IGF & Insulin System in Physiology & Disease
The Gordon Research Conference on “Insulin-like Growth Factors in Physiology & Disease” is a fairly recent conference that was initiated in 2001 to address a field of research that is rapidly expanding and has implications for a variety of basic cellular processes and disease states. The IGF system is complex with two major IGF ligands and at least three receptors mediating ligand-induced cell proliferation, survival, differentiation, metabolism and migration in virtually every bodily system. Specific IGF binding proteins (IGFBPs) can enhance or inhibit IGF action, as well as have IGF-independent effects. This conference covers the spectrum of IGF-relevant topics from basic biology to clinical interventions, with the emphasis on timely, rapidly emerging areas in IGF physiology and pathophysiology. Major topics of the conference include gene transcription, intracellular signaling, stem cell biology, cancer targeting, diabetes, cardiovascular disease, obesity, the nervous system and aging.
What is a GRC? Gordon Research Conferences (GRC) are 5-day meetings that bring scientists together from around the world to present and discuss unpublished research with other leaders in their field.