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Fertilization and Activation of Development (GRS)
Gordon Research Seminar

Innovative Technologies and Groundbreaking Research in Fertilization Biology

Dates

July 15-16, 2017

Location

Holderness School
Holderness, NH

Organizers

Chairs:
Maria Gracia Gervasi & Miranda L. Bernhardt

Meeting Description

The Gordon Research Seminar (GRS) on Fertilization and Activation of Development offers a unique opportunity for junior researchers, such as graduate students, post-docs and early-career researchers, to share their original work through platform talks and poster presentations. This Gordon Research Seminar promotes valuable peer-to-peer interactions, and discussion of the latest advances in the field. It will also include a small number of scientific presentations from respected established investigators, who will also be available for scientific and mentoring discussions with participants. Participants are strongly encouraged to attend both the GRS and its associated Gordon Research Conference (GRC). The GRS gives its attendees the opportunity to engage and make connections within a smaller group of scientists prior to attending the full GRC meeting.

The GRS will focus on the innovative technologies and cutting-edge research applied to the study of gamete maturation, fertilization and early development. Topics to be discussed include epigenetics, metabolism, and gamete interactions, and special attention will be devoted to application of newly developed technologies to gametogenesis and fertilization research and ethical issues surrounding assisted reproductive technologies.

Related Meeting

This GRS was held in conjunction with the "Fertilization and Activation of Development" Gordon Research Conference (GRC). Refer to the associated GRC program page for more information.

Contributors

Meeting Program

Saturday
2:00 pm - 5:00 pmArrival and Check-in
3:30 pm - 3:45 pmIntroductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair
3:45 pm - 4:30 pmKeynote Session: Uniting the Genome: A Novel Role of piRNAs in the Germline
Discussion Leaders: Mark Kelly (University of Dundee, United Kingdom) and Lis del Carmen Puga Molina (Instituto de Biologia y Medicina Experimental, Argentina)
3:45 pm - 4:15 pmHaifan Lin (Stem Cell Center, Yale University, USA)
"Uniting the Genome: A Novel Role of piRNAs in the Germline"
4:15 pm - 4:30 pmDiscussion
4:30 pm - 6:00 pmPoster Session
6:00 pmDinner
7:30 pm - 9:30 pmNew Approaches to Germ Cell Biology
Discussion Leaders: Nicolas Brukman (Instituto de Biologia y Medicina Experimental, Argentina) and Amber Krauchunas (Rutgers University, USA)
7:30 pm - 7:50 pmTsutomu Endo (Whitehead Institute for Biomedical Research, USA)
"Oscillation of Retinoic Acid Coordinates Spermatogenesis to Ensure Continuous Sperm Production"
7:50 pm - 8:00 pmDiscussion
8:00 pm - 8:20 pmAmanda Bayer (Northwestern University, USA)
"Zinc-Mediated Nuclear Restructuring Protects Against DNA Damage During Sperm Capacitation"
8:20 pm - 8:30 pmDiscussion
8:30 pm - 8:50 pmGiulia Vigone (UConn Health, USA)
"Synergistic Activities of Multiple Cyclic AMP Phosphodiesterases Prevent Premature Meiotic Progression, Ovulation and Progesterone Signaling in Mouse Ovarian Follicles"
8:50 pm - 9:00 pmDiscussion
9:00 pm - 9:20 pmWei Cui (University of Massachusetts Amherst, USA)
"Using CRISPR/Cas to Generate Animal Models and Explore Gene Function During Embryogenesis"
9:20 pm - 9:30 pmDiscussion
Sunday
7:30 am - 8:30 amBreakfast
9:00 am - 11:00 amEpigenetics, Metabolism, and New Advances in Fertilization Research
Discussion Leaders: Naseer Kutchy (Mississippi State University, USA) and Carla Ritagliati (IBR-CONICET, Argentina)
9:00 am - 9:20 amUpasna Sharma (University of Massachusetts Medical School, USA)
"Biogenesis and Function of Small RNAs During Sperm Maturation and Fertilization"
9:20 am - 9:30 amDiscussion
9:30 am - 9:50 amEdgar Vogt (National Institutes of Health, USA)
"Loss of Mater, a Maternal-Effect Gene, Delays Cortical Granule Exocytosis in Mouse Eggs"
9:50 am - 10:00 amDiscussion
10:00 am - 10:20 amJulia Floehr (University Hospital RWTH Aachen, Germany)
"Down-Regulation of the Liver-Derived Plasma Protein Fetuin-B Mediates Reversible Female Infertiliy"
10:20 am - 10:30 amDiscussion
10:30 am - 10:50 amBen Hopkins (University of Oxford, United Kingdom)
"Drosophila Accessory Gland Secondary Cells Mediate Between-Male Competition for Fertilizations"
10:50 am - 11:00 amDiscussion
11:00 am - 12:30 pmPoster Session

Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pmLunch
1:30 pm - 2:30 pmMentorship Component: The Other Side of the Dish
Discussion Leaders: Goli Ardestani (University of Massachusetts Amherst, USA) and Emir Aviles Pagan (Whitehead Institute for Biomedical Research, MIT, USA)
1:30 pm - 2:30 pmPanel Discussion
"Ethics and Safety Considerations for Assisted Reproduction"
  • Marisa Bartolomei (University of Pennsylvania, USA)
  • Paolo Rinaudo (University of California, San Francisco, USA)
2:30 pm - 3:00 pmEvaluation Period
Fill in GRS Evaluation Forms
3:00 pmSeminar Concludes

Research reported in this publication was supported by the Eunice Kennedy Shriver National Institute Of Child Health & Human Development of the National Institutes of Health under Award Number U13HD091983. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.
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