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Myelin (GRS)
Gordon Research Seminar

Unravelling Myelin: New Insights into Generation and Regeneration

Dates

May 14-15, 2016

Location

Renaissance Tuscany Il Ciocco
Lucca (Barga), Italy

Organizers

Chairs:
Abbe H. Crawford & Ethan G. Hughes

Meeting Description

The Gordon Research Seminar on Myelin is a unique forum for graduate students, post-docs, and other scientists with comparable levels of experience and education to present and exchange new data and cutting edge ideas.

The focus of this meeting is to bring together young scientists to discuss and explore the cellular mechanisms underlying myelination and remyelination. The meeting will feature an exciting program of scientific talks and poster sessions focusing on recent advances in our understanding of developmental myelination, oligodendroglia dynamics and plasticity, and myelin regeneration.

Related Meeting

This GRS was held in conjunction with the "Myelin" Gordon Research Conference (GRC). Refer to the associated GRC program page for more information.

Contributors

Final Meeting Program

Saturday
1:30 pm - 4:30 pmArrival and Check-in
3:00 pm - 3:15 pmIntroductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair
3:15 pm - 4:00 pmKeynote Session: Remyelination Therapeutics
Discussion Leaders: Greg Duncan (University of British Columbia, Canada) and David Gonsalvez (University of Melbourne, Australia)
3:15 pm - 3:45 pmJonah Chan (University of California, San Francisco, USA)
"Do Remyelination Therapies Prevent Axonal Degeneration After Inflammatory Demyelination?"
3:45 pm - 4:00 pmDiscussion
4:00 pm - 5:30 pmPoster Session
5:30 pm - 7:30 pmNew Insights into Myelination and Myelin Dynamics
Discussion Leaders: Marc Ford (University College London, United Kingdom) and David Lyons (University of Edinburgh, United Kingdom)
5:30 pm - 5:50 pmLorena Arancibia-Carcamo (University College London, United Kingdom)
"The Size of the Node of Ranvier in Health and Disease"
5:50 pm - 6:00 pmDiscussion
6:00 pm - 6:20 pmSonia Mayoral (University of California, San Francisco, USA)
"A GPCR Screen Identifies a Novel Role for the Kappa-Opioid Receptor in Promoting Myelination"
6:20 pm - 6:30 pmDiscussion
6:30 pm - 6:50 pmAmy Herbert (Washington University in St. Louis, USA)
"A Forward Genetics Approach to Understand the Molecular Mechanisms of Myelination"
6:50 pm - 7:00 pmDiscussion
7:00 pm - 7:20 pmSueli Marques (Karolinska Institutet, Sweden)
"Oligodendrocyte Heterogeneity in the Mouse Central Nervous System"
7:20 pm - 7:30 pmDiscussion
8:00 pmDinner
Sunday
7:30 am - 8:30 amBreakfast
9:00 am - 11:00 amRegeneration and Repair of Myelin
Discussion Leaders: Andrew Caprariello (University of Calgary, Canada) and Alison Lloyd (MRC Laboratory for Molecular Cell Biology, University College London, United Kingdom)
9:00 am - 9:20 amValerie Brugger (University of Fribourg, Switzerland)
"Functions of Histone Deacetylases in Schwann Cells During Regeneration"
9:20 am - 9:30 amDiscussion
9:30 am - 9:50 amJessica Fletcher (University of Melbourne, Australia)
"TrkB Activation Promotes Myelin Repair in the Brain Following Cuprizone Demyelination"
9:50 am - 10:00 amDiscussion
10:00 am - 10:20 amJennifer Orthmann-Murphy (Johns Hopkins University School of Medicine, USA)
"In Vivo Imaging of Cortical Demyelination and Remyelination"
10:20 am - 10:30 amDiscussion
10:30 am - 10:50 amYvonne Dombrowski (Queen's University Belfast, United Kingdom)
"Regulatory T Cells Are Required for Oligodendrocyte Differentiation in Demyelinated CNS Lesions In Vivo"
10:50 am - 11:00 amDiscussion
11:00 am - 12:30 pmPoster Session

Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pmLunch
1:30 pm - 2:30 pmNovel Approaches to Myelin Therapeutics
Discussion Leaders: Stephen Fancy (University of California, San Francisco, USA) and Tracy Yuen (Genentech, Inc., USA)
1:30 pm - 1:50 pmStefanie Giera (Boston Children's Hospital / Harvard Medical School, USA)
"The Role of GPR56 and Its Ligand in Remyelination"
1:50 pm - 2:00 pmDiscussion
2:00 pm - 2:20 pmMeredith Hartley (Oregon Health and Science University, USA)
"Thyroid Hormone Mimetics as a Therapeutic Strategy for Demyelinating Diseases"
2:20 pm - 2:30 pmDiscussion
2:30 pm - 3:00 pmEvaluation Period
Fill in GRS Evaluation Forms
3:00 pmSeminar Concludes

Research reported in this publication was supported by the National Institute of Neurological Disorders and Stroke of the National Institutes of Health under Award Number R13NS096944. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.
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