SUNDAY |
2:00 pm - 11:00 pm | Arrival and Check-in |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | POST-TRANSLATIONAL REGULATION OF PROTEIN FUNCTION |
| Discussion Leader: Brenda Schulman (St. Jude’s Children’s Research Hospital) |
7:30 pm - 7:45 pm | Welcome and Introductory Remarks |
7:45 pm - 8:10 pm | Brenda Schulman (St. Jude’s Children’s Research Hospital) "E1 and E2 Structure and Function" |
8:10 pm - 8:20 pm | Discussion |
8:20 pm - 8:45 pm | Wade Harper (Harvard Medical School) "Cell Cycle and Checkpoint Control by the Ubiquitin Pathway" |
8:45 pm - 8:55 pm | Discussion |
8:55 pm - 9:20 pm | Chris Lima (Sloan Kettering) "Conjugation and Recognition of the Small Ubiquitin-like Modifier SUMO" |
9:20 pm - 9:30 pm | Discussion |
MONDAY |
7:30 am - 8:30 am | Breakfast |
8:30 am | Group Photo |
9:00 am - 12:30 pm | REGULATION OF CELL GROWTH |
| Discussion Leader: Ted Powers (UC - Davis) |
9:00 am - 9:25 am | Bruce Edgar (Fred Hutchinson Cancer Research Center) "Cell cycle exit at differentiation" |
9:25 am - 9:35 am | Discussion |
9:35 am - 10:00 am | David Sabatini (MIT, Whitehead Institute for Biomedical Research) "Regulation of growth by the mTOR pathway" |
10:00 am - 10:10 am | Discussion |
10:10 am - 10:40 am | Coffee Break |
10:40 am - 11:05 am | Ted Powers (UC - Davis) "TOR Signaling in Budding Yeast" |
11:05 am - 11:15 am | Discussion |
11:15 am - 11:40 am | Jon Warner (Albert Einstein College of Medicine) "Ribosome Biosynthesis: a System in Balance" |
11:40 am - 11:50 am | Discussion |
11:50 am - 12:15 pm | Erin O’Shea (Harvard University) "Cellular Nutrient Homeostasis" |
12:15 pm - 12:25 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | NOVEL TOOLS TO STUDY CELLULAR FUNCTION |
| Discussion Leader: Natalie Ahn (University of Colorado) |
7:30 pm - 7:55 pm | Alice Ting (MIT) "Site-specific Protein Labeling with Biotin Ligase and Single Molecule Imaging of Protein Trafficking" |
7:55 pm - 8:00 pm | Discussion |
8:00 pm - 8:25 pm | Natalie Ahn (University of Colorado) "Shotgun Proteomics -- Hitting the Target" |
8:25 pm - 8:30 pm | Discussion |
8:30 pm - 8:55 pm | Mats Gustafsson (UCSF) "Ultra-high-Resolution Fluorescence Microscopy by Nonlinear Structured Illumination" |
8:55 pm - 9:00 pm | Discussion |
9:00 pm - 9:25 pm | Tom Kirchhausen (Harvard Medical School) "Cell based screening of small molecules" |
9:25 pm - 9:30 pm | Discussion |
TUESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | CELL BIOLOGY OF DISEASE |
| Discussion Leader: Larry Goldstein (UCSD) |
9:00 am - 9:25 am | Wes Sundquist (University of Utah) "The Molecular Biology of HIV Budding" |
9:25 am - 9:35 am | Discussion |
9:35 am - 10:00 am | Larry Goldstein (UCSD) "Axonal transport and Alzheimer’s" |
10:00 am - 10:10 am | Discussion |
10:10 am - 10:30 am | Coffee Break |
10:30 am - 10:55 am | David Chan (Caltech) "Mitochondrial Dynamics in Development and Disease" |
10:55 am - 11:05 am | Discussion |
11:05 am - 11:30 am | Mina Bissell (LBNL) "Models to Study Morphogenesis and Tissue-specificity: Challenges for the 21st century" |
11:30 am - 11:40 am | Discussion |
11:40 am - 12:05 pm | Elena Rugarli (Telethon Institute of Genetics) "Dissecting Hereditary Spastic Paraplegia to Rescue Degenerating Axons" |
12:05 pm - 12:15 pm | Discussion |
12:15 pm - 12:25 pm | Dianne Schwarz (Harvard University) "Selective silencing of a mutant SOD1 allele by RNA interference" |
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | EVOLUTION |
| Discussion Leader: Andrew Murray (Harvard University) |
7:30 pm - 7:55 pm | Harmit Malik (Fred Hutchinson Cancer Research Center) "Evolution of Intrinsic Immunity against retroviruses in primate genomes" |
7:55 pm - 8:00 pm | Discussion |
8:00 pm - 8:25 pm | Jeff Boeke (Johns Hopkins University) "Impact of High Transposon Copy Numbers on the Genome" |
8:25 pm - 8:30 pm | Discussion |
8:30 pm - 8:55 pm | Andrew Murray (Harvard University) "Defining an Evolutionary Speed Limit" |
