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Lipoprotein Metabolism (GRS)
Gordon Research Seminar

Recent Advances in Lipoprotein Physiology and Related Disease

Dates

June 11-12, 2016

Location

Waterville Valley
Waterville Valley, NH

Organizers

Chairs:
Scott M. Gordon & Marjolein A. van den Boogert

Meeting Description

Gordon Research Seminars (GRS) are a unique forum for graduate students, post-docs, and other scientists with comparable levels of experience and education to present and exchange new data and cutting edge ideas.

At the 2016 Lipoprotein Metabolism GRS, young scientists will present their recent unpublished work in a friendly, low-intimidation environment. Presented topics will cover a broad range of interests related to lipoprotein physiology and cardiovascular disease. The meeting will also contain a mentoring component, led by an established investigator, with the goal of providing valuable career advice to attendees.

Related Meeting

This GRS was held in conjunction with the "Lipoprotein Metabolism" Gordon Research Conference (GRC). Refer to the associated GRC program page for more information.

Contributors

Final Meeting Program

Saturday
2:00 pm - 5:00 pmArrival and Check-in
3:30 pm - 3:45 pmIntroductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair
3:45 pm - 4:30 pmKeynote Session: Tribbles-1: A Novel Locus Regulating Lipid Metabolism Identified from Human Genetics
Discussion Leaders: John Melchior (University of Cincinnati, USA) and Eser Zerenturk (Baker IDI Heart and Diabetes Institute, Australia)
3:45 pm - 4:15 pmRobert Bauer (University of Pennsylvania, USA)
"Tribbles-1: A Novel Locus Regulating Lipid Metabolism Identified from Human Genetics"
4:15 pm - 4:30 pmDiscussion
4:30 pm - 6:00 pmPoster Session
6:00 pmDinner
7:30 pm - 9:30 pmLipoprotein Composition and Function
Discussion Leaders: Caitlin Murdoch (Duke University Medical Center, USA) and Allison Andraski (Harvard T.H. Chan School of Public Health, USA)
7:30 pm - 7:45 pmAllyson Morton (Harvard T.H. Chan School of Public Health, USA)
"ApoE and ApoC-III Interact to Modulate the Metabolism of HDL ApoA-I in Humans"
7:45 pm - 7:50 pmDiscussion
7:50 pm - 8:05 pmAmy Burke (University of Western Ontario, Canada)
"Naringenin Supplementation of a Low Fat Diet Enhances the Reversal of Metabolic Dysfunction, Promotes Atherosclerosis Regression and Improves Lesion Pathology in Ldlr-/- Mice"
8:05 pm - 8:10 pmDiscussion
8:10 pm - 8:25 pmRebecca Holme (Medical College of Wisconsin, USA)
"Modification of HDL by Reactive Aldehydes Impairs HDL's Athero-Protective Functions"
8:25 pm - 8:30 pmDiscussion
8:30 pm - 8:45 pmMonika Sharma (University of Otago, New Zealand)
"Calcium Dependent Endocytosis and Recycling of Lipoprotein(a) in HepG2 Cells"
8:45 pm - 8:50 pmDiscussion
8:50 pm - 9:05 pmJohn Melchior (University of Cincinnati, USA)
"Apolipoprotein A-II Impacts the Lipoproteome, Structure and Function of Apolipoprotein A-I Containing Lipoproteins"
9:05 pm - 9:10 pmDiscussion
9:10 pm - 9:25 pmJames Thierer (Carnegie Institution for Science / Johns Hopkins University, USA)
"The Larval Zebrafish as a Model for Beta-Lipoprotein Biology and Unbiased Drug Discovery"
9:25 pm - 9:30 pmDiscussion
Sunday
7:30 am - 8:30 amBreakfast
9:00 am - 11:00 amGenetic Regulation of Lipoprotein Metabolism and Atherosclerosis
Discussion Leaders: Lars Elmann Larsen (AMC Medical Research, The Netherlands) and Robert Bauer (University of Pennsylvania, USA)
9:00 am - 9:20 amXin Bi (University of Pennsylvania, USA)
"C6orf106 Is a Novel Regulator of Lipoprotein Metabolism"
9:20 am - 9:30 amDiscussion
9:30 am - 9:50 amCassandra Hayne (University of North Carolina at Chapel Hill, USA)
"Biochemical Analysis of the LPL Truncation Variant, LPLS447X"
9:50 am - 10:00 amDiscussion
10:00 am - 10:20 amLiye Zhou (SUNY Downstate Medical Center, USA)
"MiR-1200 Differentially Modulates Plasma LDL and HDL-Cholesterol Levels to Reduce Hyperlipidemia and Atherosclerosis in Mice"
10:20 am - 10:30 amDiscussion
10:30 am - 10:50 amEser Zerenturk (Baker IDI Heart and Diabetes Institute, Australia)
"Identification of Novel Regulators of Cholesterol Metabolism with Therapeutic Potential for Cardiovascular Disease"
10:50 am - 11:00 amDiscussion
11:00 am - 12:30 pmPoster Session

Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pmLunch
1:30 pm - 2:30 pmMentorship Component: Career Panel
Discussion Leaders: Scott Gordon (National Heart, Lung, and Blood Institute, NIH, USA) and Marjolein van den Boogert (Academic Medical Center, The Netherlands)
1:30 pm - 2:30 pmPanel Discussion
"A Successful Career in Academic Research"
  • Frank Sacks (Harvard T.H. Chan School of Public Health, USA)
  • Kasey Vickers (Vanderbilt University Medical Center, USA)
2:30 pm - 3:00 pmEvaluation Period
Fill in GRS Evaluation Forms
3:00 pmSeminar Concludes

Funding for this conference was made possible (in part) by 1R13HL132403-01 from the National Institutes of Health. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.
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