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Molecular Basis of Microbial One-Carbon Metabolism (GRS)
Gordon Research Seminar

From Enzyme Mechanisms to Multispecies Interactions: Understanding Biological One-Carbon Conversions to Address Future Challenges

Dates

July 30-31, 2016

Location

Waterville Valley
Waterville Valley, NH

Organizers

Chairs:
Dipti D. Nayak & Kai Schuchmann

Meeting Description

The Gordon Research Seminar on Molecular Basis of Microbial One-Carbon Metabolism is a unique forum for graduate students, post-docs, and other scientists with comparable levels of experience and education to present and exchange new data and cutting edge ideas.

Microbial metabolism of one-carbon compounds is pivotal to life: a key to its origins and a crucial player in the production and transformation of greenhouse gases. The focus of this meeting is on all microbially mediated processes that generate and consume carbon dioxide and methane as well as other ecologically relevant one-carbon compounds. Discussions of current challenges as well as emerging concepts and approaches in this interdisciplinary field will include research areas ranging from biochemistry, genetics, ecology and evolution, to geochemistry and synthetic biology.

Related Meeting

This GRS was held in conjunction with the "Molecular Basis of Microbial One-Carbon Metabolism" Gordon Research Conference (GRC). Refer to the associated GRC program page for more information.

Contributors

Final Meeting Program

Saturday
2:00 pm - 5:00 pmArrival and Check-in
3:30 pm - 3:45 pmIntroductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair
3:45 pm - 4:30 pmKeynote Session: C1 and H2 - Friends for a Lifetime
Discussion Leader: Frank Bengelsdorf (Ulm University, Germany)
3:45 pm - 4:00 pmOpening Remarks
4:00 pm - 4:25 pmBernhard Schink (University of Konstanz, Germany)
"C1 and H2 - Friends for a Lifetime"
4:25 pm - 4:30 pmDiscussion
4:30 pm - 6:00 pmPoster Session
6:00 pmDinner
7:30 pm - 9:30 pmEnzyme Mechanisms and Applications of C1 Metabolism
Discussion Leader: Lisa Stein (University of Alberta, Canada)
7:30 pm - 7:45 pmYoko Chiba (Japan Agency for Marine-Earth Science and Technology, Japan)
"Discovery of PPi-Type Phosphoenolpyruvate Carboxykinase and Its Physiological Importance"
7:45 pm - 7:50 pmDiscussion
7:50 pm - 8:05 pmDuncan Kountz (Ohio State University, USA)
"Demethylation of L-Carnitine by the Intestinal Acetogen Eubacterium limosum Avoids Production of Proatherosclerotic Metabolites"
8:05 pm - 8:10 pmDiscussion
8:10 pm - 8:25 pmBin Li (Boston University, USA)
"The Importance of Redox Relay in CO2 Reduction: Ferredoxin Dictates 2-Oxoacid:Ferredoxin Oxidoreductase Activity"
8:25 pm - 8:30 pmDiscussion
8:30 pm - 8:45 pmAndrea Ochsner (ETH Zurich, Switzerland)
"Genome-Wide Investigation of Methylotrophy"
8:45 pm - 8:50 pmDiscussion
8:50 pm - 9:05 pmTristan Wagner (Max Planck Institute for Terrestrial Microbiology, Germany)
"Crystal Structures of Formyl-Methanofuran Dehydrogenase and Heterodisulfide Reductase: Methanogen's Trick to Couple Methane Formation to CO2 Fixation"
9:05 pm - 9:10 pmDiscussion
9:10 pm - 9:25 pmBenjamin Woolston (Massachusetts Institute of Technology, USA)
"Heterologous Production of 3-Hydroxybutyric Acid in C. ljungdahlii"
9:25 pm - 9:30 pmDiscussion
Sunday
7:30 am - 8:30 amBreakfast
9:00 am - 11:00 amFrom Single Cells to Ecosystems: Ecology, Evolution, and Physiology of C1 Metabolism
Discussion Leader: J. Colin Murrell (University of East Anglia, United Kingdom)
9:00 am - 9:15 amRafael Laso-Perez (Max Planck Institute for Marine Microbiology, Germany)
"Novel Archaeal-Bacterial Consortia Use Methanogenesis-Type Enzymes for Butane Oxidation"
9:15 am - 9:20 amDiscussion
9:20 am - 9:35 amSabrina Bibi-Triki (Génétique Moléculaire Génomique Microbiologie (GMGM, UMR7156), University of Strasbourg, France)
"Regulation of the dcm Islet Involved in Bacterial Degradation of Dichloromethane, a Major Pollutant"
9:35 am - 9:40 amDiscussion
9:40 am - 9:55 amMikayla Borton (Ohio State University, USA)
"Microbial Methylamine Metabolisms Conserved in Geographically Distinct Hydraulically Fractured Shale Wells"
9:55 am - 10:00 amDiscussion
10:00 am - 10:15 amJuliana Leonard (University of South Florida, USA)
"The Carbon Fixation Pathways of the Sulfur-Oxidizing Chemolithoautotrophic Endosymbiont of Riftia pachyptila"
10:15 am - 10:20 amDiscussion
10:20 am - 10:45 amPaula Welander (Stanford University, USA)
"A Distinct Sterol Biosynthetic Pathway in Aerobic Methanotrophs"
10:45 am - 10:50 amDiscussion
10:50 am - 11:00 amGeneral Discussion
11:00 am - 12:30 pmPoster Session

Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pmLunch
1:30 pm - 2:30 pmMentorship Component: Scientific Careers Beyond the PhD and Postdoc
Discussion Leader: Helen Jones (School of Life Sciences, University of Warwick, United Kingdom)
1:30 pm - 2:30 pmPanel Discussion
"Scientific Careers Beyond the PhD and Postdoc"
  • Michael Koepke (LanzaTech, USA)
  • J. Colin Murrell (University of East Anglia, United Kingdom)
  • Lisa Stein (University of Alberta, Canada)
  • Nicholas Wigginton (Science, American Association for the Advancement of Science (AAAS), USA)
2:30 pm - 3:00 pmEvaluation Period
Fill in GRS Evaluation Forms
3:00 pmSeminar Concludes
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