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Aging, Biology of
Gordon Research Conference

Integrative Biology of Aging: New Insights from Molecules to Systems

Dates

July 9-14, 2017

Location

Les Diablerets Conference Center
Les Diablerets, Switzerland Site Information

Organizers

Chairs:
Adam Antebi & Shin-Ichiro Imai

Vice Chairs:
Thomas Rando & Marcia C. Haigis

Application Deadline

Applications for this meeting must be submitted by June 11, 2017. Please apply early, as some meetings become oversubscribed (full) before this deadline. If the meeting is oversubscribed, it will be stated here. Note: Applications for oversubscribed meetings will only be considered by the Conference Chair if more seats become available due to cancellations.

Meeting Description

The 2017 Gordon Research Conference (GRC) on the Biology of Aging will be held at the Les Diablerets Conference Center (Les Diablerets, Switzerland) on July 9-14, 2017, and the Gordon Research Seminar (GRS), which will be held at the same location on July 8-9, immediately prior to the GRC. The program has been developed around the theme of "Integrative Biology of Aging: New Insights from Molecules to Systems". Recent studies from diverse model organisms, such as worms, flies, and mice, have demonstrated that systemic interplay between multiple tissues and organs regulates aging and longevity. Additionally, subcellular systems such as organelles and stress pathways can often communicate intra- and intercellularly. To dissect such complex systemic regulation of aging and longevity, significant progress has been made in identifying control networks and basic architectures, but how communication is achieved at different levels of organization and assembled into larger architectures is only beginning to be explored. The dysfunction of critical components in these control networks contributes to the induction of the cellular and molecular hallmarks of aging, including mitochondrial dysfunction, epigenetic alterations, chronic inflammation, circadian rhythm dysfunction, genomic instability, loss of proteostasis, and others, and underlies diminished healthspan and lifespan. In the 2017 GRC, our major objective is to capture this new wave of the "integrative biology of aging", and further stimulate our thoughts and efforts to translate our knowledge into the development of effective interventions to achieve "productive aging", making the later years of our lives as healthy and productive as possible. The major objective of the GRS is to explore these themes in a supportive setting that particularly focuses on the needs of graduate students and postdoctoral trainees, and prepare them for a full and productive participation in the GRC to follow.

Related Meeting

This GRC will be held in conjunction with the "Aging, Biology of" Gordon Research Seminar (GRS). Those interested in attending both meetings must submit an application for the GRS in addition to an application for the GRC. Refer to the associated GRS program page for more information.

Contributors

Preliminary Program

The topics and speakers for the conference sessions are displayed below (italics denote discussion leaders). The Conference Chair is currently developing their detailed program, which will include the complete meeting schedule, as well as the talk titles for all speakers. The detailed program will be available by March 9, 2017. Please check back for updates.

  • Perspective: Integrative Biology of Aging
    (Gerald Shadel / Steve Horvath / Michael Hall / Pura Munoz-Canoves)
  • Fragility in Aging: Mitochondria and ER
    (Coleen Murphy / Sivan Henis-Korenblit / Gerald Shadel / Meng Wang)
  • Fragility in Aging: Epigenetics
    (Manuel Serrano / Masashi Narita / Andrew Yoo)
  • Perturbation: Inflammation, Metabolism, and Aging
    (Vera Gorbunova / Eiji Hara / Coleen Murphy / Tony Wyss-Coray)
  • Perturbation: Biological Rhythm and Aging
    (Steve Horvath / Jadwiga Giebultowicz / Akiko Satoh)
  • Robustness: Stress and Damage Responses
    (Malene Hansen / Vera Gorbunova / Manuel Serrano / Dario Valenzano)
  • Robustness: Proteostasis and Autophagy
    (Valter Longo / Anne Bertolotti / Malene Hansen)
  • Systemic Regulation of Aging and Longevity
    (Tony Wyss-Coray / Fabio Demontis / William Mair / Eline Slagboom)
  • Interventions for Productive Aging
    (Anne Bertolotti / Carles Canto / Dena Dubal / Valter Longo)
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