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Pancreatic Diseases
Gordon Research Conference

Conference Information

Status

New

Initial Year

2013

Discipline

Biological

Categories

Meeting Cycle

24 Months

Conference Description

The field of pancreatic disease is wide and it combines disparate research communities of basic scientists, endocrinologists, oncologists and surgeons specializing in the cell biology, pathogenesis, diagnosis, prevention, and treatment of diabetes, cancer and pancreatitis. Pancreatic neoplasms are among the most malignant and untreatable forms of cancer. The inability of pancreatic beta cells to supply insulin in amounts adequate to meet metabolic needs is the ultimate cause of all forms of diabetes. The epidemic increase of this disease represents a major threat to human health and society. Diabetes often precedes pancreatic cancer and is thus regarded as a potential risk factor for malignancy. Chronic pancreatitis, in turn, can result in the disruption of pancreatic islets and diabetes. Lineage-tracing studies in mice are unraveling the transcriptional program and signaling pathways presiding pancreatic organogenesis and the specification of its exocrine and endocrine components. This information is being exploited to devise protocols for the differentiation of embryonic stem/induced-pluripotent stem cells into pancreatic beta cells for the regenerative therapy of diabetes. Moreover, pancreatic ductal and acinar cells are being considered as potential sources for regeneration/transdifferentiation of pancreatic beta cells.

Hence, the broad scope of this conference is to support the development of a multidisciplinary research community addressing medical, biological, chemical and pharmacological topics related to the diversity and complexity of pancreatic diseases. This long-term objective will be achieved through a series of conferences, in which the emphasis of the various topics will vary overtime depending on the most recent and promising discoveries on pancreatic biology and diseases. Progress will be further fostered through the selected invitation of highly ranked investigators from other scientific areas. Through the contribution of leading experts, we expect to identify novel concepts for the pharmacological and cell-based treatment of pancreatic diseases. To set the stage for this ambitious program, the kick-off conference of this series will deliberately cover the wide-spectrum of pancreatic diseases, with emphasis on regenerative medicine. Future topics of special interests will include, but not be restricted to: a) novel insight into the cell biology and physiology of pancreatic cells; b) signaling pathways connecting pancreatic cells to other gastrointestinal organs and the nervous system; c) the contribute of environmental agents (e.g. nutrients, pathogens and toxic agents) towards the development of pancreatic diseases; d) genetic and epigenetic susceptibility to pancreatic disorders; e) biomarkers for the prevention, early diagnosis, and personalized treatment of pancreatic diseases; f) inflammation and pancreatic diseases and autoimmune pancreatitis.

What is a GRC? Gordon Research Conferences (GRC) are 5-day meetings that bring scientists together from around the world to present and discuss unpublished research with other leaders in their field.

Meeting History

YearMeeting NameDatesConference SiteChair(s)
2017 Pancreatic Diseases
Exocrine and Endocrine Pancreas: Molecules to Human
Jun 18-23 Waterville Valley Diane M. Simeone
2015 Pancreatic Diseases
Frontiers in Pancreatic Research
Jul 19-24 Mount Holyoke College Michele Solimena
2013 Pancreatic Diseases
From Molecules to Patients
Jul 21-26 Mount Holyoke College Marco Falasca
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