SUNDAY |
4:00 pm - 8:00 pm | Arrival and Check-in (Office Closed 6:00 pm - 7:45 pm) |
6:00 pm | Dinner |
7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff |
7:40 pm - 9:30 pm | Clocks and Metabolism |
| Discussion Leader: Joseph Takahashi (University of Texas Southwestern Medical Center, Dallas, TX) |
7:40 pm - 7:50 pm | Opening Remarks |
7:50 pm - 8:10 pm | Joseph Bass (Northwestern University, Chicago, IL)
"Genetic Basis for Circadian Control of Nutrient Sensing"
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8:10 pm - 8:20 pm | Discussion |
8:20 pm - 8:40 pm | Carla Green (University of Texas Southwestern Medical Center, Dallas, TX)
"Regulation of Rhythmic Metabolism by Nocturnin"
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8:40 pm - 8:50 pm | Discussion |
8:50 pm - 9:10 pm | Mukesh Jain (Case Western Reserve University School of Medicine, OH)
"Circadian Regulation of Mammalian Nitrogen Homeostasis"
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9:10 pm - 9:20 pm | Discussion |
9:20 pm - 9:30 pm | General Discussion |
MONDAY |
7:30 am - 8:30 am | Breakfast |
8:30 am | Group Photo |
9:00 am - 12:30 pm | Linking Clocks, Sleep, Metabolic and Cardiovascular Processes |
| Discussion Leader: Eve van Cauter (University of Chicago, Chicago, IL) |
9:00 am - 9:10 am | Opening Remarks |
9:10 am - 9:30 am | Tarja Porkka-Heiskanen (University of Finland, Helsinki, Finland)
"Genes for Sleep and Metabolism"
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9:30 am - 9:40 am | Discussion |
9:40 am - 10:00 am | Radhika Basheer (Harvard Medical School, Boston, MA)
"Sleep and Brain Energy Metabolism: A Bidirectional Relationship"
|
10:00 am - 10:10 am | Discussion |
10:10 am - 10:35 am | Coffee Break |
10:35 am - 10:55 am | Martin E. Young (University of Alabama at Birmingham, Birmingham, AL)
"The Cardiomyocyte Circadian Clock Influences Cardiac Function and Dysfunction"
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10:55 am - 11:05 am | Discussion |
11:05 am - 11:25 am | Steven A. Shea (Harvard Medical School, Boston, MA)
"Endogenous Circadian Control of Cardiovascular Function in Humans"
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11:25 am - 11:35 am | Discussion |
11:35 am - 11:45 am | Hot Topics Speaker: Christian Kell (Goethe University, Frankfurt, Germany)
"How Time of Day affects Brain Function: Diurnal Network Dynamics underlying Stability of Visual Perception and Interindividual Variability in Motor Activity"
|
11:45 am - 11:50 am | Discussion |
11:50 am - 12:00 pm | Hot Topics Speaker: Frank A.J.L. Scheer (Harvard Medical School, Boston, MA)
"Repeated Melatonin Supplementation Improves Sleep in Hypertensive Patients Treated with β-Blockers"
|
12:00 pm - 12:05 pm | Discussion |
12:05 pm - 12:30 pm | General Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Sleep, Clocks and Feeding |
| Discussion Leader: Jim Horne (Loughborough University, Loughborough, UK) |
7:30 pm - 7:40 pm | Opening Remarks |
7:40 pm - 8:00 pm | Denis Burdakov (University of Cambridge, Cambridge, UK)
"Bidirectional Control of Sleep-Wake Circuits by Dietary Macronutrients"
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8:00 pm - 8:10 pm | Discussion |
8:10 pm - 8:30 pm | Ralph Mistlberger (Simon Fraser University, Burnaby, Canada)
"Food-entrained Rhythmicity: Interactions with Light and Melatonin"
|
8:30 pm - 8:40 pm | Discussion |
8:40 pm - 9:00 pm | Ken Wright (University of Colorado at Boulder, Boulder, CO)
"Mechanisms Linking Sleep Loss, Weight Gain and Obesity"
|
9:00 pm - 9:10 pm | Discussion |
9:10 pm - 9:30 pm | General Discussion |
TUESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Metabolic Clocks |
| Discussion Leader: Joseph Bass (Northwestern University, Chicago, IL) |
9:00 am - 9:10 am | Opening Remarks |
9:10 am - 9:30 am | Akhilesh Reddy (University of Cambridge, Cambridge, UK)
"Peroxiredoxins and the Circadian Clockwork"
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9:30 am - 9:40 am | Discussion |
9:40 am - 10:00 am | John Hogenesch (University Pennsylvania School of Medicine, Philadelphia, PA)
"Networks of the Mammalian Circadian Clock"
|
10:00 am - 10:10 am | Discussion |
10:10 am - 10:35 am | Coffee Break |
10:35 am - 10:55 am | Alan Gerber (University of Geneva, Geneva, Switzerland)
"Identification of Diurnal Signaling Pathways by Synthetic Tandem Repeat Promoter (STAR-PROM) Screening"
|
10:55 am - 11:05 am | Discussion |
11:05 am - 11:25 am | Joseph Takahashi (University of Texas Southwestern Medical Center, Dallas, TX)
"Interaction of the Clock and Usf1 Transcriptional Pathways: Another Metabolic Interface" |
11:25 am - 11:35 am | Discussion |
11:35 am - 11:45 am | Hot Topics Speaker: Rachel Leproult (Université Libre de Bruxelles, Brussels, Belgium)
"Impact of Sleep Loss and Circadian Misalignment on Insulin Sensitivity"
|
11:45 am - 11:50 am | Discussion |
11:50 am - 12:00 pm | Hot Topics Speaker: Alexander Ross (Rowett Institute of Nutrition, Aberdeen, UK)
"Photoperiod regulates Vitamin A and Wnt/beta-catenin Signalling in F344 Rats"
|
12:00 pm - 12:05 pm | Discussion |
12:05 pm - 12:30 pm | General Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Melatonin, Food, Peripheral Clocks and Metabolism |
| Discussion Leader: Michael Menaker (University of Virginia, Charlottesville, VA) |
7:30 pm - 7:40 pm | Opening Remarks |
7:40 pm - 8:00 pm | Andries Kalsbeek (University of Amsterdam, Amsterdam, The Netherlands)
"Metabolic Rhythms and the Interplay of Hypothalamic, Autonomic and Peripheral Clocks"
|
8:00 pm - 8:10 pm | Discussion |
8:10 pm - 8:30 pm | Carolina Escobar (Universidad Nacional Autónoma de México, México)
"The Entraining Power of Food: Is It the Third Arm of the Clock?"
|
8:30 pm - 8:40 pm | Discussion |
8:40 pm - 9:00 pm | Jeffrey Gimble (Louisiana State University System, Louisiana, LA)
"Circadian Clocks in Adipose Tissue"
|
9:00 pm - 9:10 pm | Discussion |
9:10 pm - 9:30 pm | General Discussion |
WEDNESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Interactions between Light, Sleep, Clocks and Metabolism |
| Discussion Leader: Ignacio Provencio (University of Virginia, Charlottesville, VA) |
9:00 am - 9:10 am | Opening Remarks |
9:10 am - 9:30 am | Etienne Challet (Université de Strasbourg, Strasbourg, France)
"Interactions between Light, Metabolism and Brain Clocks"
|
9:30 am - 9:40 am | Discussion |
9:40 am - 10:00 am | Steven Lockley (Harvard Medical School, Boston, MA)
"Non-linear Dynamics of Photic Circadian Resetting in Humans"
|
10:00 am - 10:10 am | Discussion |
10:10 am - 10:35 am | Coffee Break |
10:35 am - 10:55 am | Marijke Gordijn (University of Groningen, Groningen, The Netherlands)
"Light Exposure and the Rhythm of Melatonin in Humans under Natural Circumstances"
|
10:55 am - 11:05 am | Discussion |
11:05 am - 11:25 am | Phyllis Zee (Northwestern University, Chicago, IL)
"Role of Chronotype and Sleep Timing on Caloric Intake and BMI"
|
11:25 am - 11:35 am | Discussion |
11:35 am - 11:45 am | Hot Topics Speaker: Claudia Coomans (Leiden University Medical Center, Leiden, The Netherlands)
"The Suprachiasmatic Nucleus controls Circadian Energy Metabolism and Insulin Sensitivity"
|
11:45 am - 11:50 am | Discussion |
11:50 am - 12:00 pm | Hot Topics Speaker: Kathryn Reid (Northwestern University, Chicago, IL)