8:55 pm - 9:00 pm | Discussion |
9:00 pm - 9:25 pm | Roy Kishony (Bauer Center for Genomics Research, Harvard University) "Functional Classification in Gene and Drug Interaction Networks" |
9:25 pm - 9:30 pm | Discussion |
WEDNESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | MEMBRANE DYNAMICS: REGULATION OF MEMBRANE STRUCTURE AND COMPOSITION |
| Discussion Leader: Randy Schekman (UC - Berkeley) |
9:00 am - 9:25 am | Randy Schekman (UC - Berkeley) "Exomer: A Novel Coat Protein Complex Required for Selective Protein Traffic from the Trans Golgi Compartment" |
9:25 am - 9:35 am | Discussion |
9:35 am - 10:00 am | Harvey McMahon (MRC) "Membrane Bending: from Biophysics to Trafficking Pathways" |
10:00 am - 10:10 am | Discussion |
10:10 am - 10:40 am | Coffee Break |
10:40 am - 11:05 am | Ben Glick (University of Chicago) "Self-Organization of Early Secretory Compartments" |
11:05 am - 11:15 am | Discussion |
11:15 am - 11:40 am | Jennifer Lippincott-Schwartz (NIH) "Trafficking dynamics" |
11:40 am - 11:50 am | Discussion |
11:50 am - 12:00 pm | Eric Weiss (Northwestern University) "Control of the Yeast RAM Network Kinase Cbk1" |
12:00 pm - 12:10 am | Discussion |
12:10 pm - 12:20 pm | Scott Chen (MIT) "New Methodology for Detecting Protein-Protein Interactions in Living Cells Using Biotin Ligase" |
12:20 pm - 12:25 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:00 pm - 7:30 pm | Business Meeting |
| (Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair) |
7:30 pm - 9:30 pm | EPIGENETIC REGULATION |
| Discussion Leader: Barbara Meyer (UC - Berkeley) |
7:30 pm - 7:55 pm | Jeannie Lee (Harvard Medical School) "Evidence for Transgenerational X-chromosome Silencin" |
7:55 pm - 8:00 pm | Discussion |
8:00 pm - 8:25 pm | Barbara Meyer (UC - Berkeley) "Targeting the C. elegans dosage compensation complex to X chromosomes" |
8:25 pm - 8:30 pm | Discussion |
8:30 pm - 8:55 pm | Brendan Cormack (Johns Hopkins University) "Transcriptional Silencing and Adherence in Candida Glabrata" |
8:55 pm - 9:00 pm | Discussion |
9:00 pm - 9:25 pm | Steve Henikoff (Fred Hutchinson Cancer Research Center) "Histone Dynamics in Transcription and Epigenetic Regulation" |
9:25 pm - 9:30 pm | Discussion |
THURSDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | REGULATION OF SIZE AND STRUCTURE OF CELLULAR STRUCTURES AND ORGANELLES |
| Discussion Leader: Jodi Nunnari (UC - Davis) |
9:00 am - 9:25 am | Jodi Nunnari (UC - Davis) "Mitochondria" |
9:25 am - 9:35 am | Discussion |
9:35 am - 10:00 am | Bill Wickner (Dartmouth) "Vacuole fusion by a Rab, its effector, SNAREs, and special lipids, all dancing in a ring" |
10:00 am - 10:10 am | Discussion |
10:10 am - 10:40 am | Coffee Break |
10:40 am - 11:05 am | Arash Komeili (UC - Berkeley) "Cell Biology of the Bacterial Magnetosome" |
11:05 am - 11:15 am | Discussion |
11:15 am - 11:40 am | David Ron (NYU Medical Center) "Mechanisms that re-model the Stressed Endoplasmic Reticulum" |
11:40 am - 11:50 am | Discussion |
11:50 am - 12:15 am | Wallace Marshall (UCSF) "Dynamics and Feedback in the Flagellar Length Control System" |
12:15 am - 12:25 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | ROLES FOR RNAS IN CELLULAR REGULATION |
| Discussion Leader: Kathy Collins (Berkeley) |
7:30 pm - 7:55 pm | Victor Ambros (Dartmouth University) "MicroRNA-mRNA Regulatory Interactions in C. elegans" |
7:55 pm - 8:00 pm | Discussion |
8:00 pm - 8:25 pm | Danesh Moazed (Harvard Medical School) "RNAi mediated assembly of heterochromatin" |
8:25 pm - 8:30 pm | Discussion |
8:30 pm - 8:55 pm | Rachel Green (Johns Hopkins University) "Controlled Catalysis by tRNAs and Release Factors during Translation" |
8:55 pm - 9:00 pm | Discussion |
9:00 pm - 9:25 pm | Kathy Collins (Berkeley) "Telomerase" |
9:25 pm - 9:30 pm | Discussion |
FRIDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am | Departure |