Research Seminar on Membrane Transport Proteins is a unique forum for graduate students, post-docs, and other scientists with comparable levels of experience and education to present and exchange new data and cutting edge ideas.

During the GRS, young scientists from all around the world will present their work centered around membrane transport protein biology. Scientific sessions will start with presentations on structure-function relationships and transition to physiology and disease. The seminar will also feature two scientific poster sessions and a Young Scientists Career panel during which invited speakers from academia, industry and scientific publishing will deliver talks and discuss their career paths with the attendees.

Related Meeting

This GRS will be held in conjunction with the "Membrane Transport Proteins" Gordon Research Conference (GRC). Those interested in attending both meetings must submit an application for the GRC in addition to an application for the GRS. Refer to the associated GRC program page for more information.

Conference Program

Saturday
2:00 pm - 5:00 pm	Arrival and Check-in
3:30 pm - 3:45 pm	Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm	Keynote Session: High-Speed Atomic Force Microscopy: A Revolutionary New Technique to Study Membrane Proteins Discussion Leader:
3:45 pm - 4:20 pm	"High-Speed Atomic Force Microscopy: Taking Movies of Single Membrane Proteins at Work! ...and How I Got There"
4:20 pm - 4:30 pm	Discussion
4:30 pm - 6:00 pm	Poster Session
6:00 pm - 7:00 pm	Dinner
7:30 pm - 9:30 pm	Membrane Transport Proteins: Structure and Function Discussion Leader:
7:30 pm - 7:45 pm	"Substrate Ambiguity for the Sodium Sialic Acid Symporter from Staphylococcus aureus"
7:45 pm - 7:50 pm	Discussion
7:50 pm - 8:05 pm	"Structure-Function of Human ABCG2: Evidence for a Novel Drug Transport Mechanism"
8:05 pm - 8:10 pm	Discussion
8:10 pm - 8:25 pm	"A Conserved Tryptophan Regulates the Conformational Equilibrium in Neurotransmitter:Sodium Symporters"
8:25 pm - 8:30 pm	Discussion
8:30 pm - 8:45 pm	"Characterization of the Structure-Function Relationship of the Na-K-Cl Importer NKCC1"
8:45 pm - 8:50 pm	Discussion
8:50 pm - 9:05 pm	"Ion- and Dopamine-Induced Conformational Dynamics of the Dopamine Transporter"
9:05 pm - 9:10 pm	Discussion
9:10 pm - 9:25 pm	"Overexpression and Purification of Human Dopamine Transporter"
9:25 pm - 9:30 pm	Discussion
Sunday
7:30 am - 8:30 am	Breakfast
9:00 am - 11:00 am	Translational Membrane Protein Biology Discussion Leader:
9:00 am - 9:15 am	"Phase-1 Metabolites of Mephedrone Reveal Chiral Selectivity Towards the Serotonin Transporter"
9:15 am - 9:20 am	Discussion
9:20 am - 9:35 am	"Label-Free Detection of Transporter Inhibitors' Efficacy in Living Cells"
9:35 am - 9:40 am	Discussion
9:40 am - 9:55 am	"Making a Better Sodium/Iodide Symporter: Unraveling the Mysteries of NIS Substrate Affinity and Promiscuity"
9:55 am - 10:00 am	Discussion
10:00 am - 10:15 am	"Implications of Phosphopantetheine (P-PantSH) Membrane Transport in CoA Targeted Drug Development"
10:15 am - 10:20 am	Discussion
10:20 am - 10:35 am	"Interaction Proteomics of Native KCC2 Reveal Key Components of Excitation-Inhibition Balance in the Central Nervous System (CNS)"
10:35 am - 10:40 am	Discussion
10:40 am - 10:55 am	"Sex Differences in Chronic Inflammatory Disease"
10:55 am - 11:00 am	Discussion
11:00 am - 12:30 pm	Poster Session Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm	Lunch
1:30 pm - 2:30 pm	Mentorship Component: Young Scientist Career Paths Representatives from academia, industry and scientific publishing will give an overview of their professional journeys and the current landscape for young scientists inside and outside the classical academic setting. Discussion Leader:
1:30 pm - 1:45 pm	"From Making Toxins, to Avoiding Them: A Journey Towards Drug Discovery"
1:45 pm - 1:50 pm	Discussion
1:50 pm - 2:05 pm	"Taking Ownership: Build the Mentorship You Need for Your Career to Succeed"
2:05 pm - 2:10 pm	Discussion
2:10 pm - 2:25 pm	"Navigating a Postdoc: When You Stop Trying to Figure It All Out"
2:25 pm - 2:30 pm	Discussion
2:30 pm - 3:00 pm	Evaluation Period Fill in GRS Evaluation Forms
3:00 pm	Seminar Concludes

Contributors

Funding for this conference was made possible (in part) by National Institute Of Neurological Disorders And Stroke of the National Institutes of Health under Award Number R13NS106931.The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention by trade names, commercial practices, or organizations imply endorsement by the U.S. Government.

Conference Links

Conference History Membrane Transport Proteins

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