Tissue Repair & Regeneration
After injury to adult tissues, a programmed series of biological events takes place that ideally would reconstitute the damaged part of the body. However, repair in postnatal mammals generally leads to scar formation, and in chronic phase, often to an impairment of tissue function. Most importantly, several disease conditions, such as ulceration, fibrosis, chronic obstructive pulmonary disease, colitis, and many others are associated with severe healing abnormalities, demonstrating the strong need to understand and modulate these processes. Therefore, it is of major importance to elucidate the mechanisms underlying normal and impaired tissue repair, with some attention given to the mechanisms of wound healing.
Besides the important clinical aspect, the tissue repair process is widely accepted as a diverse and relevant model system for the study of numerous and distinct cellular processes, including analysis of growth factor function, regulation of matrix deposition and degradation, cell migration, apoptosis, angiogenesis, and control of cellular homeostasis. Therefore, this field, and this conference in particular, has attracted a series of internationally highly recognized basic scientists who work on these various topics. A key goal of this conference is to shed new light onto the mechanisms underlying tissue repair processes and to highlight the commonality of repair processes among tissues and across species and links between repair, regeneration, development, and specific diseases are addressed.
Although this conference focuses on the basic science of tissue repair and regeneration, it also attracts clinicians and investigators from industry. Discussions among these different groups helps to translate and transfer the new basic science findings in tissue repair biology into novel medicines for improving wound healing/tissue repair in the clinic. Moreover, new understanding of the cells and mechanisms involved in tissue regeneration bring us closer to appropriate therapies to replace or regenerate damaged or defective tissue.
What is a GRC? Gordon Research Conferences (GRC) are 5-day meetings that bring scientists together from around the world to present and discuss unpublished research with other leaders in their field.
This Gordon Research Conference (GRC) series is related to the "Tissue Repair & Regeneration" Gordon Research Seminar (GRS)
series. Although a related GRS will typically be scheduled in conjunction with its parent GRC each time it meets, that may not always be the case. Refer to the individual meetings in the Meeting History
section below for more details. For more information about the associated Gordon Research Seminar (GRS) series, click here
.What is a GRS? Gordon Research Seminars (GRS) are 2-day meetings that bring graduate students and post-docs together to discuss their cutting edge research among peers and mentors. Each GRS immediately precedes an associated Gordon Research Conference (GRC), and topics addressed at the GRS relate closely to the GRC.