SUNDAY |
2:00 pm - 9:00 pm | Arrival and check-in |
6:00 pm | Dinner |
7:30 PM | Session 1: The Hypothesis Behind Early Detection |
| Discussion Leaders:
David A. Fishman MD Northwestern University,
Sudhir Srivastava PhD NCI |
7:45 PM- 9:00 PM | Principal Speaker(s): |
| Lee Hartwell, Ph.D., Fred Hutchinson Cancer Research Center
The Accumulation of Genetic Variation and Expression of Natural Genetic Variation |
| Peter Jones, MD USC Norris Comprehensive Cancer Institute, CA
Future Visions for Cancer Detection |
| Philip Needleman, Ph.D., Pharmacia Corporation
COX-2: From Inflammation to Cancer |
9:30 | Reception to follow |
MONDAY |
7:30 am - 8:30 am | Breakfast |
9:00 AM | Session 2: From Bench to the Bedside |
| Discussion Leader: Bernard Levin, M.D., MD Anderson Cancer Center |
9:15 | LeyRoy Hood, M.D., Ph.D., Institute of System Biology
System Approach to Cancer Biology |
10:00 - 10:20 | Coffee |
10:20 | Nita Maihle, Ph.D., Mayo Clinic
Emerging Serum Biomarkers: Potential Clinical Utility of EGF Receptor Isoforms |
11:00- 11:10 AM | GRC Participants Photo |
11:20 | Gordon Mills, M.D., Ph.D., MD Anderson Cancer Center
Lysophospholipids in the Pathophysiology, Diagnosis, and Management of Cancer |
12:10-12:30 | Poster Presentations: |
12:10 | Vy Do, PhD-, Northwestern University
Rho-Kinase in LPA-Mediated Ovarian Cancer Migration and Invasion |
12:20 | Carol J Fabian, M.D., University of Kansas Medical Center
Comparison of Epithelial Cell Morphology and Epithelial Cell Yields in High Risk Women Undergoing Random Periareolar FNA and Ductal Lavage |
12:30 pm | Lunch |
1:30 pm - 6:00 pm | Social Activities |
6:00 pm | Dinner |
7:30 PM | Session 3: Clinical and Epidemiologic Approaches |
| Discussion Leader: Margaret Spitz, M.D., M.P.H., MD Anderson Cancer Center |
| Principal Speaker(s): |
| Michael Pollack, M.D., Ph.D., McGill University
Detection of Host Factors that Influence the Time Course of Carcinogenesis and the Behavior of Early Cancers: The Case of Insulin-like Growth Factors |
8:10 PM | Nicole Urban, Ph.D., University of Washington-Seattle
The Potential Use of a Panel of Serum Markers for Ovarian Cancer Screening |
8:50 PM | Harvey Mohrenweiser, Ph.D., Lawrence Livermore National Laboratory Common Polymorphisms and Susceptibility: Examples from the Study of DNA Repair Genes |
9:30 PM | Poster Session #1 Reception |
TUESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 AM | Session 4: Molecular Profiling of Tumor Tissue and Cell Lines |
| Discussion Leader: Edison T. Liu, M.D., Genome Institute of Singapore |
| Principal Speaker(s) |
9:15AM | Lee Ellis, M.D., MD Anderson Cancer Center
Challenges in the Development of anti-angiogenic Therapy |
10:00-10:20 AM | Coffee |
10:20 | Pat Brown, M.D., Ph.D., Stanford University
Genomic Expression of Cancer Detection |
11:20 | John Weinstein, Ph.D., National Cancer Institute
Molecular Profiling for Cancer Drug Discovery |
12:10-12:30 | Poster Presenters:
Ali Houdi, Eastern Virginia Medical School
Human Line-1 element-induced cell killing as potential cancer therapy |
| Sunjoo Jeong, Dankook University, Korea
Specific Detection of the Cancer Cell Surface Sugar Antigen wit the Peptide and RNA aptamers |
12:30 pm | Lunch |
1:30 pm - 6:00 pm | Social Activities |
6:00 pm | Dinner |
7:30 PM | Session 5: Molecular Analysis |
| Discussion Leader: Sam Hanash, M.D., Ph.D., University of Michigan |
| Principal Speaker(s): |
7:45 | Richard Caprioli, M.D., Vanderbilt University
Profiling and Imaging of Proteins in Tissue by Mass Spectrometry: A Discovery Tool in Cancer Research |
8:30 | David Beer, Ph.D., University of Michigan
Molecular Analysis of Lung Cancer using Genomics and Proteomics |
9:00-9:30 | Adi Gazdar, M.D., UT Southwestern Medical Center
