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Chemical & Biological Terrorism Defense
Gordon Research Conference

Innovation and Advancement: Fundamental Science Resulting in Next-Gen Solutions for Chemical and Biological Threats

Dates

March 5-10, 2017

Location

Ventura Beach Marriott
Ventura, CA Site Information

Organizers

Chair:
Steven R. Blanke

Vice Chairs:
Catharine M. Bosio & Patrick M. McNutt

Application Deadline

Applications for this meeting must be submitted by February 5, 2017. Please apply early, as some meetings become oversubscribed (full) before this deadline. If the meeting is oversubscribed, it will be stated here. Note: Applications for oversubscribed meetings will only be considered by the Conference Chair if more seats become available due to cancellations.

Meeting Description

The 2017 Gordon Research Conference (GRC) "Chemical and Biological Terrorism Defense" and its companion Gordon Research Seminar (GRS), will showcase exciting, innovative basic and translational research in the areas of biological and chemical threat agents, underscored by myriad opportunities for intensive discussion and networking between young and seasoned researchers from academia, government, medicine and biotech. This biennial international conference continues to be regarded by the biological and chemical defense communities as a premier venue for intellectual exchange and cross-disciplinary fertilization. To be held March 4-10 at the Ventura Marriott in Ventura California, the 2017 conference is led by Chair Steven Blanke, Ph.D., and Vice Chairs Catharine Bosio, Ph.D. and Patrick McNutt, Ph.D. Each scientific session will be crafted to highlight and engender themes and solutions common to both the chemical and biological threat communities. These, nine sessions will feature 32 invited speakers plus 4 young investigators/trainees that will be selected from the GRS, chosen to integrate cutting-edge research on: mechanisms, sources, and treatment of biological and chemical threats; the threat of non-human targets to human health disease; translational approaches for countermeasures and prevention; and cross-disciplinary solutions to detection and decontamination. Emerging issues of scientific and security importance, such as gene drives, and, new smart detection devices, will be featured. Poster sessions will promote extended discussions between investigators within and across disciplines and ranks. To integrate and develop the next generation of scientists in our field, the GRC will be preceded by a GRS. Together the Seminar and Conference promise to provide an exceptional forum for a diverse population of scientists to learn about cutting edge discoveries in the field, and consider and challenge the current paradigms, barriers and opportunities to advancing knowledge in the areas of defenses against chemical and biological threat agents.

Related Meeting

This GRC will be held in conjunction with the "Chemical & Biological Terrorism Defense" Gordon Research Seminar (GRS). Those interested in attending both meetings must submit an application for the GRS in addition to an application for the GRC. Refer to the associated GRS program page for more information.

