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Malaria (GRS)
Gordon Research Seminar

The Basic Science of Malaria: A Springboard for New Approaches to Control and Elimination

Dates

July 1-2, 2017

Location

Les Diablerets Conference Center
Les Diablerets, Switzerland Site Information

Organizers

Chairs:
Vanessa Zuzarte-Luis & Kristina S. Burrack

Application Deadline

Applications for this meeting must be submitted by June 3, 2017. Please apply early, as some meetings become oversubscribed (full) before this deadline. If the meeting is oversubscribed, it will be stated here. Note: Applications for oversubscribed meetings will only be considered by the Conference Chair if more seats become available due to cancellations.

GRS Speaker Abstract Deadline: Although applications will be accepted until the date noted above, any applicants who wish to be considered for an oral presentation should submit their application by April 1, 2017. Please refer to the application instructions in the Meeting Description section below for more details (if available).

Meeting Description

Overview

The Gordon Research Seminar on Malaria is a unique forum for graduate students, post-docs, and other scientists with comparable levels of experience and education to present and exchange new data and cutting edge ideas.

New tools and strategies are needed to accelerate progress toward malaria control and elimination. To successfully meet this challenge we need a clearer understanding of the complex interplay between the Plasmodium parasite, its mosquito vector and the vertebrate host it infects. The 2017 Malaria GRS will focus on the biology of Plasmodium infection at every stage of the parasite's life cycle. Organised in line with the Malaria GRC, that will host world leaders in the field of malaria, but also non-malaria scientists, this GRS will provide a unique informal forum for graduate students and postdocs to present and discuss their data side-by-side with senior scientists that are at the forefront of their research fields.

Application Instructions

The meeting will feature approximately 10 talks and 2 poster sessions. All attendees are expected to actively participate in the GRS either by giving an oral presentation or presenting a poster. Therefore, all applications must include an abstract.

The Chairs will select speakers from abstracts submitted by April 1, 2017. Those applicants who are not chosen for talks and those who apply after the deadline to be considered for an oral presentation will be expected to present a poster. In order to participate, you must submit an application by the date indicated in the Application Deadline section above.

Related Meeting

This GRS will be held in conjunction with the "Malaria" Gordon Research Conference (GRC). Those interested in attending both meetings must submit an application for the GRC in addition to an application for the GRS. Refer to the associated GRC program page for more information.