The presence of SV40 DNA sequences in human tumors |
9:30 -9:45 PM | Poster Session #2, |
| Poster Presenters: |
| Avtar Krishan, University of Miami Medical Center
High Resolution Flow Cytometric Analysis of Cancer Cells |
| Pascale F Macgregor, University Health Network, Toronto
Parallel Analysis of Sporadic Ovarian Carcinomas by SKY, CGH and cDNA Microarrays |
| Reception |
WEDNESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 AM | Session 6: Innovative Technologies for the Molecular Portrait of Cancer Cells |
| Discussion Leader: David Sidransky, M.D., Johns Hopkins University |
| Principal Speaker(s): |
| Emanuel Petricoin, Ph.D., Food and Drug Administration
FDA-NCI Clinical Proteomics Program: Technology Development and Application at the Bedside |
10:00-10:20 | Coffee |
10:20 | Olli Kallioniemi, M.D., Ph.D., National Cancer Institute
Application of Biochip Technologies for Cancer Diagnosis and Treatment |
11:15 | George Wright, Ph.D., Eastern Virginia Medical School
Biomarker Discovery and Diagnosis of Prostate Cancer Using SELDI Protein Biochip Mass Spectroscopy |
12:00- 12:30 | Poster Presenters: |
12:00 | Glenn D Prestwich, University of Utah
Lipid Signaling for Detection of Cancer |
12:15 | Karen K. Smith-McCune, University of California, San Francisco
Measurement of Human Papillomavirus Transcripts By Real Time Quantitative RT/PCR in Samples Collected for Cervical Cancer Screening |
12:30 pm | Lunch |
1:30 pm - 6:00 pm | Social Activities |
6:00 pm | Dinner |
7:30 PM | Session 7: Innovative use of Imaging Technologies |
| Discussion Leader: Robert Smith, M.D., American Cancer Society |
| Principal Speaker(s): |
7:30 PM | Hedvig Hricak, M.D., Ph.D., Memorial Sloan-Kettering
Innovations in Imaging: Prostate Cancer as an Example |
8:05 PM | Ed Hendrick, Ph.D., Northwestern University
Medical Imaging in 3D, 4D, and Beyond |
8:50 PM | G. Allan Johnson, Ph.D., Duke University
Image Based Phenotyping for the Basic Scientist |
9:30 PM | Poster Session #3 Reception |
THURSDAY |
7:30 am - 8:30 am | Breakfast |
9:00 AM | Session 8: Statistical and Computational Tools for Cancer Signatures Analysis |
| Discussion Leader: Ziding Feng, Ph.D., Fred Hutchinson Cancer Research Center |
9:15 AM | Principal Speaker(s): |
| Bradley Efron, Ph.D., Stanford University
Microarrays and Some Statistical Methods They Have Stimulated |
10:00-10:30 | Coffee |
10:30 | Terry Speed, Ph.D., University of California - Berkley
Preprocessing of cDNA Microarray Data |
11:05 | David Haynor, Ph.D., University of Washington
Working out the wiring diagram of transcriptional control |
11:45 | Steven Skates, Ph.D., Harvard University
Early Detection of Ovarian Cancer Using the Risk of Ovarian Cancer Algorithm Based on Longitudinal CA125 Measurements |
| Poster Presenter: |
12:10 | Djamel Medjahed, Ph.D., NCI-Frederic Cancer Research Center
Predictive Database on Protein-Expression maps |
12:25 | Trey Ideker, PhD, Institute for Systems Biology
poster title TBA |
12:30 pm | Lunch |
1:30 pm - 6:00 pm | Social Activities |
6:00 pm | Dinner |
7:30 PM | Session 9: Developing Technologies for Early Detection |
| Discussion Leader: Tom Hamilton, Ph.D., Fox-Chase Cancer Center |
| Principal Speaker(s): |
7:30 | Jeff Trent, M.D., National Cancer Institute
Genomic Expression Analysis for Cancer Detection |
8:15 | Barry Kacinski, M.D., Ph.D., Yale University
The Science Underlying the Early Detection of Ovarian Cancer |
8:45 | Peter Gascoyne, Ph.D., MD Anderson Cancer Center
Integrated Instruments for Point of Care Detection and Molecular Characterization of Cancer |
9:30 PM | Poster Session #4 Reception to follow |
FRIDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am | Departure |