is a ubiquitous intracellular messenger; it is an essential regulator of many cellular processes including fertilization, cell death, sensory transduction, muscle contraction, motility, exocytosis and fluid secretion. Defective Ca2+
signalling is a feature of diverse diseases (e.g. hypertension and immunodeficiencies). Since Ca2+
is widely used by cells to regulate their behaviour, there is a correspondingly diverse range of activities amongst investigators with an interest in Ca2+
signalling. Thus, this GRC provides a unique opportunity for such investigators, who might otherwise never attend the same conferences, to meet and discuss progress from many perspectives. An important feature of the programme is that it brings together investigators whose primary interests are in fundamental aspects of Ca2+
signalling with those whose interests focus primarily on the physiology or pathology of specific tissues in which Ca2+
signals play an important role. The selection of speakers and topics for the sessions reflects this diversity. For example the topics that are addressed in this conference include plasma membrane signal transduction/sensing mechanisms, intracellular calcium release, calcium entry, calcium channel regulation and structure, calcium pump function, signalling microdomains, and disease associated with calcium signalling. In addition the role of calcium signalling in the regulation of functions of specific tissues or cell such as such as muscles, exocrine gland, endothelium, kidney, neurons, etc. are also discussed in detail.
This conference takes place biennially and provides a premier forum for scientists with diverse interests in the many facets of calcium signalling to review exciting developments in this active area. It has become established policy to alternate this GRC between Europe and the USA, this policy is both popular and successful, not least in fostering international interactions and in allowing junior scientists from both continents to participate. In 2007, we will have the eighth meeting. The topics covered are of fundamental importance, widespread interest and immediate relevance to many disease states including neurodegenerative and cardiovascular diseases, aging, cancer, sensory disorders, and immunological diseases.
What is a GRC? Gordon Research Conferences (GRC) are 5-day meetings that bring scientists together from around the world to present and discuss unpublished research with other leaders in their field.
This Gordon Research Conference (GRC) series is related to the "Calcium Signalling" Gordon Research Seminar (GRS)
series. Although a related GRS will typically be scheduled in conjunction with its parent GRC each time it meets, that may not always be the case. Refer to the individual meetings in the Meeting History
section below for more details. For more information about the associated Gordon Research Seminar (GRS) series, click here
.What is a GRS? Gordon Research Seminars (GRS) are 2-day meetings that bring graduate students and post-docs together to discuss their cutting edge research among peers and mentors. Each GRS immediately precedes an associated Gordon Research Conference (GRC), and topics addressed at the GRS relate closely to the GRC.