Contributors

Meeting Program

Sunday
4:00 pm - 8:00 pmArrival and Check-in
6:00 pmDinner
7:30 pm - 7:40 pmWelcome / Introductory Comments by GRC Site Staff
7:40 pm - 9:30 pmKeynote Session: Chemical and Biological Threats: Emerging Challenges Requiring Innovative Solutions
Discussion Leader: Patrick McNutt (U.S. Army Medical Research Institute of Chemical Defense, USA)
7:40 pm - 7:50 pmOpening Remarks
7:50 pm - 8:00 pmIntroduction by Discussion Leader: Introduction and Perspective on Emerging Issues and Innovative Solutions Within the Chemical Threat Arena
8:00 pm - 8:30 pmArik Eisenkraft (Israeli Defense Forces, Israel)
"OP or Not OP, that Is the Question"
8:30 pm - 8:40 pmDiscussion
8:40 pm - 8:50 pmIntroduction by Discussion Leader: Introduction and Perspective on Emerging Issues and Innovative Solutions Within the Biological Threat Arena
8:50 pm - 9:20 pmOwain Edwards (CSIRO Land and Water, Australia)
"How Concerned Should We Be About Gene Drive Technologies?"
9:20 pm - 9:30 pmDiscussion
Monday
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmNeural Dysfunction Due to Biological and Chemical Threat Agents: Mechanisms, Detection, and Countermeasures
Discussion Leader: John McDonough (U.S. Army Medical Research Institute of Chemical Defense, USA)
9:00 am - 9:15 amIntroduction by Discussion Leader: Introduction and Perspectives on Emerging Issues and Innovative Solutions for Threat Agents Targeting Neural Function
9:15 am - 9:45 amDouglas Cerasoli (U.S. Army Medical Research Institute of Chemical Defense, USA)
"Using Novel Enzymes to Protect Against Organophosphorus Toxicity"
9:45 am - 9:55 amDiscussion
9:55 am - 10:20 amLate-Breaking Topic
10:20 am - 10:30 amDiscussion
10:30 am - 11:00 amCoffee Break
11:00 am - 11:25 amAndrew Pickett (Toxin Science Limited, USA)
"Botulinum Toxin - From Biothreat to Biomedicine"
11:25 am - 11:35 amDiscussion
11:35 am - 12:05 pmPamela Lein (University of California, Davis, USA)
"A Tale of Two Threat Agents: OPs and TETS"
12:05 pm - 12:15 pmDiscussion
12:15 pm - 12:30 pmPoster Previews
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session
6:00 pmDinner
7:30 pm - 9:30 pmMechanisms and Consequences of Host Immune Interactions with Emerging and Existing Threat Agents
Discussion Leader: Manuela Raffatellu (University of California, Irvine, USA)
7:30 pm - 7:45 pmIntroduction by Discussion Leader: Introduction and Perspectives on Host Immunity and Threat Agents
7:45 pm - 8:10 pmCarolyn Coyne (University of Pittsburgh, USA)
"Antimicrobial Signaling at the Maternal-Fetal Interface"
8:10 pm - 8:20 pmDiscussion
8:20 pm - 8:45 pmLate-Breaking Topic
8:45 pm - 8:55 pmDiscussion
8:55 pm - 9:20 pmTimothy Sampson (California Institute of Technology, USA)
"Alternative Roles for CRISPR-Cas Systems in Bacterial Pathogenesis"
9:20 pm - 9:30 pmDiscussion
Tuesday
7:30 am - 8:30 amBreakfast
8:30 amGroup Photo
9:00 am - 12:30 pmHost Barrier Function and Dysfunction
Discussion Leader: Catharine Bosio (Rocky Mountain Laboratories, NIH, USA)
9:00 am - 9:15 amIntroduction by Discussion Leader: Overview and Perspectives on the Influence of Threat Agents on Host Barriers
9:15 am - 9:45 amDebra Laskin (Rutgers University, USA)
"Inflammatory Mechanisms of Lung Injury Induced by Mustard Vesicants"
9:45 am - 9:55 amDiscussion
9:55 am - 10:20 amHarald Ott (Harvard Medical School, USA)
"Rebuilding the Damaged Lung"
10:20 am - 10:30 amDiscussion
10:30 am - 11:00 amCoffee Break
11:00 am - 11:25 amWilliam Beavers (Vanderbilt University, USA)
"Imaging Mass Spectrometry: Untargeted Molecular Histology at the Host-Pathogen Interface"
11:25 am - 11:35 amDiscussion
11:35 am - 12:05 pmWyndham Lathem (Institut Pasteur, France)
"Your Own Worst Enemy: How Yersinia pestis Turns the Body Against Itself"
12:05 pm - 12:15 pmDiscussion
12:15 pm - 12:30 pmPoster Previews
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session
6:00 pmDinner
7:30 pm - 9:30 pmTargeting Metabolism
Discussion Leader: Molly Hughes (University of Virginia, USA)
7:30 pm - 7:45 pmIntroduction by Discussion Leader: Overview and Perspectives on the the Targeting of Metabolism by Threat Agents
7:45 pm - 8:10 pmJean Challacombe (Los Alamos National Laboratory, USA)
