Gordon Research Conferences
Meeting Details

Protein Folding Dynamics
Gordon Research Conference

Order, Disorder, and Aggregation in Protein Folding Dynamics


January 7-12, 2018


Hotel Galvez
Galveston, TX Site Information


Benjamin Schuler

Vice Chair:
Margaret S. Cheung

Application Deadline

Applications for this meeting must be submitted by December 10, 2017. Please apply early, as some meetings become oversubscribed (full) before this deadline. If the meeting is oversubscribed, it will be stated here. Note: Applications for oversubscribed meetings will only be considered by the Conference Chair if more seats become available due to cancellations.

Meeting Description

The concepts and methods of protein folding have diversified from the original "protein folding problem" into many rapidly advancing areas in physics, chemistry, and biology. A main purpose of this conference is to bring together researchers from these areas and in particular to foster the contact between experiment, theory, and simulation, since many of the key challenges in the field of protein folding dynamics can only be resolved in close collaboration between these disciplines.

Conceptually, the areas covered will range from elementary mechanisms, such as fast events in folding and the behavior of unfolded and intrinsically disordered proteins, to processes involving large molecular machinery, such as folding on the ribosome. The program will also address many of the resulting complex phenomena, including protein aggregation, intracellular phase transitions, and regulatory and evolutionary processes. Addressing these questions requires a versatile toolbox of techniques, and the methodological advances will be another important topic of the conference, both from the experimental and the theoretical side: from single-molecule techniques, spectroscopic methods with high time resolution, and experiments in live cells on the experimental side, to the latest developments in large-scale computing, models at different levels of coarse-graining, and analytical theory for describing biomolecular structure and dynamics. These developments have a large impact far beyond the protein folding field itself and fertilize many other areas of research. The conference will encourage interactions between junior scientists and established leaders in the field, e.g. through abstract-selected presentations and posters, and by means of the Gordon Research Seminar preceding the conference.

Related Meeting

This GRC will be held in conjunction with the "Protein Folding Dynamics" Gordon Research Seminar (GRS). Those interested in attending both meetings must submit an application for the GRS in addition to an application for the GRC. Refer to the associated GRS program page for more information.


Gordon Research Conferences
National Science Foundation

Preliminary Program

The topics and speakers for the conference sessions are displayed below (italics denote discussion leaders). The Conference Chair is currently developing their detailed program, which will include the complete meeting schedule, as well as the talk titles for all speakers. The detailed program will be available by September 7, 2017. Please check back for updates.

  • Keynote Session: Bridging Theory and Experiment
    (Jane Clarke / Peter Wolynes / William Eaton)
  • Protein Dynamics: Unfolded to Folded
    (Victor Munoz / Stefano Piana / Roland Netz / Gregory Bowman)
  • Disordered Proteins: Form and Function
    (Robert Best / Martin Blackledge / Teresa Head-Gordon)
  • Folding In Vivo and on the Ribosome
    (Susan Marqusee / John Christodoulou / Edward O'Brien)
  • Folding Transitions and Folding Paths
    (Michael Woodside / Dave Thirumalai / Dmitrii Makarov / Pietro Faccioli)
  • Misfolding and Aggregation
    (George Makhatadze / Joan-Emma Shea / Pernilla Wittung-Stafshede)
  • Intracellular Phase Separation: A New Paradigm of Protein Assembly
    (Rohit Pappu / Michael Rosen / Tanja Mittag / Ned Wingreen)
  • Single-Molecule Folding
    (Gilad Haran / Matthias Rief / Olga Dudko / Hoi Sung Chung)
  • Regulation and Evolution
    (Jose Onuchic / Vincent Hilser / Rama Ranganathan / Eugene Shakhnovich)
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