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Chemotactic Cytokines (GRS)
Gordon Research Seminar

Emerging Concepts in Chemokine Biology

Dates

May 28-29, 2016

Location

PGA Catalunya Business and Convention Centre
Girona, Spain

Organizers

Chairs:
Maud Deruaz & Douglas P. Dyer

Meeting Description

The Gordon Research Seminar on Chemotactic Cytokines is a unique forum for graduate students, post-docs, and other scientists with comparable levels of experience and education to present and exchange new data and cutting edge ideas.

The focus of this meeting is to present cutting edge, unpublished research on chemokine activities at the molecular and cellular level and their role during homeostasis and disease with a particular focus on the translational potential of this research. Our seminar will empower young bench scientists to showcase their work to peers and selected leaders in the field, who will provide concerted mentoring. It will foster exchange of ideas and experiences leading to new collaborations and further grassroots-driven integration in the field as well as career development.

Related Meeting

This GRS was held in conjunction with the "Chemotactic Cytokines" Gordon Research Conference (GRC). Refer to the associated GRC program page for more information.

Contributors

Final Meeting Program

Saturday
1:30 pm - 4:30 pmArrival and Check-in
3:00 pm - 3:15 pmIntroductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair
3:15 pm - 4:00 pmChemokines and Cell Migration
Discussion Leader: Amanda Proudfoot (Chemokine Biologist, Freelance Consultant, France)
3:15 pm - 3:30 pmIntroduction by Discussion Leader
3:30 pm - 3:40 pmNatasha Moussouras (Medical College of Wisconsin, USA)
"Structural Interactions and Implications of Post-Translationally Modified CCR7 and CCL21"
3:40 pm - 3:45 pmDiscussion
3:45 pm - 3:55 pmSarah Riutta (Medical College of Wisconsin, USA)
"Structure-Function Studies of the Highly Specific CCL20/CCR6 Signaling Axis"
3:55 pm - 4:00 pmDiscussion
4:00 pm - 5:30 pmPoster Session
5:30 pm - 7:30 pmChemokines and Cell Migration (continued) / Chemokine Control of Immune Activation
Discussion Leaders: Amanda Proudfoot (Chemokine Biologist, Freelance Consultant, France) and Reinhold Foerster (Hannover Medical School, Germany)
5:30 pm - 5:40 pmAnneleen Mortier (KU Leuven, Belgium)
"The Positively Charged CXCL9(74-103) Peptide Competes for GAG Binding with Inflammatory Chemokines and Inhibits Chemokine-Induced Neutrophil Extravasation and MSU Crystal-Induced Gout in Mice"
5:40 pm - 5:45 pmDiscussion
5:45 pm - 5:55 pmTamara Girbl (Queen Mary University of London, United Kingdom)
"Sequential Chemotactic Cues Guide Neutrophils Through Distinct Cellular Barriers of Blood Vessel Walls During Inflammation"
5:55 pm - 6:00 pmDiscussion
6:00 pm - 6:10 pmMohammad Jafarnejad (Imperial College London, United Kingdom)
"Computational Model of CCL19 and CCL21 Transport in the Lymph Node"
6:10 pm - 6:15 pmDiscussion
6:15 pm - 6:30 pmIntroduction by Discussion Leader
6:30 pm - 6:40 pmEgle Radice (Institute for Research in Biomedicine, Switzerland)
"Functional ACKR3 Expression in the B Cell Compartment"
6:40 pm - 6:45 pmDiscussion
6:45 pm - 6:55 pmCaroline Sokol (Massachusetts General Hospital, USA)
"CCR8 Directs the Initiation of Th2 Cell Differentiation"
6:55 pm - 7:00 pmDiscussion
7:00 pm - 7:10 pmShafqat Jaigirdar (University of Glasgow, United Kingdom)
"Sphingosine-1-Phosphate and Its Receptors Play a Key Role in the Retention of Activated CD4 T Cells at Inflamed Tissue Sites"
7:10 pm - 7:15 pmDiscussion
7:15 pm - 7:25 pmGillian Wilson (University of Glasgow, United Kingdom)
"Atypical Chemokine Receptor ACKR2 Controls Branching Morphogenesis in the Developing Mammary Gland"
7:25 pm - 7:30 pmDiscussion
8:00 pmDinner
Sunday
7:30 am - 8:30 amBreakfast
9:00 am - 11:00 amChemokines in Host Defense, Chronic Inflammation and Cancer
Discussion Leaders: Eleanor Fish (University of Toronto / University Health Network, Canada) and Gerry Graham (University of Glasgow, United Kingdom)
9:00 am - 9:20 amIntroduction by Discussion Leader
9:20 am - 9:30 amMonica Thomas (Medical College of Wisconsin, USA)
"Structural Investigations on the Pathologic Function of CCL28"
9:30 am - 9:35 amDiscussion
9:35 am - 9:45 amDaiane Boff (KU Leuven, Belgium)
"Role of Receptor CXCR2 in the Pathogenesis of Experimental Septic Arthritis"
9:45 am - 9:50 amDiscussion
9:50 am - 10:00 amHaneen Basheer (University of Bradford, United Kingdom)
"Role of CCR7 in Head and Neck Cancer"
10:00 am - 10:05 amDiscussion
10:05 am - 10:15 amChris Hansell (University of Glasgow, United Kingdom)
"The Atypical Chemokine Receptor, ACKR2, Constrains NK Cell Activity and Promotes Metastasis"
10:15 am - 10:20 amDiscussion
10:20 am - 10:30 amViola Puddinu (Institute for Research in Biomedicine, Switzerland)
"ACKR3 in B Cell Lymphoma"
10:30 am - 10:35 amDiscussion
10:35 am - 10:45 amRaimond Heukers (Vrije Universiteit Amsterdam, The Netherlands)
"Nanobody-Mediated Modulation of Oncogenic Properties of HCMV-Encoded Chemokine Receptor"
10:45 am - 10:50 amDiscussion
10:50 am - 11:00 amGeneral Discussion
11:00 am - 12:30 pmPoster Session

Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pmLunch
1:30 pm - 2:30 pmMentorship Component: Career Panel
Discussion Leader: Maud Deruaz (Massachusetts General Hospital, Harvard Medical School, USA)
1:30 pm - 1:50 pmIntroduction by Discussion Leader
1:50 pm - 2:25 pmPanel Discussion
"Tips and Tricks to Develop a Successful Career"
  • Joanna Groom (Walter and Eliza Hall Institute of Medical Research, Australia)
  • Clive McKimmie (University of Leeds, United Kingdom)
  • Amanda Proudfoot (Chemokine Biologist, Freelance Consultant, France)
  • Ann Richmond (Vanderbilt University, USA)
2:25 pm - 2:30 pmClosing Remarks
2:30 pm - 3:00 pmEvaluation Period
Fill in GRS Evaluation Forms
3:00 pmSeminar Concludes
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