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Cell Contact & Adhesion (GRS)
Gordon Research Seminar

How Cells Stick, Slide, and Impact Our Lives

Dates

June 17-18, 2017

Location

Proctor Academy
Andover, NH Site Information

Organizers

Chair:
Torey Arnold

Application Deadline

Applications for this meeting must be submitted by May 20, 2017. Please apply early, as some meetings become oversubscribed (full) before this deadline. If the meeting is oversubscribed, it will be stated here. Note: Applications for oversubscribed meetings will only be considered by the Conference Chair if more seats become available due to cancellations.

GRS Speaker Abstract Deadline: Although applications will be accepted until the date noted above, any applicants who wish to be considered for an oral presentation should submit their application by March 17, 2017. Please refer to the application instructions in the Meeting Description section below for more details (if available).

Meeting Description

Overview

The Gordon Research Seminar on Cell Contact and Adhesion is a forum for graduate students and postdocs to share and discuss cutting edge research in a constructive environment. The focus of this meeting will be to understand cell-cell and cell-surface interaction from the scale of amino acids to whole tissues and will cover disciplines ranging from biophysics to developmental biology.

Application Instructions

The meeting will feature approximately 10 talks and 2 poster sessions. All attendees are expected to actively participate in the GRS either by giving an oral presentation or presenting a poster. Therefore, all applications must include an abstract.

The Chairs will select speakers from abstracts submitted by March 17, 2017. Those applicants who are not chosen for talks and those who apply after the deadline to be considered for an oral presentation will be expected to present a poster. In order to participate, you must submit an application by the date indicated in the Application Deadline section above.

Related Meeting

This GRS will be held in conjunction with the "Cell Contact & Adhesion" Gordon Research Conference (GRC). Those interested in attending both meetings must submit an application for the GRC in addition to an application for the GRS. Refer to the associated GRC program page for more information.

Contributors

Meeting Program

Saturday
2:00 pm - 5:00 pmArrival and Check-in
3:30 pm - 3:45 pmIntroductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair
3:45 pm - 4:30 pmAdhesion and Disease
Discussion Leader: Matthew Kutys (Boston University, USA)
3:45 pm - 3:50 pmOpening Remarks
3:50 pm - 4:05 pmAmber Caldara (Emory University, USA)
"A Novel Desmoglein 1 Mutation Abrogates Lipid Raft Targeting and Causes SAM Syndrome"
4:05 pm - 4:10 pmDiscussion
4:10 pm - 4:25 pmAdrian Luna (University of New Mexico Health Science Center, USA)
"The Interplay Between HPV Oncogene Expression and Contact Inhibition"
4:25 pm - 4:30 pmDiscussion
4:30 pm - 6:00 pmPoster Session
6:00 pmDinner
7:30 pm - 9:30 pmAdhesion Mechanics
Discussion Leaders: Junior West (University of Toronto, Canada) and Henri Huppert (Institute of Medical Biology, A*STAR, Singapore / University of Manchester, United Kingdom)
7:30 pm - 7:45 pmSamantha Barrick (University of Illinois at Urbana-Champaign, USA)
"Salt Bridges Gate Alpha-Catenin Activation at Intercellular Junctions"
7:45 pm - 7:50 pmDiscussion
7:50 pm - 8:05 pmAnant Chopra (Boston University, USA)
"Force Generation via β-Muscle Myosin, Titin, and α-Actinin Drives Cardiac Sarcomere Assembly from Focal Adhesions"
8:05 pm - 8:10 pmDiscussion
8:10 pm - 8:25 pmAnna-Lena Cost (Max Planck Institute of Biochemistry, Germany)
"Developing a Desmoplakin Tension Sensor"
8:25 pm - 8:30 pmDiscussion
8:30 pm - 8:45 pmKathryn Rosowski (ETH Zurich, Switzerland)
"Stiffening and Reinforcement of Adherent Fibroblasts During Stretch and Its Vinculin Dependence"
8:45 pm - 8:50 pmDiscussion
8:50 pm - 9:05 pmZainab Rahil (University of Illiniois at Urbana-Champaign, USA)
"Mechanoselectivity: Cell's Guide to Force Transduction"
9:05 pm - 9:10 pmDiscussion
9:10 pm - 9:25 pmCornelia Schwayer (IST Austria, Austria)
"Mechanochemical Feedback Loop Driving Epithelial Tissue Spreading in Zebrafish"
9:25 pm - 9:30 pmDiscussion
Sunday
7:30 am - 8:30 amBreakfast
9:00 am - 11:00 amMolecules to Organisms
Discussion Leaders: Anant Chopra (Boston University, USA) and Anna-Lena Cost (Max Planck Institute of Biochemistry, Germany)
9:00 am - 9:15 amShafali Gupta (Institute of Molecular Biosciences, University of Queensland, Australia)
"Active Response of E-Cadherin Junctions During Collective Cell Migration"
9:15 am - 9:20 amDiscussion
9:20 am - 9:35 amJunior West (University of Toronto, Canada)
"An Actomyosin-Arf-GEF Negative Feedback Loop for Tissue Elongation Under Stress"
9:35 am - 9:40 amDiscussion
9:40 am - 9:55 amPrateek Arora (Tata Institute of Fundamental Research, Mumbai, India)
"Reciprocal Interactions Between aPKC and Lgl with E-Cadherin Establish a Mechanically Robust Bi-Layered Epidermis During Zebrafish Development"
9:55 am - 10:00 amDiscussion
10:00 am - 10:15 amTeresa Bonello (University of North Carolina at Chapel Hill, USA)
"Defining the Network of Proteins Driving Apical-Basal Polarity Establishment in Early Drosophila Development"
10:15 am - 10:20 amDiscussion
10:20 am - 10:35 amTony Tsai (Harvard Medical School, USA)
"Cracking the Adhesion Code Underlying Robust Pattern Formation in Zebrafish Spinal Cord"
10:35 am - 10:40 amDiscussion
10:40 am - 10:55 amSarah Imtiaz (Max Planck Institute of Molecular Physiology, Germany)
"Studying the Formation and Function of Adhesion Sites by the Quantitative Multi-Parametric Analysis"
10:55 am - 11:00 amDiscussion
11:00 am - 12:30 pmPoster Session

Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pmLunch
1:30 pm - 2:30 pmRemodeling Adhesion
Discussion Leader: Torey Arnold (University of Michigan, USA)
1:30 pm - 1:45 pmSaranyaraajan Varadarajan (University of Michigan, USA)
"The Role of Calcium Influx in Remodeling of Epithelial Cell-Cell Junctions"
1:45 pm - 1:50 pmDiscussion
1:50 pm - 2:05 pmHenri Huppert (Institute of Medical Biology, A*STAR, Singapore / University of Manchester, United Kingdom)
"Regulation of Desmosome Internalisation"
2:05 pm - 2:10 pmDiscussion
2:10 pm - 2:25 pmMatthew Kutys (Boston University, USA)
"A Mechanosensitive Notch Complex Regulates Vascular Endothelial Junctions and Barrier Function"
2:25 pm - 2:30 pmDiscussion
2:30 pm - 3:00 pmEvaluation Period
Fill in GRS Evaluation Forms
3:00 pmSeminar Concludes

Funding for this conference was made possible (in part) by 1R13CA216892-01 from the National Cancer Institute and the Eunice Kennedy Shriver National Institute of Child Health and Human Development . The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention by trade names, commercial practices, or organizations imply endorsement by the U.S. Government.
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