SUNDAY |
2:00 pm - 9:00 pm | Arrival and Check-in (Office Closed 6:00 pm - 7:00 pm) |
6:00 pm | Dinner |
7:30 pm - 7:35 pm | Welcome / Introductory Comments by GRC Site Staff |
7:35 pm - 9:30 pm | sRNA IN GAMETOGENESIS AND EMBRYOGENESIS |
7:35 pm - 7:45 pm | Discussion Leader: Haifan Lin (Yale) "Introduction" |
7:45 pm - 8:15 pm | Wei Yan (University of Nevada Reno)
"Roles of Testicular MicroRNAs" |
8:15 pm - 8:20 pm | Discussion |
8:20 pm - 8:50 pm | Deborah Bourc'his (Institute Curie)
"Epigenetic Cooperation in Transposon Suppression in the Male Germ Line" |
8:50 pm - 8:55 pm | Discussion |
8:55 pm - 9:25 pm | Haifan Lin (Yale)
"PIWI Proteins in Germline Stem Cell Division" |
9:25 pm - 9:30 pm | Discussion |
9:30 pm | Social |
MONDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | STEM CELLS: GERMLINE & EMBRYONIC |
9:00 am - 9:10 am | Discussion Leader: Erika Matunis (Hopkins) "Introduction" |
9:10 am - 9:40 am | Wolfgang Engel (University of Gottingen)
"From Stem Cells to Male Germ Cells" |
9:40 am - 9:45 am | Discussion |
9:45 am - 10:15 am | Kyle Orwig (University of Pittsburgh)
"Stem Cells in the Male Germline" |
10:15 am - 10:20 am | Discussion |
10:20 am - 11:00 am | Coffee Break / Group Photo |
11:00 am - 11:30 am | Michael Roberts (University of Missouri)
"The Transition from Human Embryonic Stem Cell to Trophoblast" |
11:30 am - 11:35 am | Discussion |
11:35 am - 11:50 am | Short Talk: Shau-Ping Lin (National Taiwan University)
"Genetic and epigenetic characterization of early germ cells isolated from ES cells via genetic selection" |
11:50 am - 11:55 am | Discussion |
11:55 am - 12:10 pm | Short Talk: Jiyoung Lee (Tokyo Medical and Dental University)
"Heritable imprinting defect caused by epigenetic abnormalities in spermatogonial stem cells" |
12:10 pm - 12:15 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session 1 |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | EPIGENETIC PROGRAMMING DURING GAMETOGENESIS AND EMBRYOGENESIS |
7:30 pm - 7:40 pm | Discussion Leader: John McCarrey (University Texas San Antonio) "Introduction" |
7:40 pm - 8:10 pm | Alex Meissner (Harvard)
"Genome-Wide Mapping of the Developing Stem Cell Epigenome" |
8:10 pm - 8:15 pm | Discussion |
8:15 pm - 8:45 pm | Gavin Kelsey (Babraham Institute)
"Mechanisms of gametic imprint mark establishment" |
8:45 pm - 8:50 pm | Discussion |
8:50 pm - 9:20 pm | Kevin Eggan (Harvard)
"Cell Biological Constraints on Reprogramming" |
9:20 pm - 9:25 pm | Discussion |
9:30 pm | Social |
TUESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | ASSISTED REPRODUCTIVE TECHNOLOGIES AND STEM CELLS |
9:00 am - 9:10 am | Discussion Leader: Carmen Sapienza (Temple University) "Introduction" |
9:10 am - 9:40 am | Derek McLean (Washington State University)
"Retinoic Acid Regulation of Spermatogonial Stem Cell Proliferation" |
9:40 am - 9:45 am | Discussion |
9:45 am - 10:15 am | Carmen Sapienza (Temple University)
"DNA Methylation and Gene Expression Differences in Children Conceived in Vitro Versus in Vivo" |
10:15 am - 10:20 am | Discussion |
10:20 am - 10:50 am | Coffee Break |
10:50 am - 11:20 am | Kevin Sinclair (University of Nottingham)
"Assisted Reproductive Techniques and Pregnancy Outcome" |
11:20 am - 11:25 am | Discussion |
11:25 am - 11:40 am | Short Talk: Eric De Waal (University Texas, San Antonio)
"Germline-specific epigenetic reprogramming in ICSI mice" |
11:40 am - 11:45 am | Discussion |
11:45 am - 12:05 pm | Short Talk: Mellissa Mann (University Western Ontario)
"Susceptibility of genomic imprinting to assisted reproductive technologies" |
12:05 pm - 12:10 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session 2 |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | INTEGRATED GENOMICS AND EPIGENETICS |
7:30 pm - 7:40 pm | Discussion Leader: Marisa S. Bartolomei (U Penn) "Introduction" |
7:40 pm - 8:10 pm | Minoo Rassoulzadegan (Inserm, Nice)
"Paramutation Mechanisms and Role in Development" |
8:10 pm - 8:15 pm | Discussion |
