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Collagen (GRS)
Gordon Research Seminar

Collagen Biochemistry to Physiology: Relevance to Living Tissues and Exploitation in Medical Technologies

Dates

July 15-16, 2017

Location

Colby-Sawyer College
New London, NH

Organizers

Chairs:
Celestial Jones-Paris & Richard L. Williams

Meeting Description

The Gordon Research Seminar (GRS) on Collagen is a unique forum for graduate students, post-docs, and other scientists with comparable levels of experience and education to present and exchange new data and cutting edge ideas.

The focus of the 2017 GRS on Collagen is to provoke discussion and collaboration of interdisciplinary approaches to collagen research amongst the emerging generation of investigators advancing our understanding through discoveries. Featured presentations of innovative studies will be selected by the GRS chairs. Poster and program session presentation topics will include, but are not limited to, regulation of collagen expression, biochemical aspects of collagen assembly, roles of collagens in cell biology, biotechnologies, and clinical applications. Invited senior scientists will be present during discussion sessions to advocate new ideas and provide experienced suggestions as needed. Additionally, a keynote lecture will be presented by a distinguished investigator of collagen at the meeting. All attendees of the 2017 GRS on Collagen are encouraged to attend the 2017 Gordon Research Conference (GRC) on Collagen that follows which will host world-renowned collagen researchers and additional advances will be discussed. These two conferences will be held at Colby-Sawyer College in New London, NH surrounded by serene mountainous views. Outdoor excursions and on-site sports facilities will be available for adventures and recreations. The 2017 GRS on Collagen will be an atmosphere to build professional confidence, engage in scientific discussions, and enjoy camaraderie among peers.

Related Meeting

This GRS was held in conjunction with the "Collagen" Gordon Research Conference (GRC). Refer to the associated GRC program page for more information.

Contributors

Meeting Program

Saturday
2:00 pm - 5:00 pmArrival and Check-in
3:30 pm - 3:45 pmIntroductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair
3:45 pm - 4:30 pmKeynote Session: The Molecular and Fibril Structure of Collagen: The Role of Periodicity
Discussion Leader: Richard Williams (University of Birmingham, United Kingdom)
3:45 pm - 4:20 pmMelinda Duer (University of Cambridge, United Kingdom)
"The Molecular and Fibril Structure of Collagen: The Role of Periodicity"
4:20 pm - 4:30 pmDiscussion
4:30 pm - 6:00 pmPoster Session
6:00 pmDinner
7:30 pm - 9:30 pmCollagens Expression and Molecular Intricacies in Cell Microenvironments as Drivers of Cell Biology
Discussion Leaders: Nicholas Kaiser (Brown University, USA) and Agnes Tessier (Université Claude Bernard Lyon 1, France)
7:30 pm - 7:45 pmCharlotte Gistelinck (University of Washington, USA)
"Phenomic Analysis of Zebrafish Type I Collagen Mutants Reveals a Spectrum of Skeletal Phenotypes Mimicking the Clinical Variability in Human Brittle Bone Disease"
7:45 pm - 7:50 pmDiscussion
7:50 pm - 8:05 pmHerimela Solomon-Degefa (Center for Biochemistry, University of Cologne, Germany)
"Structural Characterization of Collagen VI von Willebrand Factor Type A Domains and the Functional Consequences of Mutations"
8:05 pm - 8:10 pmDiscussion
8:10 pm - 8:25 pmPauline Nauroy (Institut de Génomique Fonctionnelle de Lyon (IGLF), Ecole Normale Superieure de Lyon, France)
"Collagen XIV as a New Regulator of Basement Membrane Biomechanics During Zebrafish Caudal Fin Regeneration"
8:25 pm - 8:30 pmDiscussion
8:30 pm - 8:45 pmJade Gumbs (University of Liverpool, United Kingdom)
"Impact of Ageing on TGF-β Stimulated Type I Collagen Production"
8:45 pm - 8:50 pmDiscussion
8:50 pm - 9:05 pmRicha Garva (United Kingdom)
"Circadian Clock Regulation of the Secretory Pathway in Fibroblasts"
9:05 pm - 9:10 pmDiscussion
9:10 pm - 9:30 pmGeneral Discussion
Sunday
7:30 am - 8:30 amBreakfast
9:00 am - 11:00 amCollagens as Clinical Targets and Emerging Clinical Technologies
Discussion Leaders: Yang Li (University of Utah, USA) and Pauline Nauroy (Institut de Génomique Fonctionnelle de Lyon (IGLF), Ecole Normale Superieure de Lyon, France)
9:00 am - 9:15 amRui Li (University of Cambridge, United Kingdom)
"Diabetes: Roles of Collagen and Sugar in Tissue and Organ Damage"
9:15 am - 9:20 amDiscussion
9:20 am - 9:35 amDelfien Syx (Ghent University, Belgium)
"Pain-Related Phenotypes in a Murine Model for Classical Ehlers-Danlos Syndrome"
9:35 am - 9:40 amDiscussion
9:40 am - 9:55 amLucas Bennink (University of Utah, USA)
"Next-Generation Collagen Hybridizing Peptides as Theranostic Probes: The Use of Non-Natural Amino Acids to Prevent Self-Trimerization"
9:55 am - 10:00 amDiscussion
10:00 am - 10:15 amEssak Khan (INM - Leibniz Institute for New Materials, Germany)
"Photoactivatable Hsp47: An Optogenetic Tool to Control and Regulate Collagen Assembly and Tumor Microenvironment"
10:15 am - 10:20 amDiscussion
10:20 am - 10:35 amNicholas Kaiser (Brown University, USA)
"An Anisotropic Collagen Microfiber and Hydrogel Composite Scaffold for Cardiac Tissue Engineering"
10:35 am - 10:40 amDiscussion
10:40 am - 11:00 amGeneral Discussion
11:00 am - 12:30 pmPoster Session

Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pmLunch
1:30 pm - 2:30 pmMentorship Component: Career Panel
Discussion Leaders: Wing Ying Chow (Leibniz-Forschungsinstitut für Molekulare Pharmakologie, Germany) and Celestial Jones-Paris (Vanderbilt University Medical Center, USA)
1:30 pm - 2:25 pmPanel Discussion
"Lessons from My Journey of Doctoral Training and Their Influence on My Career"
  • John Bateman (Murdoch Childrens Research Institute, Australia)
  • Melinda Duer (University of Cambridge, United Kingdom)
  • Joseph Freeman (Rutgers University, USA)
  • Sufi M. Thomas (University of Kansas Medical Center, USA)
2:25 pm - 2:30 pmClosing Remarks
2:30 pm - 3:00 pmEvaluation Period
Fill in GRS Evaluation Forms
3:00 pmSeminar Concludes

Funding for this conference was made possible by the National Institute of Arthritis and Musculoskeletal and Skin Disease (NIAMS). The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention by trade names, commercial practices, or organizations imply endorsement by the U.S. Government.
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