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Signaling by Adhesion Receptors (GRS)
Gordon Research Seminar

Outside-In and Inside-Out: Adhesion Signaling from Cells to Systems

Dates

June 18-19, 2016

Location

Bates College
Lewiston, ME

Organizers

Chairs:
Madeleine J. Oudin & Nisha Mohd Rafiq

Meeting Description

The Gordon Research Seminar on Signaling by Adhesion Receptors is a unique forum for graduate students, post-docs, and other scientists with comparable levels of experience and education to present and exchange new data and cutting edge ideas.

This meeting will focus on how adhesion receptors allow cells to interact with and integrate signals from their environment, drawing from diverse fields including cell and developmental biology, bioengineering, biophysics, biomedical research and systems biology. This GRS will not only provide an outstanding opportunity for graduate students and post-docs to present their work, receive constructive feedback, network with each other and discuss career opportunities in biomedical research, but it will also prepare attendees for the subsequent GRC, facilitating higher levels of student participation and leadership throughout the GRC.

Related Meeting

This GRS was held in conjunction with the "Signaling by Adhesion Receptors" Gordon Research Conference (GRC). Refer to the associated GRC program page for more information.

Contributors

Final Meeting Program

Saturday
2:00 pm - 5:00 pmArrival and Check-in
3:30 pm - 3:45 pmIntroductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair
3:45 pm - 4:30 pmKeynote Session: New Frontiers in Adhesion Signaling
Discussion Leader: Madeleine Oudin (Massachusetts Institute of Technology, USA)
3:45 pm - 4:20 pmAlexandra Naba (Massachusetts Institute of Technology, USA)
"Tumor Progression Is a Question of Context! Exploring and Exploiting the Extracellular Matrix and Cell-Matrix Interactions for Diagnosing and Treating Cancers"
4:20 pm - 4:30 pmDiscussion
4:30 pm - 6:00 pmPoster Session
6:00 pmDinner
7:30 pm - 9:30 pmCell-Based Regulation of Adhesion Signaling and Dynamics
Discussion Leader: Guillaume Jacquemet (University of Turku, Finland)
7:30 pm - 7:45 pmBo Yang (Mechanobiology Institute, National University of Singapore, Singapore)
"Mechanosensing Cell Contractions Controlled by Associated Tyrosine Kinases"
7:45 pm - 7:55 pmDiscussion
7:55 pm - 8:10 pmVinay Swaminathan (National Heart, Lung, and Blood Institute, NIH, USA)
"Actin Retrograde Flow Orients and Aligns Activated, Ligand-Engaged Integrins in Focal Adhesions"
8:10 pm - 8:20 pmDiscussion
8:20 pm - 8:35 pmMegan Novak (Northwestern University, USA)
"AlphaE-Catenin Homodimers Are Recruited to the Cell Periphery and Promote Cell-Cell Contact"
8:35 pm - 8:45 pmDiscussion
8:45 pm - 9:00 pmDennis Zhou (Georgia Institute of Technology, USA)
"Force-Signaling Coupling at Cell Adhesive Structures"
9:00 pm - 9:10 pmDiscussion
9:10 pm - 9:25 pmAlison Wirshing (Northeastern University, USA)
"Development of Organized Stress Fibers in a Model Contractile Tube Coincides with Cell Contraction Following Tissue Stretch and Is Dependent on Ca2+ Signaling and Myosin II Activity"
9:25 pm - 9:30 pmDiscussion
Sunday
7:30 am - 8:30 amBreakfast
9:00 am - 11:00 amSystems-Level Role of Adhesion in Development and Disease
Discussion Leader: Vinay Swaminathan (National Heart, Lung, and Blood Institute, NIH, USA)
9:00 am - 9:15 amKlaudia Schossleitner (Medical University of Vienna, Austria)
"Cingulin Regulates Endothelial Barrier Function via Junctional RhoGEFs"
9:15 am - 9:25 amDiscussion
9:25 am - 9:40 amJohanna Lilja (University of Turku, Finland)
"SHANK3 Structure Reveals a Ras-Associated Domain Regulating Integrin Activation"
9:40 am - 9:50 amDiscussion
9:50 am - 10:05 amCarlos Perez Gonzalez (Institute of Bioengineering of Catalonia, Spain)
"E-Cadherin Regulates Epithelial Contractility and Active De-Wetting"
10:05 am - 10:15 amDiscussion
10:15 am - 10:30 amWhitney Stoppel (Tufts University, USA)
"Composite Silk-Cardiac Extracellular Matrix Patches for Applications in Heart Disease"
10:30 am - 10:40 amDiscussion
10:40 am - 10:55 amMagdalene Michael (King's College London, United Kingdom)
"Dissecting the Functional Interplay Between Kindlin1, β1 Integrins and EGFR in Human Keratinocytes"
10:55 am - 11:00 amDiscussion
11:00 am - 12:30 pmPoster Session

Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pmLunch
1:30 pm - 2:30 pmMentorship Component: Career Options After Academia
Discussion Leader: Nisha Mohd Rafiq (National University of Singapore, Singapore)
1:30 pm - 2:30 pmPanel Discussion
"Transitioning from Your PhD/Post-Doc: Opportunities for Scientists Inside and Outside of Academia"
  • Ann Cheung (Equipoise Therapeutics, USA)
  • Danielle Day (AstraZeneca, USA)
  • Ann Miller (University of Michigan, USA)
2:30 pm - 3:00 pmEvaluation Period
Fill in GRS Evaluation Forms
3:00 pmSeminar Concludes
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