"Metabolic Targets: Modeling and Predictions"
8:10 pm - 8:20 pmDiscussion
8:20 pm - 8:45 pmLate-Breaking Topic
8:45 pm - 8:55 pmDiscussion
8:55 pm - 9:20 pmMichael Lagunoff (University of Washington, USA)
"Targeting Viruses Through Cellular Metabolism"
9:20 pm - 9:30 pmDiscussion
Wednesday
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmExtended and Emerging Threats to Human Health and Security
Discussion Leader: Jacqueline Fletcher (Oklahoma State University, USA)
9:00 am - 9:15 amIntroduction by Discussion Leader: Perspectives and Overviews on Extended and Emerging Threats to Human Health and Security
9:15 am - 9:45 amWilliam Schneider (Foreign Disease Program, Agricultural Research Service, USDA, USA)
"CRISPR/Gene Grives: Potential Threats in Plants and Agriculture"
9:45 am - 9:55 amDiscussion
9:55 am - 10:25 amTownsend Peterson (University of Kansas, USA)
"From WMDs to CMBs: What Creative Malicious Biologists Could Do, but Haven't"
10:25 am - 10:35 amDiscussion
10:35 am - 11:05 amCoffee Break
11:05 am - 11:30 amLate-Breaking Topic
11:30 am - 11:40 amDiscussion
11:40 am - 12:05 pmTrevor Bedford (Fred Hutchinson Cancer Research Center, USA)
"Real-Time Genomic Surveillance of Pathogen Evolution and Spread"
12:05 pm - 12:15 pmDiscussion
12:15 pm - 12:30 pmPoster Previews
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session
6:00 pmDinner
7:00 pm - 7:30 pmBusiness Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
7:30 pm - 9:30 pmLate-Breaking Topics
Discussion Leader: Thomas Blake (Centers for Disease Control and Prevention, USA)
7:30 pm - 7:45 pmIntroduction by Discussion Leader: Perspectives on Emerging Threats and Challenges: A Perspective from the CDC
7:45 pm - 8:00 pmShort Talk Selected from Poster Abstracts
8:00 pm - 8:05 pmDiscussion
8:05 pm - 8:20 pmShort Talk Selected from Poster Abstracts
8:20 pm - 8:25 pmDiscussion
8:25 pm - 8:40 pmShort Talk Selected from Poster Abstracts
8:40 pm - 8:45 pmDiscussion
8:45 pm - 9:15 pmLate-Breaking Topic
9:15 pm - 9:30 pmDiscussion
Thursday
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmSmart Approaches for Detection, Prevention, and Intervention
Discussion Leader: Katrina Campbell (Queen's University Belfast, Ireland)
9:00 am - 9:15 amIntroduction by Discussion Leader: The Emergence of Smart Solutions to Threat Agents
9:15 am - 9:40 amEsther Chang (Georgetown University, USA)
"A Platform Technology Based on a Nanocomplex that Actively Crosses the Blood-Brain Barrier and Its Use in Medical Countermeasures Against Both Chemical and Biological Threat Agents"
9:40 am - 9:50 amDiscussion
9:50 am - 10:20 amPaula Hammond (Massachusetts Institute of Technology, USA)
"New Nano-Based Devices"
10:20 am - 10:30 amDiscussion
10:30 am - 11:00 amCoffee Break
11:00 am - 11:25 amRobert Meagher (Sandia National Laboratories, USA)
"You Catch More Flies (and Mosquitoes) with Honey - A New Approach to Automating Surveillance for Arboviruses"
11:25 am - 11:35 amDiscussion
11:35 am - 12:05 pmCharles Thompson (University of Montana, USA)
"Designer Chemical Probes for Advanced Imaging"
12:05 pm - 12:15 pmDiscussion
12:15 pm - 12:30 pmPoster Previews
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session
6:00 pmDinner
7:30 pm - 9:30 pmWorking at the Periphery: Bioengineering-Inspired Solutions for Counteracting Biological and Chemical Threats
Discussion Leader: Patrick Stayton (University of Washington, USA)
7:30 pm - 7:45 pmIntroduction by Discussion Leader: Perspectives and Overview of the Capacity of Bioengineering to Meet the Challenges and Opportunities Associated with Existing and Emerging Threats
7:45 pm - 8:10 pmNicole Steinmetz (Case Western Reserve University, USA)
"Nano-Inspired Vaccine Design"
8:10 pm - 8:20 pmDiscussion
8:20 pm - 8:45 pmBernhard Weigl (Global Good, Intellectual Ventures, USA)
"High Performance Lateral Flow Assays as First Line of Defense Against Bioagents"
8:45 pm - 8:55 pmDiscussion
8:55 pm - 9:20 pmDaniel Fletcher (University of California, Berkeley, USA)
"Dial 'P' for Pathogen"
9:20 pm - 9:30 pmDiscussion
Friday
7:30 am - 8:30 amBreakfast
9:00 amDeparture
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