Meeting Program

Saturday
1:30 pm - 4:30 pmArrival and Check-in
3:00 pm - 3:15 pmIntroductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair
3:15 pm - 4:00 pmTechnology and Drug Development
Discussion Leader: Debakshi Mullick (Weizmann Institute of Science, Israel)
3:15 pm - 3:25 pmKolapo Oyebola (Medical Research Council Unit, The Gambia, Gambia)
"Pooled-DNA Sequencing Identifies Genomic Regions of Selection in Nigerian Isolates of Plasmodium falciparum"
3:25 pm - 3:30 pmDiscussion
3:30 pm - 3:40 pmMaria Penzo (London School of Hygiene and Tropical Medicine, United Kingdom)
"High-Throughput Screening to Develop New Inhibitors Against the Plasmodium falciparum Cyclic GMP-Dependent Protein Kinase"
3:40 pm - 3:45 pmDiscussion
3:45 pm - 3:55 pmAna Sanchez-Azqueta (University of Glasgow, United Kingdom)
"Targeting Protein Kinases in Malaria - The Potential of Inhibition of PfCLK3"
3:55 pm - 4:00 pmDiscussion
4:00 pm - 5:30 pmPoster Session
5:30 pm - 7:30 pmHost-Parasite Interactions
Discussion Leader: Pauline Orondo (Jomo Kenyatta University of Agriculture and Technology, Kenya)
5:30 pm - 5:40 pmDora Posfai (Duke University, USA)
"Aquaporin-3 an Essential Host Protein for the Development of Liver Stage Malaria"
5:40 pm - 5:50 pmDiscussion
5:50 pm - 6:00 pmKatharine Collins (QIMR Berghofer Medical Research Institute, Australia)
"Human to Mosquito Transmission of Plasmodium falciparum and Plasmodium vivax During Controlled Human Malaria Infection"
6:00 pm - 6:10 pmDiscussion
6:10 pm - 6:20 pmE. Nicole Arroyo (University of Washington, USA)
"The CD4+ T Cell Response to Murine Malaria Is Dominated by a Long-Lasting Tfh Phenotype"
6:20 pm - 6:30 pmDiscussion
6:30 pm - 6:40 pmKatherine Cumnock (Stanford University, USA)
"Metabolically Identified Interventions Alter Malaria Severity and Outcome"
6:40 pm - 6:50 pmDiscussion
6:50 pm - 7:00 pmRahul Chaudhari (Tata Institute of Fundamental Research, India)
"Glutathione and Thioredoxin Systems of Malaria Parasite Plasmodium falciparum: Partners in Crime?"
7:00 pm - 7:10 pmDiscussion
7:10 pm - 7:20 pmAwa Gneme (Université Ouaga 1 Professeur Joseph Ki-Zerbo, Burkina Faso)
"Seasonal Trends of P. falciparum Asexual Forms and Gametocytes and Susceptibility of Anopheles gambiae to Infection in Rural Burkina Faso"
7:20 pm - 7:30 pmDiscussion
8:00 pmDinner
Sunday
7:30 am - 8:30 amBreakfast
9:00 am - 11:00 amParasite Biology
Discussion Leader: Wiebke Nahrendorf (University of Edinburgh, United Kingdom)
9:00 am - 9:10 amAnna Barcons-Simon (Institut Pasteur, France)
"The Trans-Acting GC-Rich Non-Coding RNA Regulates Monoallelic var Gene Expression in Plasmodium falciparum"
9:10 am - 9:20 amDiscussion
9:20 am - 9:30 amNanika Coetzee (University of Pretoria, South Africa)
"Exploiting the Epigenomic and Proteomic Complexity of Plasmodium falciparum Gametocytogenesis"
9:30 am - 9:35 amDiscussion
9:35 am - 9:45 amGourab Paul (International Centre for Genetic Engineering and Biotechnology (ICGEB), India)
"Characterization of a Novel 6-Cys Protein Complex on the Surface of Plasmodium falciparum Blood-Stage Merozoites"
9:45 am - 9:55 amDiscussion
9:55 am - 10:05 amEkta Saini (International Centre for Genetic Engineering and Biotechnology (ICGEB), India)
"Photosensitized INA-Labelled Protein 1 (PhIL1) Is a Movel Component of the Inner Membrane Complex of All Invasive and Motile Stages of Plasmodium"
10:05 am - 10:10 amDiscussion
10:10 am - 10:20 amVandana Thakur (International Centre for Genetic Engineering and Biotechnology (ICGEB), India)
"Eps15 Homology Domain Containing Protein of P. falciparum (PfEHD) Associates with Endocytosis and Vesicular Trafficking Towards Neutral Lipid Storage Site"
10:20 am - 10:25 amDiscussion
10:25 am - 10:35 amMarta Walczak (Stanford University, USA)
"Atg8, How Plasmodium Borrows Autophagy Machinery for Apicoplast Biogenesis"
10:35 am - 10:40 amDiscussion
10:40 am - 10:50 amHao Yang (Australian National University, Australia)
"Role of Human Hydroxymethylbilane Synthase (hHMBS) in the Plasmodium falciparum"
10:50 am - 11:00 amDiscussion
11:00 am - 12:30 pmPoster Session

Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pmLunch
1:30 pm - 2:30 pmMalaria Pathogenesis
Discussion Leader: Sarah Boudova (University of Maryland School of Medicine, USA)
1:30 pm - 1:40 pmTemittope Ademolue (West African Centre for Cell Biology of Infectious Pathogens, Ghana)
"Patterns of Inflammatory Responses and Parasite Tolerance Vary with Malaria Transmission Intensity"
1:40 pm - 1:45 pmDiscussion
1:45 pm - 1:55 pmWhitney Harrington (University of Washington / Seattle Children's Hospital, USA)
"Cord Blood Maternal Microchimerism Is Associated with Protection from both Malaria- and Non-Malaria-Associated Pathology During Early Childhood"
1:55 pm - 2:00 pmDiscussion
2:00 pm - 2:10 pmPamela Odorizzi (University of California, San Francisco, USA)
"Investigating the Impact of In Utero Malaria Exposure on CD4+ T Cell Immunity in Infants"
2:10 pm - 2:15 pmDiscussion
2:15 pm - 2:25 pmOlivia Swann (Centre for Immunity, Infection and Evolution, United Kingdom)
"Neighbouring Polymorphisms in Complement Receptor 1 (CR1) Have Opposing Associations with Cerebral Malaria in Two Discrete African Case-Control Studies"
2:25 pm - 2:30 pmDiscussion
2:30 pm - 3:00 pmEvaluation Period
Fill in GRS Evaluation Forms
3:00 pmSeminar Concludes
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