Gordon Research Conferences
Meeting Details

Drug Metabolism
Gordon Research Conference

Uncovering Complexity in Drug Metabolism in the Cell and the Clinic


July 8-13, 2018


Holderness School
Holderness, NH Site Information


Swati Nagar

Vice Chair:
Griff Humphreys

Application Deadline

Applications for this meeting must be submitted by June 10, 2018. Please apply early, as some meetings become oversubscribed (full) before this deadline. If the meeting is oversubscribed, it will be stated here. Note: Applications for oversubscribed meetings will only be considered by the Conference Chair if more seats become available due to cancellations.

Meeting Description

The 48th Drug Metabolism Gordon Research Conference will focus on cutting edge research in drug ADME (absorption, distribution, metabolism, elimination), encompassing a wide range of research from the cellular level to the patient. Complexity in biological systems and enzymatic processes is continually uncovered in science. The conference aims to illuminate this biological complexity, often studied with simple biological and mathematical models, in order to enhance the application of new knowledge to understanding drug safety and efficacy in the clinic. The 2018 conference will include a keynote presentation on understanding drug toxicity, and scientific sessions on structure/function of drug metabolizing enzymes, interactions between the cell membrane and enzyme/transporter proteins, drug-drug interactions and toxicity, modeling drug metabolism and transport, drug disposition and toxicity in special (pediatric, understudied, and disease) populations, and case studies based on regulatory guidances. All presentations will include unpublished data, with sessions designed for maximal audience discussion. Attendees are encouraged to submit posters for presentation at the poster session organized by the Vice Chair Dr. Griff Humphreys. The Wednesday evening session will feature oral presentations by young investigators (graduate students and postdoctoral trainees) selected from the submitted poster abstracts. The conference is collegial and informal in nature, with ample opportunity to discuss unpublished research, make collaborative connections, and develop new ideas. Young investigators have easy access to individual mentoring from established investigators, as well as during career advice sessions planned during the week.

The registration fee includes all meals and housing on the Holderness School campus. In addition to the scientific sessions, attendees are strongly encouraged to enjoy the many outdoor recreational activities in the New Hampshire area. Afternoon traditions of this conference include an Academia vs. Industry softball game (no experience necessary, bring your gloves!), and hiking and kayaking/canoeing outings in the White Mountains.


Gordon Research Conferences
Sekisui XenoTech

Session Titles

The Conference will consist of nine sessions, on the topics listed below. The Conference Chair is currently developing their preliminary program, which will include the names of the invited speakers and discussion leaders for each of these sessions. The preliminary program will be available by November 15, 2017. Please check back for updates.

  • Keynote Session: The Leading Edge in Uncovering Complex Drug Disposition and Toxicity
  • New Knowledge on Structure and Function of Drug Metabolizing Enzymes
  • The Cell Membrane in Relation to Enzymes and Transporters
  • Drug-Drug Interactions and Toxicity
  • Models for Complex Metabolism and Transport
  • Special Populations: Pediatric Drug Metabolism and Pharmacokinetics
  • Young Investigator Presentations
  • Special Populations: Intricacies in Drug Disposition
  • The Complexity of Regulation: FDA Guidelines and Case Studies
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