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Bioenergetics
Gordon Research Conference

From Molecular Structures and Mechanisms to Cellular Bioenergetics in Health and Disease

Dates

June 4-9, 2017

Location

Proctor Academy
Andover, NH Site Information

Organizers

Chair:
Judy Hirst

Vice Chair:
Wayne D. Frasch

Application Deadline

Applications for this meeting must be submitted by May 7, 2017. Please apply early, as some meetings become oversubscribed (full) before this deadline. If the meeting is oversubscribed, it will be stated here. Note: Applications for oversubscribed meetings will only be considered by the Conference Chair if more seats become available due to cancellations.

Meeting Description

The 2017 Gordon Research Conference on Bioenergetics will bring together scientists interested in the molecular and cellular aspects of biological energy conversion. The structures and mechanisms that biology uses to control, handle and conserve energy are fundamental to life, and central to many aspects of human health and disease. The meeting will promote an integrated, multidisciplinary view of energy metabolism, by encouraging discussions and exchange of information between researchers from a broad range of bioenergetics-related scientific disciplines. It will focus broadly on the following three areas. First, on new developments in the structure, mechanism, organisation and regulation of the large and complicated proton-pumping enzyme complexes of biological energy conservation: the respiratory electron transporting complexes, and the rotary ATP synthase machines. Second, on the roles and functions of the bioenergetic complexes in the cell – not only the production of ATP, but a significant contribution to oxidative stress, and the essential support of many diverse cellular metabolic pathways. Third, how bioenergetics enzymes can be exploited as drug targets in human diseases, including in cancer, mitochondrial and neurodegenerative diseases, with an additional emphasis on targeting the bioenergetics enzymes particular to pathogens. Finally, clear priorities for the meeting are to provide a platform for researchers on every level to present their most recent findings (whether in a formal scientific session or as a poster presentation) and to engage in active, stimulating and unfettered discussions. Particular emphasis will be placed on engaging postdoctoral researchers and graduate students in the meeting, and on promoting an atmosphere that is both welcoming and inspiring for younger researchers, as well as for established ones.

Contributors

Preliminary Program

The topics and speakers for the conference sessions are displayed below (italics denote discussion leaders). The Conference Chair is currently developing their detailed program, which will include the complete meeting schedule, as well as the talk titles for all speakers. The detailed program will be available by February 4, 2017. Please check back for updates.

  • The Complexity of Mammalian Complex I
    (Judy Hirst / Jiapeng Zhu / Mike Ryan / Ulrich Brandt)
  • The Respiratory Chain and Oxidative Stress
    (Susanne Arnold / Artur Osyczka / Alberto Sanz Montero / Lothar Kussmaul / Isha Jain)
  • Bioenergetics on the Single Molecule Level
    (Robert Gennis / Lars Jeuken / Hiroyuki Noji / Karin Busch)
  • Attacking the Bioenergetic Enzymes in Pathogens
    (Anthony Moore / Dirk Bald / Gregory Cook / Kiyoshi Kita / Akhil Vaidya)
  • Structures and Functions of Supercomplex Assemblies
    (Carola Hunte / Peter Brzezinski / Karen Davies / Cristina Ugalde)
  • Determining the Structures and Mechanisms of Complex Proton-Pumping Redox Enzymes
    (Thorsten Friedrich / Ville Kaila / Peter Rich / Leonid Sazanov)
  • Late-Breaking Topics / Young Investigator Presentations
    (Wayne Frasch)
  • F- and V-Type ATPases: Molecular Machines and Drug Targets
    (Karlett Parra / Michael Forgac / Thomas Meier / John Walker)
  • The Electron Transport Chain as an Essential Component of Cellular Metabolic Networks
    (David Nicholls / Kivanc Birsoy / Christian Frezza / Jared Rutter)
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