"Associations between Meal Timing, Caloric Intake and Obesity"
|
12:00 pm - 12:05 pm | Discussion |
12:05 pm - 12:30 pm | General Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:00 pm - 7:30 pm | Business Meeting |
| Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair |
7:30 pm - 9:30 pm | Shift Work, Sleep Restriction, Metabolic and Cardiovascular Function |
| Discussion Leader: Josephine Arendt (University of Surrey, Guildford, UK) |
7:30 pm - 7:40 pm | Opening Remarks |
7:40 pm - 8:00 pm | Till Roenneberg (Ludwig-Maximilians-Universität, Munich, Germany)
"Shift-work Research Needs Good Models"
|
8:00 pm - 8:10 pm | Discussion |
8:10 pm - 8:30 pm | Naomi Rogers (Central Queensland University, Mackay, Australia)
"Impact of shiftwork on metabolic health" |
8:30 pm - 8:40 pm | Discussion |
8:40 pm - 9:00 pm | Sampsa Puttonen (Finnish Institute of Occupational Health, Helsinki, Finland)
"Short- and Long-term Effects of Shift Work on Cardiovascular Function"
|
9:00 pm - 9:10 pm | Discussion |
9:10 pm - 9:30 pm | General Discussion |
THURSDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Melatonin, Sleep and Metabolism |
| Discussion Leader: Jörg H. Stehle (University of Frankfurt, Frankfurt, Germany) |
9:00 am - 9:10 am | Opening Remarks |
9:10 am - 9:30 am | Philippe Mourrain (Stanford University, Stanford, CA)
"Sleep and Hypocretin-Melatonin Interaction"
|
9:30 am - 9:40 am | Discussion |
9:40 am - 10:00 am | José Cipolla-Neto (University of Säo Paulo, Säo Paulo, Brazil)
"Melatonin and the Circadian Control of Energy Metabolism"
|
10:00 am - 10:10 am | Discussion |
10:10 am - 10:35 am | Coffee Break |
10:35 am - 10:55 am | Gabriella Gobbi (McGill University, Montreal, Canada)
"Sleep in Melatonin MT1 and MT2 Receptor Knockout Mice"
|
10:55 am - 11:05 am | Discussion |
11:05 am - 11:25 am | Oliver Rawashdeh (University of Frankfurt, Frankfurt, Germany)
"Melatonin and Daytime-Dependent Memory Processing in Mouse Hippocampus"
|
11:25 am - 11:35 am | Discussion |
11:35 am - 11:45 am | Hot Topics Speaker: Regina Markus (University of Säo Paulo, Säo Paulo, Brazil)
"Immune-Pineal Axis - How Infection impairs the Transduction of Darkness to Whole Body by Blocking Nocturnal Melatonin Rise"
|
11:45 am - 11:50 am | Discussion |
11:50 am - 12:00 pm | Hot Topics Speaker: Kyriaki Papantoniou (Centre for Research in Environmental Epidemiology, Barcelona, Spain)
"Melatonin and Sex Hormone Biomarkers and Light Intensity Measurements in Female and Male Permanent Night Shift Workers"
|
12:00 pm - 12:05 pm | Discussion |
12:05 pm - 12:30 pm | General Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 8:40 pm | Seasonality, Melatonin and Metabolism |
| Discussion Leader: Peter Morgan (University of Aberdeen, Aberdeen, UK) |
7:30 pm - 7:40 pm | Opening Remarks |
7:40 pm - 8:00 pm | Gisela Helfer (University of Aberdeen, Aberdeen, UK)
"Making Light Work of Body Weight Regulation: Photoperiod, Retinoic Acid Signalling and Inflammation"
|
8:00 pm - 8:10 pm | Discussion |
8:10 pm - 8:30 pm | Craig Heller (Stanford University, Stanford, CA)
"The Role of Circadian Rhythms in Controlling Seasonal Hypometabolism in Big and Small Hibernators"
|
8:30 pm - 8:40 pm | Discussion |
8:40 pm - 9:30 pm | Keynote |
| Discussion Leader: Vincent Cassone (University of Kentucky, Lexington, KY) |
8:30 pm - 8:40 pm | Opening Remarks |
8:40 pm - 9:20 pm | David Klein (National Institutes of Health, Bethesda, MD)
"Pineal Cell Biology: Past, Present and Future"
|
9:20 pm - 9:30 pm | Discussion |
FRIDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am | Departure |