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Angiogenesis (GRS)
Gordon Research Seminar

Molecular Signals, Mechanical Forces and Dynamic Behaviors Guiding Angiogenesis

Dates

August 5-6, 2017

Location

Salve Regina University
Newport, RI

Organizers

Chairs:
Emma J. Gordon & Anne Karine Lagendijk

Meeting Description

The Gordon Research Seminar on Angiogenesis is a unique forum for graduate students, post-docs, and other scientists with comparable levels of experience and education to present and exchange new data and cutting edge ideas.

The 2017 Angiogenesis GRS will focus on recent advances in the mechanisms of endothelial cell specification, differentiation and dynamic migratory behaviour required to build and maintain blood vessels. Endothelial cells are able to integrate and co-ordinate a range of extra-cellular, intra-cellular and inter-cellular signals to form a functional vascular network. The aim of this meeting is to present and discuss the most recent findings in these processes using a range of innovative in vivo and in vitro models. The meeting will also include an open panel discussion on career development from senior scientists at different career stages.

Related Meeting

This GRS was held in conjunction with the "Angiogenesis" Gordon Research Conference (GRC). Refer to the associated GRC program page for more information.

Contributors

Meeting Program

Saturday
2:00 pm - 5:00 pmArrival and Check-in
3:30 pm - 3:45 pmIntroductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair
3:45 pm - 4:30 pmKeynote Session: Endothelial Cell Specification and Differentiation
Discussion Leader: Anne Karine Lagendijk (Institute for Molecular Biology, University of Queensland, Australia)
3:45 pm - 4:05 pmDidier Stainier (Max Planck Institute for Heart and Lung Research, Germany)
"Endothelial Cell Development in Zebrafish"
4:05 pm - 4:15 pmDiscussion
4:15 pm - 4:25 pmAlice Neal (University of Oxford, United Kingdom)
"Vein Identity Requires BMP Signalling"
4:25 pm - 4:30 pmDiscussion
4:30 pm - 6:00 pmPoster Session
6:00 pmDinner
7:30 pm - 9:30 pmAngiogenesis, Metabolism and Disease / Keynote Session: Vascular Patterning
Discussion Leaders: Katie Bentley (Boston University, USA / Uppsala University, Sweden) and David Kallenberg (Institute of Ophthalmology, University College London, United Kingdom)
7:30 pm - 7:40 pmRobert Johnson (University of East Anglia, United Kingdom)
"Regulating Post-Natal Retinal Angiogenesis: A Fresh Look at the Roles of avβ3 and a5β1 Integrins"
7:40 pm - 7:45 pmDiscussion
7:45 pm - 7:55 pmJoanna Kalucka (Vesalius Research Centre (VRC), VIB-KU Leuven, Belgium)
"Quiescent Endothelial Cells Upregulate Fatty Acid β-Oxidation for Vasculoprotection via Redox Homeostasis"
7:55 pm - 8:00 pmDiscussion
8:00 pm - 8:10 pmMasataka Yokoyama (Weill Cornell Medicine, USA)
"Endothelial p53 Prevents the Aging Stress-Induced Adipose Tissue Malignancy"
8:10 pm - 8:15 pmDiscussion
8:15 pm - 8:25 pmAlexandre Dubrac (Yale University, USA)
"Inhibiting Nck-Dependent Pericyte Migration Improves Pathological Neoangiogenesis During Retinopathy"
8:25 pm - 8:30 pmDiscussion
8:30 pm - 8:40 pmHeike Stingl (Institute for Vascular Signalling, Goethe University Frankfurt, Germany)
"The Role of AMP-Activated Protein Kinase a1 in Angiogenesis"
8:40 pm - 8:45 pmDiscussion
8:45 pm - 8:55 pmMarc Schwab (University of Zurich, Switzerland)
"Nogo-A and S1PR2 as Novel Regulators of Developmental and Tumor Angiogenesis in the CNS"
8:55 pm - 9:00 pmDiscussion
9:00 pm - 9:20 pmAnne Eichmann (Yale School of Medicine, USA)
"Vascular Patterning in Development and Disease"
9:20 pm - 9:30 pmDiscussion
Sunday
7:30 am - 8:30 amBreakfast
9:00 am - 11:00 amNovel Methods to Study Angiogenesis / Vascular Integrity and Permeability
Discussion Leaders: Michael Potente (Max Planck Institute for Heart and Lung Research, Germany) and Georgia Zarkada (Yale University, USA)
9:00 am - 9:10 amAkanksha Bhargava (Johns Hopkins University, USA)
"High-Fidelity Image-Based Modeling of Structural and Functional Angiogenic Heterogeneity in Breast Cancer"
9:10 am - 9:15 amDiscussion
9:15 am - 9:25 amH.H. Greco Song (Massachusetts Institute of Technology, USA)
"Synthetic Functional Vasculature as an Organ-on-a-Chip Platform"
9:25 am - 9:30 amDiscussion
9:30 am - 9:40 amSerena Zacchigna (International Center for Genetic Engineering and Biotechnology, Italy)
"Understanding the Poor Angiogenic Capacity of the Mammalian Heart"
9:40 am - 9:45 amDiscussion
9:45 am - 9:55 amDavid Gurevich (University of Bristol, United Kingdom)
"Live Imaging of Wound Angiogenesis Reveals How Phenotypic State of Macrophages Directs Vessel Sprouting and Subsequent Vessel Resolution"
9:55 am - 10:00 amDiscussion
10:00 am - 10:10 amBongnam Jung (Uppsala University, Sweden)
"The Role of FGFBP1 in the Central Nervous System"
10:10 am - 10:15 amDiscussion
10:15 am - 10:25 amSinem Karaman (Wihuri Research Institute, Finland)
"Interplay of VEGFRs in the Regulation of Vascular Permeability"
10:25 am - 10:30 amDiscussion
10:30 am - 10:40 amRoss Smith (Uppsala University, Sweden)
"Vascular Permeability via VEGF/VEGFR2 Contributes to Pathological Angiogenesis in the Eye"
10:40 am - 10:45 amDiscussion
10:45 am - 10:55 amNicolas Ricard (Yale Cardiovascular Research Center, USA)
"ERK1/2 Pathway Is Critical for Maintenance of Vascular Integrity"
10:55 am - 11:00 amDiscussion
11:00 am - 12:30 pmPoster Session

Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pmLunch
1:30 pm - 2:30 pmMentorship Component: Career Panel
Discussion Leader: Anne Eichmann (Yale School of Medicine, USA)
1:30 pm - 2:30 pmPanel Discussion
"Career Development"
  • Katie Bentley (Boston University, USA / Uppsala University, Sweden)
  • Michael Potente (Max Planck Institute for Heart and Lung Research, Germany)
  • Didier Stainier (Max Planck Institute for Heart and Lung Research, Germany)
  • Roberto Buccione (EMBO Molecular Medicine, EMBO Press, Germany)
2:30 pm - 3:00 pmEvaluation Period
Fill in GRS Evaluation Forms
3:00 pmSeminar Concludes

Research reported in this publication was supported by the National Institute Of Allergy And Infectious Diseases of the National Institutes of Health under Award Number R13AI131445. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.
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