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Genetic Toxicology
Gordon Research Conference

Conference Information

Status

Inactive

Initial Year

1981

Discipline

Biological

Categories

Meeting Cycle

24 Months

Conference Description

A decade ago, the study of the impact of DNA damage was seen as a compartmentalised area of cellular research. It is now appreciated to lie at the centre of an array of cellular responses of crucial importance to human health. Genetic toxicology represents a study of the genetic damage that a cell can incur, the agents that induce such damage, the damage response mechanisms available to cells and organisms, and the potential consequences of such damage. Genotoxic agents are abundant in the environment and are also induced endogenously. The consequences of such damage can include carcinogenesis and teratogenesis. An understanding of genetic toxicology is essential to carry out risk evaluations of the impact of genotoxic agents and to assess how individual genetic differences influence the response to genotoxic damage. In recent years it has been increasingly recognised that maintaining genomic stability is crucial to human health and that failure of the damage response mechanisms underlies many, if not all, cancer incidence. The importance of these mechanisms is also underscored by their remarkable conservation between species, allowing the study of simple organisms to provide significant input into our understanding of the underlying mechanisms.

The Genetic Toxicology Gordon Research Conferences are biannual and the emphasis of the meetings evolves rapidly. Evaluating the nature of genotoxic chemicals lay at the centre of the early conferences. Over the years, the emphasis has moved to understanding how cells and organisms respond to the different forms of genotoxic damage incurred. By understanding these mechanisms, the risk to humans can be more rationally assessed and evaluated. Most recently, the format of the meetings have aimed to facilitate input from the range of disciplines that can provide insight into the field.

What is a GRC? Gordon Research Conferences (GRC) are 5-day meetings that bring scientists together from around the world to present and discuss unpublished research with other leaders in their field.

Meeting History

YearMeeting NameDatesConference SiteChair(s)
2011 Genetic Toxicology Jul 10-15 Renaissance Tuscany Il Ciocco Jessica A. Downs
2009 Genetic Toxicology Aug 9-14 Colby-Sawyer College Samuel H. Wilson
2007 Genetic Toxicology Jul 29 - Aug 3 Magdalen College Anthony M. Carr
2005 Genetic Toxicology Jul 31 - Aug 5 Colby-Sawyer College Bennett Van Houten
2003 Genetic Toxicology Aug 10-15 The Queen's College Penelope Jeggo
2001 Genetic Toxicology Aug 12-17 Colby-Sawyer College Thomas A. Kunkel
1999 Genetic Toxicology Aug 1-6 The Queen's College Leona D. Samson
1997 Genetic Toxicology Jun 22-27 Colby-Sawyer College Kenneth R. Tindall
1995 Genetic Toxicology Jun 11-16 Colby-Sawyer College Julian Preston
1993 Genetic Toxicology Jul 25-30 Colby-Sawyer College Sid Aaron
1991 Genetic Toxicology Jun 10-14 Colby-Sawyer College Richard J. Albertini
1989 Genetic Toxicology Jun 19-23 Colby-Sawyer College Daniel A. Casciano
1987 Genetic Toxicology Bioassays Jun 22-26 Salve Regina University William G. Thilly
1985 Genetic Toxicology Bioassays, Scientific Basis and Application of Jun 10-14 Colby-Sawyer College David F. Krahn
1983 Genetic Toxicology Bioassays, Scientific Basis and Application of Jun 27 - Jul 1 Colby-Sawyer College Ceinwen A. Schreiner
1981 Genetic Toxicology Bioassays, Scientific Basis and Application of Jun 29 - Jul 3 Colby-Sawyer College Andrew Sivak
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