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Calcium Signalling (GRS)
Gordon Research Seminar

Intracellular Calcium Signalling in Normal Physiology and Disease

Dates

June 17-18, 2017

Location

Renaissance Tuscany Il Ciocco
Lucca (Barga), Italy Site Information

Organizers

Chairs:
Galina Schmunk & Andrew D. James

Application Deadline

Applications for this meeting must be submitted by May 20, 2017. Please apply early, as some meetings become oversubscribed (full) before this deadline. If the meeting is oversubscribed, it will be stated here. Note: Applications for oversubscribed meetings will only be considered by the Conference Chair if more seats become available due to cancellations.

GRS Speaker Abstract Deadline: Although applications will be accepted until the date noted above, any applicants who wish to be considered for an oral presentation should submit their application by March 17, 2017. Please refer to the application instructions in the Meeting Description section below for more details (if available).

Meeting Description

Overview

The Gordon Research Seminar on Calcium Signalling is a unique forum for graduate students, post-docs, and other scientists with comparable levels of experience and education to present and exchange new data and cutting edge ideas. The aim of this Gordon Research Seminar is to bring together students, postdocs and junior investigators in the field of calcium signaling to share cutting-edge research and to create opportunities for future collaborations.

Topics of discussion in scientific sessions include structure and function of calcium signaling molecules and components, and advances in understanding calcium signaling and the associated changes in physiology and disease. The focus of this meeting is to provide young scientists with an inviting forum for the exchange and discussion of primarily new/unpublished data on intracellular calcium signaling.

Application Instructions

The meeting will feature approximately 10 talks and 2 poster sessions. All attendees are expected to actively participate in the GRS either by giving an oral presentation or presenting a poster. Therefore, all applications must include an abstract.

The Chairs will select speakers from abstracts submitted by March 17, 2017. Those applicants who are not chosen for talks and those who apply after the deadline to be considered for an oral presentation will be expected to present a poster. In order to participate, you must submit an application by the date indicated in the Application Deadline section above.

Related Meeting

This GRS will be held in conjunction with the "Calcium Signalling" Gordon Research Conference (GRC). Those interested in attending both meetings must submit an application for the GRC in addition to an application for the GRS. Refer to the associated GRC program page for more information.

Contributors

Meeting Program

Saturday
1:30 pm - 4:30 pmArrival and Check-in
3:00 pm - 3:15 pmIntroductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair
3:15 pm - 4:00 pmKeynote Session: The Road to Discovery of MCU
Discussion Leader: Galina Schmunk (University of California, Irvine, USA)
3:15 pm - 3:50 pmRosario Rizzuto (University of Padova, Italy)
"The Road to Discovery of MCU"
3:50 pm - 4:00 pmDiscussion
4:00 pm - 5:30 pmPoster Session
5:30 pm - 7:30 pmRole of Ca2+ Signaling in Disease and Therapy
Discussion Leaders: Andrew Thomas (Rutgers University, USA) and Rajender Motiani (CSIR-Institute of Genomics and Integrative Biology, India)
5:30 pm - 5:45 pmDaniela Arduino (Gene Center Munich, Germany)
"An Orthogonal Yeast-Mammalian Chemical Screen Identifies DA2801 as a Novel Inhibitor of the Mitochondrial Ca2+ Uniporter"
5:45 pm - 5:50 pmDiscussion
5:50 pm - 6:05 pmMiryam Hortua Triana (Center for Tropical and Emerging Global Diseases, University of Georgia, USA)
"Two Mechanisms of Ca2+ Entry in Toxoplasma gondii, Each with Specific Roles in Virulence Pathways"
6:05 pm - 6:10 pmDiscussion
6:10 pm - 6:25 pmPawel Ferdek (Cardiff University, United Kingdom)
"BH3 Mimetic-Elicited Ca2+ Signals in Pancreatic Acinar Cells Are Dependent on Bax and Can Be Reduced by Ca2+-Like Peptides"
6:25 pm - 6:30 pmDiscussion
6:30 pm - 6:45 pmPishyaporn Sritangos (University of Manchester, United Kingdom)
"The Role of PMCA4 in Pancreatic Cancer"
6:45 pm - 6:50 pmDiscussion
6:50 pm - 7:05 pmKetaki Mhatre (Charité Campus Virchow-Klinikum, Germany)
"Crosstalk Between FGF23 and Angiotensin II Mediated Ca2+-Dependent Signaling in Cardiac Hypertrophy"
7:05 pm - 7:10 pmDiscussion
7:10 pm - 7:25 pmIman Azimi (The University of Queensland, Australia)
"TRPC1 Regulates Hypoxia Associated Events in PTEN-Deficient Breast Cancer Cells"
7:25 pm - 7:30 pmDiscussion
8:00 pmDinner
Sunday
7:30 am - 8:30 amBreakfast
9:00 am - 11:00 amFine-Tuning Ca2+ Signaling: Channels, Transporters, and Ca2+-Binding Proteins / Mentorship Component: Navigating Conference Networking
Discussion Leaders: Gary St. John Bird (National Institute of Environmental Health Sciences, NIH, USA) and Radhika Khandelwal (Centre for Cellular and Molecular Biology, India)
9:00 am - 9:15 amRahul Banerjee (Johns Hopkins University School of Medicine, USA)
"Bilobal Architecture of Calmodulin in L-Type Ca2+ Channel Regulation"
9:15 am - 9:20 amDiscussion
9:20 am - 9:35 amChristina Go (Lewis Katz School of Medicine, Temple University, USA)
"Competitive POST/STIM1-Dependent Mechanisms Controlling PMCA4 Function During T Cell Activation"
9:35 am - 9:40 amDiscussion
9:40 am - 9:55 amEhsan Kheradpezhouh (Australian National University, Australia)
"TRPA1 Expression and Its Functional Activation in Rodent Cortex"
9:55 am - 10:00 amDiscussion
10:00 am - 10:15 amCrystal Archer (University of Texas Health Science Center at San Antonio, USA)
"A Possible Structural Mechanism of Phosphorylation in Mediating Crosstalk Between Calmodulin and PIP2 on KCNQ4 K+ Ion Channels"
10:15 am - 10:20 amDiscussion
10:20 am - 10:50 amJulia Gerasimenko (School of Biosciences, Cardiff University, United Kingdom)
"Successful Conference Networking and Academic Career Development"
10:50 am - 11:00 amDiscussion
11:00 am - 12:30 pmPoster Session

Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pmLunch
1:30 pm - 2:30 pmAdvances in Store-Operated Ca2+ Entry
Discussion Leaders: Aparna Gudlur (La Jolla Institute for Allergy and Immunology, USA) and Emma McIvor (University of Nottingham, United Kingdom)
1:30 pm - 1:45 pmPriscilla Yeung (Northwestern University, USA)
"Interactions Between Transmembrane Helices in ORAI1 Regulate STIM1-Mediated Activation"
1:45 pm - 1:50 pmDiscussion
1:50 pm - 2:05 pmNiroj Shrestha (Medical University of Graz, Austria)
"TRIC Channels Govern Frequency of Oscillatory Ca2+ Signals by Interference with STIM-Orai Ca2+ Entry Machinery"
2:05 pm - 2:10 pmDiscussion
2:10 pm - 2:25 pmMonica Bulla Didier (University of Geneva, Switzerland)
"ORAI1 Mutations with Distinct Channel Gating Defects Linked to Tubular Aggregate Myopathy"
2:25 pm - 2:30 pmDiscussion
2:30 pm - 3:00 pmEvaluation Period
Fill in GRS Evaluation Forms
3:00 pmSeminar Concludes
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