8:15 pm - 8:45 pm | Philippe Arnaud (CNRS Montpelllier FR)
"Germline-Dnmt3L independent acquisition of imprints in the mouse" |
8:45 pm - 8:50 pm | Discussion |
8:50 pm - 9:20 pm | Marisa S. Bartolomei (U Penn)
"Epigenetics and Imprinting Control Regions" |
9:20 pm - 9:25 pm | Discussion |
9:30 pm | Social |
WEDNESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | GONADAL DEVELOPMENT AND SEX DETERMINATION |
9:00 am - 9:10 am | Discussion Leader: Andrea Cupp (Nebraska) "Introduction" |
9:10 am - 9:40 am | Andrew Sinclair (Melbourne)
"Copy Number Variation Analysis of Patients With Disorders of Sexual Development: New Insights into Gonad Development and Dysfunction" |
9:40 am - 9:45 am | Discussion |
9:45 am - 10:15 am | David Page (Whitehead)
"Meiotic Initiation: How Germ Cells Decide to Go Haploid" |
10:15 am - 10:20 am | Discussion |
10:20 am - 10:50 am | Coffee Break |
10:50 am - 11:20 am | Blanche Capel (Duke)
"Battle of the Sexes: Patterning the Gonad" |
11:20 am - 11:25 am | Discussion |
11:25 am - 11:40 am | Short Talk: Sergei Tevosian (Dartmouth)
"Conditional Ablation of Gata4 and Fog2 Genes in Mice Reveals their Distinct Roles in Mammalian Sexual Differentiation" |
11:40 am - 11:45 am | Discussion |
11:45 am - 12:00 pm | Short Talk: Yukiko Yamazaki (Unversity Hawaii)
"Direct effect of retinoic acid on entry into meiosis in male germ cells" |
12:00 pm - 12:05 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 6:00 pm | Free Time |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | GENE NETWORKS AND TRANSCRIPTIONAL REGULATION |
7:30 pm - 7:40 pm | Discussion Leader: Miles Wilkinson (University California San Diego) "Introduction" |
7:40 pm - 8:10 pm | Bill Kelly (Emory University)
"Transcriptional Networks in Germ Cell Development" |
8:10 pm - 8:15 pm | Discussion |
8:15 pm - 8:45 pm | Miles Wilkinson (University of California at San Diego)
"Rhox Gene Networks" |
8:45 pm - 8:50 pm | Discussion |
8:50 pm - 9:20 pm | Andrew Kasarskis (Rosetta / Merck)
"Gene Network Identification in Development and Disease" |
9:20 pm - 9:25 pm | Discussion |
9:30 pm | Social |
THURSDAY |
7:30 am - 8:30 am | Breakfast |
8:30 am - 9:00 am | Business Meeting |
| (Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair) |
9:00 am - 12:30 pm | ENVIRONMENTAL IMPACTS ON EMBRYOGENESIS AND DEVELOPMENT |
9:00 am - 9:10 am | Discussion Leader: Pat Hunt (Washington State University) "Introduction" |
9:10 am - 9:40 am | Robert Waterland (Baylor College of Medicine)
"How Does Maternal Nutrition Affect Developmental Epigenetics in the Early Embryo?" |
9:40 am - 9:45 am | Discussion |
9:45 am - 10:15 am | Pat Hunt (Washington State University)
"Environmental Factors That Make a Good Egg Go Bad" |
10:15 am - 10:20 am | Discussion |
10:20 am - 10:50 am | Coffee Break |
10:50 am - 11:20 am | Emma Whitelaw (Queensland Inst, Australia)
"Environmental Effects on Epigenetic Programming" |
11:20 am - 11:25 am | Discussion |
11:25 am - 11:40 am | Short Talk: Dan Rappolee (Wayne State)
"Stress and stress enzymes cause developmental and homeostatic effects in embryos and stem cells" |
11:40 am - 11:45 am | Discussion |
11:45 am - 12:00 pm | Short Talk: Carlos Guerrero-Bosagna (Washington State University)
"Epigenetic transgenerational actions of the endocrine disruptor vinclozolin on the rat male germ line" |
12:00 pm - 12:05 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 6:00 pm | Free Time |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | FOUNDER'S FORUM / KEYNOTE LECTURES |
| Discussion Leader: MaryAnn Handel (Jackson Lab) |
7:30 pm - 8:00 pm | Eva Eicher (Jackson Lab)
"Genetics and Sex Determination" |
8:00 pm - 8:10 pm | Discussion |
8:10 pm - 8:40 pm | Janet Rossant (University of Toronto)
"From Embryo to Stem Cell and Back Again" |
8:40 pm - 8:50 pm | Discussion |
8:50 pm - 9:20 pm | John Eppig (Jackson Lab)
"Role of the Egg in the Ovary and Development" |
9:20 pm - 9:30 pm | Discussion |
9:30 pm | Social |
FRIDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am | Depart |