Gordon Research Conferences
Meeting Details

Calcium Signalling (GRS)
Gordon Research Seminar

Intracellular Calcium Signalling in Normal Physiology and Disease


June 17-18, 2017


Renaissance Tuscany Il Ciocco
Lucca (Barga), Italy


Galina Schmunk & Andrew D. James

Meeting Description

The Gordon Research Seminar on Calcium Signalling is a unique forum for graduate students, post-docs, and other scientists with comparable levels of experience and education to present and exchange new data and cutting edge ideas. The aim of this Gordon Research Seminar is to bring together students, postdocs and junior investigators in the field of calcium signaling to share cutting-edge research and to create opportunities for future collaborations.

Topics of discussion in scientific sessions include structure and function of calcium signaling molecules and components, and advances in understanding calcium signaling and the associated changes in physiology and disease. The focus of this meeting is to provide young scientists with an inviting forum for the exchange and discussion of primarily new/unpublished data on intracellular calcium signaling.

Related Meeting

This GRS was held in conjunction with the "Calcium Signalling" Gordon Research Conference (GRC). Refer to the associated GRC program page for more information.


Meeting Program

1:30 pm - 4:30 pmArrival and Check-in
3:00 pm - 3:15 pmIntroductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair
3:15 pm - 4:00 pmKeynote Session: The Road to Discovery of MCU
Discussion Leader: Galina Schmunk (University of California, Irvine, USA)
3:15 pm - 3:50 pmRosario Rizzuto (University of Padova, Italy)
"The Road to Discovery of MCU"
3:50 pm - 4:00 pmDiscussion
4:00 pm - 5:30 pmPoster Session
5:30 pm - 7:30 pmRole of Ca2+ Signaling in Disease and Therapy
Discussion Leaders: Andrew Thomas (Rutgers University, USA) and Crystal Archer (University of Texas Health Science Center at San Antonio, USA)
5:30 pm - 5:45 pmDaniela Arduino (Gene Center Munich, Germany)
"An Orthogonal Yeast-Mammalian Chemical Screen Identifies DA2801 as a Novel Inhibitor of the Mitochondrial Ca2+ Uniporter"
5:45 pm - 5:50 pmDiscussion
5:50 pm - 6:05 pmMiryam Hortua Triana (Center for Tropical and Emerging Global Diseases, University of Georgia, USA)
"Two Mechanisms of Ca2+ Entry in Toxoplasma gondii, Each with Specific Roles in Virulence Pathways"
6:05 pm - 6:10 pmDiscussion
6:10 pm - 6:25 pmPawel Ferdek (Cardiff University, United Kingdom)
"BH3 Mimetic-Elicited Ca2+ Signals in Pancreatic Acinar Cells Are Dependent on Bax and Can Be Reduced by Ca2+-Like Peptides"
6:25 pm - 6:30 pmDiscussion
6:30 pm - 6:45 pmPishyaporn Sritangos (University of Manchester, United Kingdom)
"The Role of PMCA4 in Pancreatic Cancer"
6:45 pm - 6:50 pmDiscussion
6:50 pm - 7:05 pmKetaki Mhatre (Charité Campus Virchow-Klinikum, Germany)
"Crosstalk Between FGF23 and Angiotensin II Mediated Ca2+-Dependent Signaling in Cardiac Hypertrophy"
7:05 pm - 7:10 pmDiscussion
7:10 pm - 7:25 pmIman Azimi (The University of Queensland, Australia)
"TRPC1 Regulates Hypoxia Associated Events in PTEN-Deficient Breast Cancer Cells"
7:25 pm - 7:30 pmDiscussion
8:00 pmDinner
7:30 am - 8:30 amBreakfast
9:00 am - 11:00 amFine-Tuning Ca2+ Signaling: Channels, Transporters, and Ca2+-Binding Proteins / Mentorship Component: Navigating Conference Networking
Discussion Leaders: Gary St. John Bird (National Institute of Environmental Health Sciences, NIH, USA) and Radhika Khandelwal (Centre for Cellular and Molecular Biology, India)
9:00 am - 9:15 amRahul Banerjee (Johns Hopkins University School of Medicine, USA)
"Bilobal Architecture of Calmodulin in L-Type Ca2+ Channel Regulation"
9:15 am - 9:20 amDiscussion
9:20 am - 9:35 amChristina Go (Lewis Katz School of Medicine, Temple University, USA)
"Competitive POST/STIM1-Dependent Mechanisms Controlling PMCA4 Function During T Cell Activation"
9:35 am - 9:40 amDiscussion
9:40 am - 9:55 amEhsan Kheradpezhouh (Australian National University, Australia)
"TRPA1 Expression and Its Functional Activation in Rodent Cortex"
9:55 am - 10:00 amDiscussion
10:00 am - 10:15 amCrystal Archer (University of Texas Health Science Center at San Antonio, USA)
"A Possible Structural Mechanism of Phosphorylation in Mediating Crosstalk Between Calmodulin and PIP2 on KCNQ4 K+ Ion Channels"
10:15 am - 10:20 amDiscussion
10:20 am - 10:50 amJulia Gerasimenko (School of Biosciences, Cardiff University, United Kingdom)
"Successful Conference Networking and Academic Career Development"
10:50 am - 11:00 amDiscussion
11:00 am - 12:30 pmPoster Session

Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pmLunch
1:30 pm - 2:30 pmAdvances in Store-Operated Ca2+ Entry
Discussion Leaders: Aparna Gudlur (La Jolla Institute for Allergy and Immunology, USA) and Emma McIvor (University of Nottingham, United Kingdom)
1:30 pm - 1:45 pmPriscilla Yeung (Northwestern University, USA)
"Interactions Between Transmembrane Helices in ORAI1 Regulate STIM1-Mediated Activation"
1:45 pm - 1:50 pmDiscussion
1:50 pm - 2:05 pmNiroj Shrestha (Medical University of Graz, Austria)
"TRIC Channels Govern Frequency of Oscillatory Ca2+ Signals by Interference with STIM-Orai Ca2+ Entry Machinery"
2:05 pm - 2:10 pmDiscussion
2:10 pm - 2:25 pmMonica Bulla Didier (University of Geneva, Switzerland)
"ORAI1 Mutations with Distinct Channel Gating Defects Linked to Tubular Aggregate Myopathy"
2:25 pm - 2:30 pmDiscussion
2:30 pm - 3:00 pmEvaluation Period
Fill in GRS Evaluation Forms
3:00 pmSeminar Concludes

Research reported in this publication was supported by the National Institute of Allergy and Infectious Diseases of the National Institutes of Health under Award Number 1R13Al131591-01. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.
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