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Lung Development, Injury and Repair (GRS)
Gordon Research Seminar

Resolving Lung Injury - From Causes to Mechanisms to Treatments

Dates

August 19-20, 2017

Location

Colby-Sawyer College
New London, NH

Organizers

Chairs:
Alexandra Noel & Poornima Mahavadi

Meeting Description

The Gordon Research Seminar on Lung Development, Injury and Repair is a unique forum for graduate students, post-docs, and other scientists with comparable levels of experience and education to present and exchange new data and cutting edge ideas.

This 2017 meeting will focus on new frontiers in pulmonary health and disease, highlighting in vitro, in vivo and clinical studies linking causes and mechanisms which are paving ways for new therapies and treatments. The GRS will also include a mentorship component on the various career opportunities in this research field.

Related Meeting

This GRS was held in conjunction with the "Lung Development, Injury and Repair" Gordon Research Conference (GRC). Refer to the associated GRC program page for more information.

Contributors

Meeting Program

Saturday
2:00 pm - 5:00 pmArrival and Check-in
3:30 pm - 3:45 pmIntroductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair
3:45 pm - 4:30 pmKeynote Session: New Frontiers in Pulmonary Health and Disease
Discussion Leader: Susan Guttentag (Vanderbilt University, USA)
3:45 pm - 3:55 pmIntroduction by Discussion Leader
3:55 pm - 4:20 pmGisli Jenkins (University of Nottingham, United Kingdom)
"Can Breathing Promote Lung Fibrosis? The Role of Mechanotransduction and Integrins in the Development of Pulmonary Fibrosis"
4:20 pm - 4:25 pmDiscussion
4:25 pm - 4:30 pmGeneral Discussion
4:30 pm - 6:00 pmPoster Session
6:00 pmDinner
7:30 pm - 9:30 pmLinking Lung Development, Injury and Repair: Lessons from In Vitro and In Vivo Studies
Discussion Leader: Andreas Guenther (Justus Liebig University Giessen, Germany)
7:30 pm - 7:35 pmIntroduction by Discussion Leader
7:35 pm - 7:50 pmLeonor Gouveia (Uppsala University, Sweden)
"Lung-Specific Deletion of Pdgfa Leads to Alveolar Development Arrest"
7:50 pm - 7:55 pmDiscussion
7:55 pm - 8:10 pmVeronika Winkelmann (University of Ulm, Germany)
"Barrier Disturbances of the Alveolar-Capillary Barrier"
8:10 pm - 8:15 pmDiscussion
8:15 pm - 8:30 pmYue Ren (University of Rochester Medical Center, USA)
"Regulation of Connective Tissue Type Mast Cells and Their Role in Bronchopulmonary Dysplasia"
8:30 pm - 8:35 pmDiscussion
8:35 pm - 8:50 pmYan (Tina) Zhang (University of California, San Diego, USA)
"E3 Ubiquitin Ligase FBXW7 Controls Airway Cell Fate"
8:50 pm - 8:55 pmDiscussion
8:55 pm - 9:10 pmNathalie Fuentes (Penn State College of Medicine, USA)
"Estrogen Regulation of Inflammatory Mediators and Pulmonary Function in Ozone-Induced Inflammation"
9:10 pm - 9:15 pmDiscussion
9:15 pm - 9:30 pmGeneral Discussion
Sunday
7:30 am - 8:30 amBreakfast
9:00 am - 11:00 amInsights from Basic Research Paving the Way for New Therapies
Discussion Leader: Kent Pinkerton (University of California, Davis, USA)
9:00 am - 9:20 amStephania Cormier (University of Tennessee Health Science Center, USA)
"Exposure of the Developing Lung to Environmental Pollutants and the Development of Asthma"
9:20 am - 9:25 amDiscussion
9:25 am - 9:40 amSander van Riet (Leiden University Medical Center, The Netherlands)
"Generation of Alveolar Epithelial Cells and Endothelial Cells from Human Induced Pluripotent Stem Cells"
9:40 am - 9:45 amDiscussion
9:45 am - 10:00 amJared Mereness (University of Rochester, USA)
"Type IV Collagen Promotes Pulmonary Epithelial Spreading and Wound-Closure via Integrin 1 and PI3K"
10:00 am - 10:05 amDiscussion
10:05 am - 10:20 amJennifer Sucre (Vanderbilt University, USA)
"Hyperoxia Exposure of Developing Lung Epithelium Promotes Activated Wnt Signaling in Underlying Mesenchyme"
10:20 am - 10:25 amDiscussion
10:25 am - 10:40 amPrajakta Oak (Comprehensive Pneumology Center, Helmholtz Zentrum Muenchen, Germany)
"Monocyte-Centered Inflammatory Responses Driving Pulmonary Injury in Neonatal Chronic Lung Disease"
10:40 am - 10:45 amDiscussion
10:45 am - 10:55 amAnkita Burman (Vanderbilt University, USA)
"ER Stress Effector C/EBP Homologous Protein (CHOP) Augments AEC Apoptosis and Worsens Lung Fibrosis"
10:55 am - 11:00 amDiscussion
11:00 am - 12:30 pmPoster Session

Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pmLunch
1:30 pm - 2:30 pmMentorship Component: Careers Opportunities with a PhD: Academia, Government and Industry
Discussion Leader: Jason Rock (Boston University School of Medicine, USA)
1:30 pm - 1:40 pmIntroduction by Discussion Leader: An Academic Perspective
1:40 pm - 2:30 pmPanel Discussion
"Careers Opportunities with a Ph.D. - Point of Views of the Industry (Pharma) and the Government (NHLBI)"
  • James Kiley (National Heart, Lung and Blood Institute, NIH, USA)
  • Paul Levesque (Bristol-Myers Squibb, USA)
2:30 pm - 3:00 pmEvaluation Period
Fill in GRS Evaluation Forms
3:00 pmSeminar Concludes
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