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Atherosclerosis
Gordon Research Conference

Systems-Interaction in Atherosclerosis

Dates

June 18-23, 2017

Location

Grand Summit Hotel at Sunday River
Newry, ME Site Information

Organizers

Chairs:
Matthias Nahrendorf & Stefanie Dimmeler

Vice Chairs:
Lynn Hedrick & Carlos Fernandez-Hernando

Application Deadline

Applications for this meeting must be submitted by May 21, 2017. Please apply early, as some meetings become oversubscribed (full) before this deadline. If the meeting is oversubscribed, it will be stated here. Note: Applications for oversubscribed meetings will only be considered by the Conference Chair if more seats become available due to cancellations.

Meeting Description

Several decades of successful reductionist research led to substantial inroads in understanding the pathophysiology of atherosclerosis. This work established for instance time-tested and new treatment options such as statins and PCSK9 inhibitors. At the 2017 Gordon Atherosclerosis conference, we propose to discuss how connection of traditionally isolated research fields related to atherosclerosis may instill capabilities to design conceptually new treatment strategies. Recent advances, for instance uncovering interactions of metabolism and microbiota with systemic inflammation, highlight that building the "atherosclerosis connectome" has already begun. We propose to discuss, among others, the following questions: How do microRNA, other novel non-coding RNAs and altered gene expression patterns influence cellular action, metabolism and immunity? Can we retrain immunity towards inflammation resolution? How are the hematopoietic and central nervous system affected in atherosclerosis? Where do stromal and immune cells originate, and how do they interact in disease progression? Can imaging provide dynamic "biopsies" in out-of-reach tissues? How do myocardial and vascular health interact? We will strive to make this conference a catalyst for entering new research fields, providing the traditionally communicative environment that has fostered atherosclerosis research since the first Gordon Atherosclerosis conference happened in 1973. No matter whether you were born before or after that date, please consider joining us in beautiful Sunday River!

Related Meeting

This GRC will be held in conjunction with the "Atherosclerosis" Gordon Research Seminar (GRS). Those interested in attending both meetings must submit an application for the GRS in addition to an application for the GRC. Refer to the associated GRS program page for more information.

Contributors

Preliminary Program

The topics and speakers for the conference sessions are displayed below (italics denote discussion leaders). The Conference Chair is currently developing their detailed program, which will include the complete meeting schedule, as well as the talk titles for all speakers. The detailed program will be available by February 18, 2017. Please check back for updates.

  • Adaptive Immunity – Friend or Foe?
    (Lesca Holdt / Elena Galkina / Klaus Ley / Andrew Lichtman / Ziad Mallat)
  • Hematopoiesis Modified by Cardiovascular Risk and Co-Morbidity
    (Nadia Rosenthal / Ajay Chawla / Partha Dutta / Paul Frenette / Filip Swirski / Alan Tall)
  • Innate Immunity and Plaque Cell Origins
    (Gwendalyn Randolph / Catherine Hedrick / Gary Owens / Clinton Robbins / Christian Weber)
  • Reading and Reaching Plaque Biology
    (Elena Galkina / Zahi Fayad / Thorsten Mempel / Willem Mulder / Gwendalyn Randolph)
  • Myocardial Ischemia, Healing and Regeneration
    (Catherine Hedrick / Slava Epelman / Kory Lavine / Nadia Rosenthal)
  • Coding and Non-Coding Genetics
    (Stefanie Dimmeler / Jake Lusis / Kathryn Moore / Lesca Holdt / William Sessa)
  • Innate Immune Memory and Epigenetics
    (Michelle Olive / Eike Latz / Mihai Netea / Konstantinos Stellos)
  • Microbiotic, Metabolic and Lipid Modifiers of Atherosclerosis
    (Katey Rayner / Christoph Binder / Stanley Hazen / Peter Tontonoz)
  • Clinical Input and Output
    (Kathryn Moore / Peter Libby / Heribert Schunkert / Andreas Zeiher)
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