SUNDAY |
2:00 pm - 9:00 pm | Arrival and Check-in |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | MAKING CONTACT: APOPTOTIC CELL RECOGNITION |
7:30 pm - 7:50 pm | Welcome & Logistics of the Conference (Co-chairs) |
| Discussion Leader: Valerie Fadok (National Jewish Medical and Research Center) |
7:50 pm - 8:30 pm | Kirsten Lauber (University of Tuebingen)
"Release of 'Find-me' signals by apoptotic cells: Role of Ca2+-independent phospholipase A2" |
8:30 pm - 9:30 pm | KEYNOTE ADDRESS: Peter Henson (National Jewish Medical and Research Center)
"Ligands on apoptotic cells and the receptors that recognize them" |
MONDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | MUTUAL ATTRACTION: APOPTOTIC CELL LIGANDS/MACROPHAGE RECEPTORS |
| Discussion Leader: Giovanna Chimini (Marseille) |
9:00 am - 9:35 am | Catherine Godson (University College Dublin)
"Lipoxins and annexin 1 regulate macrophage phagocytosis of apoptotic leukocytes" |
9:35 am - 10:00 am | Adam Lacy-Hulbert (Massachusetts Institute of Technology)
"Important roles for alpha (V) integrins in apoptotic cell phagocytosis and immune responses revealed by conditional gene targeting" |
10:00 am | Coffee Break |
10:30 am - 11:10 am | Andreas Lengeling (German Research Center for Biotechnology, Braunschweig)
"Revealing the secrets of phosphatidylserine receptor functions" |
11:10 am - 11:50 am | Valerian Kagan (University of Pittsburgh)
"Lipid oxidation and the recognition of apoptotic cells" |
11:50 am - 12:15 pm | Shyra Gardai (National Jewish Medical and Research Center)
"Cell surface calreticulin initiates clearance of viable or apoptotic cells" |
12:15 pm | Group Photo |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session (Last name A - K) |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | HOLDING ON: APOPTOTIC CELL/MACROPHAGE BRIDGING |
| Discussion Leader: Patrick Williamson (Amherst College) |
7:30 pm - 8:10 pm | Glenn Matsushima (University of North Carolina)
"Mer TK in autoimmunity and inflammation" |
8:10 pm - 9:10 pm | KEYNOTE ADDRESS: Shigekazu Nagata (Osaka University Medical School)
"Failure of degradation and engulfment of apoptotic cells" |
TUESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | FEELINGS INSIDE: MACROPHAGE SIGNALING PATHWAYS |
| Discussion Leader: Michael Hengartner (University of Zurich) |
9:00 am - 9:30 am | Keith Elkon (University of Washington)
"Apoptotic Cells Tolerize CD4 and CD8 T cells by multiple pathways" |
9:30 am - 10:00 am | David Ucker (University of Illinois College of Medicine)
"Specific immune recognition of apoptotic cells: a ubiquitous receptor-coupled cellular process not restricted to professional phagocytes and independent of PSR" |
10:00 am | Coffee Break |
10:30 am - 11:10 am | Raymond Birge (New Jersey Medical School)
"Integration of PS signals and the phagocytosis of apoptotic cells" |
11:10 am - 11:50 am | Kodi Ravichandran (University of Virginia)
"Signaling during engulfment: The beginnings of a good meal" |
11:50 am - 12:30 pm | Simon Brown (University of Edinburgh)
"CD31 promotes leukocyte engulfment: an update on mechanisms" |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session (Last name L - Z) |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | OTHER PARTNERS: PHAGOCYTE DIVERSITY |
| Discussion Leader: Valerian Kagan (University of Pittsburgh) |
7:30 pm - 8:10 pm | Jeffrey Curtis (University of Michigan)
"Alveolar macrophages, lonely sentinels of the lungs" |
8:10 pm - 8:50 pm | Silvia Finnemann (Cornell University)
"Control of retinal clearance phagocytosis by integrin signaling" |
8:50 pm - 9:30 pm | Alon Krispin (Hadassah-Hebrew University)
