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Mutagenesis
Gordon Research Conference

Conference Information

Status

Active

Initial Year

1978

Discipline

Biological

Categories

Meeting Cycle

24 Months

Conference Description

Mutations are the changes in DNA that drive evolutionary processes, and such changes occur both at the nucleotide and at the chromosomal level. Although a low level of mutagenesis is essential for the adaptation of species to an ever-changing environment, most mutations are detrimental and have negative effects on survival. The Mutagenesis Conference focuses broadly on the molecular mechanisms by which DNA replication errors and premutagenic lesions arise, on the diverse pathways that remove mutational intermediates in order to prevent their fixation, and on the checks and balances that together maintain an acceptable level of mutagenesis. While recent years have witnessed a dramatic shift in emphasis towards the more complicated eukaryotic systems that have direct relevance to human disease, basic knowledge continues to be generated using simpler microbial systems and defined biochemical systems. The experimental tools for studying mutagenesis have also broadened to include structural and cell biological techniques as well as the more traditional genetic and biochemical approaches. The Mutagenesis Conference thus attracts scientists with diverse experimental approaches and covers a wide range of topics that include replication fidelity, chemical synthesis of modified DNA, somatic hypermutation in the immune system, evolution, genetic toxicology, carcinogenesis, analysis of protein and DNA structure, and DNA repair. The Conference not only brings together established investigators to present and discuss their most recent unpublished data, but also encourages the active participation of younger scientists who are in the formative stages of their careers. The unique breadth of the Mutagenesis Conference in terms of topics and participants continues to foster the cross-fertilization of ideas and the establishment of collaborations that lead to novel discoveries.

What is a GRC? Gordon Research Conferences (GRC) are 5-day meetings that bring scientists together from around the world to present and discuss unpublished research with other leaders in their field.

Related Conference

This Gordon Research Conference (GRC) series is related to the "Mutagenesis" Gordon Research Seminar (GRS) series. Although a related GRS will typically be scheduled in conjunction with its parent GRC each time it meets, that may not always be the case. Refer to the individual meetings in the Meeting History section below for more details. For more information about the associated Gordon Research Seminar (GRS) series, click here.

What is a GRS? Gordon Research Seminars (GRS) are 2-day meetings that bring graduate students and post-docs together to discuss their cutting edge research among peers and mentors. Each GRS immediately precedes an associated Gordon Research Conference (GRC), and topics addressed at the GRS relate closely to the GRC.

Meeting History

YearMeeting NameDatesConference SiteChair(s)
2018 Mutagenesis Jun 24-29 Grand Summit Hotel at Sunday River Karlene Cimprich
2016 Mutagenesis
Mechanisms of Mutagenesis and Genome Alterations
Jun 5-10 PGA Catalunya Business and Convention Centre Simon Boulton
2014 Mutagenesis
Changes to the Genetic Landscape, from Single Nucleotides to Entire Genomes
Jun 15-20 PGA Catalunya Business and Convention Centre Robert Lahue
2012 Mutagenesis
A Delicate Balance: Cellular Mutation Pathways in Genetic Stability and Disease
Aug 19-24 Salve Regina University Bruce Demple
2010 Mutagenesis
Consequences of Mutation and Repair for Human Disease
Aug 1-6 Colby College Nancy Maizels
2008 Mutagenesis Jul 20-25 Magdalen College Roger Woodgate
2006 Mutagenesis Aug 6-11 Salve Regina University Sue Jinks-Robertson
2004 Mutagenesis Sep 12-17 The Queen's College Miroslav Radman
2002 Mutagenesis Jul 28 - Aug 2 Bates College Myron F. Goodman
2000 Mutagenesis Aug 20-25 The Queen's College Josef Jiricny
1998 Mutagenesis Jun 21-26 Plymouth State College Susan S. Wallace
1996 Mutagenesis Jun 23-28 Plymouth State College Philip C. Hanawalt
1994 Mutagenesis Jun 26 - Jul 1 Plymouth State College John M. Essigmann
1992 Mutagenesis Jun 29 - Jul 3 Plymouth State College Thomas A. Kunkel
1990 Mutagenesis Jul 9-13 Plymouth State College Graham C. Walker
1988 Mutagenesis Jun 20-24 Plymouth State College Franklin Hutchinson
1986 Mutagenesis Jun 30 - Jul 4 Plymouth State College Lawrence A. Loeb
1984 Mutagenesis Jul 2-6 Plymouth State College John W. Drake
1982 Mutagenesis, Biological & Chemical Mechanisms of Jul 5-9 New Hampton School B. Singer
1980 Mutagenesis, Biological & Chemical Mechanisms of Jul 14-18 Proctor Academy Bernard S. Strauss
1978 Environmental and Genetic Toxicology Jun 26-30 Plymouth State College Lawrence I. Grossman
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