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Chemistry and Biology of Peptides (GRS)
Gordon Research Seminar

Peptides and Peptidomimetics: Inspired by Nature and Applied by Scientists

Dates

February 20-21, 2016

Location

Ventura Beach Marriott
Ventura, CA

Organizers

Chairs:
Neha Garg & Astrid Knuhtsen

Meeting Description

The Gordon Research Seminar on Chemistry and Biology of Peptides is a unique forum for graduate students, post-docs, and other scientists with comparable levels of experience and education to present and exchange new data and cutting edge ideas.

This meeting will focus on advancements in the development of novel peptides guided by nature and synthetic chemistry, and in their application to biological systems and biomaterials. The seminar will include both oral and poster presentations which will be followed by discussion fostering constructive communication between young scientists participating in the seminar. A concluding session by a career panel with senior researchers from both industry and academia will provide a platform to help young scientists gain broader knowledge and insights into opportunities and challenges associated with various career options in the peptide field.

Related Meeting

This GRS was held in conjunction with the "Chemistry and Biology of Peptides" Gordon Research Conference (GRC). Refer to the associated GRC program page for more information.

Contributors

Final Meeting Program

Saturday
2:00 pm - 5:00 pmArrival and Check-in
3:30 pm - 3:45 pmIntroductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair
3:45 pm - 4:30 pmPeptides in Infectious Diseases
Discussion Leaders: Tracy Stone (Hospital for Sick Children, Canada) and Anna Maria Papini (University of Florence, Italy / University of Cergy-Pontoise, France)
3:45 pm - 4:00 pmNir Qvit (Stanford University, USA)
"A Rational Design of Novel Inhibitors Inhibiting Kinetoplastid Infectious Disease"
4:00 pm - 4:05 pmDiscussion
4:05 pm - 4:25 pmDon Nguyen (University of California, San Diego, USA)
"The Peptidic Toolbox of Pseudomonas"
4:25 pm - 4:30 pmDiscussion
4:30 pm - 6:00 pmPoster Session
6:00 pmDinner
7:30 pm - 9:30 pmStructure Activity Relationships of Peptide Therapeutics
Discussion Leaders: Arundhati Nag (California Institute of Technology, USA) and Gozde Ulas (University of California, San Francisco, USA)
7:30 pm - 7:45 pmMarlies Hager (University of Wisconsin-Madison, USA)
"Backbone Modification of Glucagon-Like Peptide 1 Induces Conformational Selectivity at the GLP-1 Receptor"
7:45 pm - 7:50 pmDiscussion
7:50 pm - 8:05 pmAswini Giri (University of Arizona, USA)
"Peptide Based Multifunctional Molecules with Agonist Activities at MOR/DOR and Antagonist Activity at NK1R for the Treatment of Pain"
8:05 pm - 8:10 pmDiscussion
8:10 pm - 8:25 pmJean-Daniel Malcor (University of Cambridge, United Kingdom)
"The Synthesis and Coupling of Photoreactive Collagen-Based Peptides to Restore Integrin Reactivity to Chemically-Crosslinked Collagen"
8:25 pm - 8:30 pmDiscussion
8:30 pm - 8:45 pmDaniel Baxter (University of Bath, United Kingdom)
"Cell-Permeable Helix-Constrained Peptides Inhibit Activator Protein-1 and Reduce Cancer Cell Viability"
8:45 pm - 8:50 pmDiscussion
8:50 pm - 9:05 pmSoohyun Kwon (Institute for Molecular Bioscience, University of Queensland, Australia)
"Application of Sortase A in Disulfide-Rich Peptide Engineering"
9:05 pm - 9:10 pmDiscussion
9:10 pm - 9:25 pmIvan Zemskov (Universitat Konstanz, Germany)
"Total Synthesis of Microcystins and Unnatural Derivatives Thereof"
9:25 pm - 9:30 pmDiscussion
Sunday
7:30 am - 8:30 amBreakfast
9:00 am - 11:00 amApplying Peptides for the Greater Good
Discussion Leaders: Mingxun Wang (University of California, San Diego, USA) and Jessica Wynn (Virginia Polytechnic Institute and State University, USA)
9:00 am - 9:15 amMark Walker (University of Illinois at Urbana-Champaign, USA)
"Yeast Surface Display of Ribosomally Synthesized and Post-Translationally Modified Peptides"
9:15 am - 9:20 amDiscussion
9:20 am - 9:35 amSarah Apple (University of Utah, USA)
"Design of a Trimeric D-Peptide Ebolavirus Entry Inhibitor"
9:35 am - 9:40 amDiscussion
9:40 am - 9:55 amChristina Schroeder (Institute for Molecular Bioscience, Australia)
"Rational Design and Synthesis of a Novel Membrane Binding NaV1.8 Selective Inhibitor with In Vivo Activity in Pain Models"
9:55 am - 10:00 amDiscussion
10:00 am - 10:15 amSvetlana Ikonomova (University of Maryland, USA)
"Effect of Lysine Substitution on Degradation of Histatin-5 by Candida albicans Secreted Aspartic Proteases"
10:15 am - 10:20 amDiscussion
10:20 am - 10:35 amTyson Moyer (Massachusetts Institute of Technology, USA)
"Tuning Multimeric Architecture of Peptide Antigens on Nanoparticles in Vaccine Design"
10:35 am - 10:40 amDiscussion
10:40 am - 10:55 amRosemary Adaba (University of Aberdeen, United Kingdom)
"Isolation and Standard Free Quantification of Cyclic Peptides"
10:55 am - 11:00 amDiscussion
11:00 am - 12:30 pmPoster Session

Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pmLunch
1:30 pm - 2:30 pmMentorship Component: Career Panel
Discussion Leaders: Cody Lensing (University of Minnesota, USA) and Astrid Knuhtsen (University of Copenhagen, Denmark)
1:30 pm - 2:30 pmPanel Discussion
"Career Paths: Navigating the Journey"
  • Thomas Kodadek (The Scripps Research Institute, Scripps Florida, USA)
  • William Pomerantz (University of Minnesota, USA)
  • Natia Tsomaia (Ipsen, USA)
2:30 pm - 3:00 pmEvaluation Period
Fill in GRS Evaluation Forms
3:00 pmSeminar Concludes
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