"Monocyte apoptosis induces expression and secretion of a 26 kDa protein that mediates engulfment of apoptotic monocytes and immune suppression of immature dendritic cells" |
WEDNESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | LESSONS FROM LITTLE ONES: CLEARANCE IN INVERTEBRATES |
| Discussion Leader: Yoshinobu Nakanishi (Kanazawa University) |
9:00 am - 9:30 am | Esty Kurant (Rockefeller University)
"The novel Drosophila gene, six microns under (simu), functions in the phagocytosis of apoptotic particles" |
9:30 am - 10:00 am | Bo Zhai (Massachusetts General Hospital)
"Screening for new genes involved in the phagocytosis of apoptotic cells in Drosophila" |
10:00 am | Coffee Break |
10:30 am - 11:10 am | Michael Hengartner (University of Zurich)
"Genetic analysis of recognition mechanisms in C. elegans" |
11:10 am - 11:50 am | Akiko Shiratsuchi (Kanazawa University)
"Phagocytosis of apoptotic cells in Drosophila: Draper-mediated and phosphatidylserine-independent phagocytosis of apoptotic cells by Drosophila hemocytes/macrophages" |
11:50 am - 12:30 pm | Loriano Ballarin (University of Padua)
"Ancient mechanisms of apoptotic cell removal in Ascidians" |
12:30 pm | Lunch |
1:30 pm - 6:00 pm | Free Time |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | ADAPTING: CO-OPTING APOPTOTIC MECHANISMS |
| Discussion Leader: Robert Schlegel (Penn State University) |
7:30 pm - 8:10 pm | Giovanna Chimini (Marseille)
"ABCA1 and macrophage physiology: more than engulfment" |
8:10 pm - 8:50 pm | Marcello Barcinski (Instituto Nacional de Cancer, Rio de Janeiro)
"Role of PS exposure on host-parasite interaction" |
8:50 pm - 9:30 pm | Ger van Zandbergen (Luebeck University)
"Unicellular parasites misuse of the apoptotic eat me signal phosphatidylserine for establishment of a productive infection in a multicellular host" |
THURSDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | ENDING IT: ALTERNATIVE MECHANISMS OF KILLING |
| Discussion Leader: Kodi Ravichandran (University of Virginia) |
9:00 am - 9:40 am | SY Seong (Seoul National University)
"Hydrophobicity: an ancient damage-associated molecular pattern" |
9:40 am - 10:00 am | Business Meeting |
10:00 am | Coffee Break |
10:30 am - 11:10 am | Eric Baehrecke (University of Maryland)
"The role of autophagy in degradation of dying cells" |
11:10 am - 11:40 am | Dmitri Krysko (Ghent University)
"Macrophages use different internalization mechanisms for the clearance of apoptotic and necrotic cells" |
11:40 am - 12:05 pm | Masatoshi Beppu (Tokyo University)
"Induction of CD43 capping on nonapoptotic cells leads to carbohydrate-mediated macrophage recognition" |
12:05 pm - 12:30 pm | J. Magarian Blander (Yale University School of Medicine)
"Simultaneous phagocytosis of microbial and apoptotic cells: whose antigens win presentation by MHC Class II molecules?" |
12:30 pm | Lunch |
1:30 pm - 6:00 pm | Free Time |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | EXPLOITATION: THERAPEUTIC APPLICATIONS |
| Discussion Leader: David Peritt (Therakos) |
7:30 pm - 8:10 pm | Patrizia Rovere-Querini (Vita-Salute San Raffaele University)
"Clearance of apoptotic cells, endogenous adjuvants and immune responses" |
8:10 pm - 8:45 pm | Udo Gaipl (University of Erlanger-Nuremberg)
"Clearance defects in some patients with systemic lupus erythematosus" |
8:45 pm - 9:10 pm | Philippe Saas (Inserm Besancon)
"Intravenous apoptotic leukocyte infusion and hematopoietic cell engraftment" |
9:10 pm - 9:30 pm | James George (University of Alabama - Birmingham)
"Therapeutic infusion of apoptotic cells: Real-world clinical effects in heart transplant recipients and possible mechanisms" |
FRIDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am | Depart |