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Staphylococcal Diseases (GRS)
Gordon Research Seminar

Staphylococci at the Host-Pathogen Interface

Dates

August 5-6, 2017

Location

Waterville Valley
Waterville Valley, NH Site Information

Organizers

Chairs:
Casey M. Gries & William Beavers

Application Deadline

Applications for this meeting must be submitted by July 8, 2017. Please apply early, as some meetings become oversubscribed (full) before this deadline. If the meeting is oversubscribed, it will be stated here. Note: Applications for oversubscribed meetings will only be considered by the Conference Chair if more seats become available due to cancellations.

GRS Speaker Abstract Deadline: Although applications will be accepted until the date noted above, any applicants who wish to be considered for an oral presentation should submit their application by May 5, 2017. Please refer to the application instructions in the Meeting Description section below for more details (if available).

Meeting Description

Overview

The Gordon Research Seminar on Staphylococcal Diseases is a unique forum for graduate students, post-docs, and other scientists with comparable levels of experience and education to present and exchange new data and cutting edge ideas.

This meeting will explore Staphylococci at the host-pathogen interface looking at both the bacterial and host responses during infection. Topics that will be presented include toxin generation, metabolic and signaling changes, and new models to study disease in vivo. The two-day seminar will include cutting-edge research presentations from trainees in the field as well as a mentorship panel featuring prominent scientists from academia, industry, and clinical settings.

Application Instructions

The meeting will feature approximately 10 talks and 2 poster sessions. All attendees are expected to actively participate in the GRS either by giving an oral presentation or presenting a poster. Therefore, all applications must include an abstract.

The Chairs will select speakers from abstracts submitted by May 5, 2017. Those applicants who are not chosen for talks and those who apply after the deadline to be considered for an oral presentation will be expected to present a poster. In order to participate, you must submit an application by the date indicated in the Application Deadline section above.

Related Meeting

This GRS will be held in conjunction with the "Staphylococcal Diseases" Gordon Research Conference (GRC). Those interested in attending both meetings must submit an application for the GRC in addition to an application for the GRS. Refer to the associated GRC program page for more information.

Meeting Program

Saturday
2:00 pm - 5:00 pmArrival and Check-in
3:30 pm - 3:45 pmIntroductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair
3:45 pm - 4:30 pmKeynote Session: Staphylococcal Metabolism
Discussion Leaders: Casey Gries (University of Nebraska Medical Center, USA) and Simon Heilbronner (University of Tuebingen, Germany)
3:45 pm - 4:20 pmKim Lewis (Northeastern University, USA)
"Staphylococcal Metabolism"
4:20 pm - 4:30 pmDiscussion
4:30 pm - 6:00 pmPoster Session
6:00 pmDinner
7:30 pm - 9:30 pmStaphylococcal Toxins and Virulence Factors / Host-Pathogen Interactions
Discussion Leaders: Emma Boldock (University of Sheffield, United Kingdom), Aimee Wilde (Vanderbilt University, USA), Deena Altman (Icahn School of Medicine at Mount Sinai, USA) and Kyle Buchan (University of Sheffield, United Kingdom)
7:30 pm - 7:45 pmXiaogang Wang (Brigham and Women's Hospital / Harvard Medical School, USA)
"Genetically-Engineered Staphylococcus aureus Extracellular Vesicles Provide Protective Efficacy in a Murine Sepsis Model"
7:45 pm - 7:50 pmDiscussion
7:50 pm - 8:05 pmSarah Baines (University of Melbourne, Australia)
"Convergent Adaptation of qacA-Containing Plasmids Within a Prevalent Hospital Lineage of Methicillin-Resistant Staphylococcus aureus Associated with Enhanced Chlorhexidine Tolerance"
8:05 pm - 8:10 pmDiscussion
8:10 pm - 8:25 pmSeema Joshi (Jawaharlal Nehru University, India)
"Novel Miniature Lipo-Peptidomimetics with Potency Against Planktonic and Biofilm Embedded Methicillin-Resistant Staphylococcus aureus"
8:25 pm - 8:30 pmDiscussion
8:30 pm - 8:45 pmJulia Uebele (Paul Ehrlich Institute, Germany)
"(Re-)Balancing of T Cell Memory to Staphylococcus aureus by Delivery of In Vitro Transcribed Antigens"
8:45 pm - 8:50 pmDiscussion
8:50 pm - 9:05 pmRob van Dalen (University Medical Center Utrecht, The Netherlands)
"The C-Type Lectin Receptor Langerin on Skin Langerhans Cells Interacts with Wall Teichoic Acid of Staphylococcus aureus"
9:05 pm - 9:10 pmDiscussion
9:10 pm - 9:25 pmSheila Thomas (Center for Infectious and Inflammatory Diseases, Texas A&M Institute of Biosciences & Technology, USA)
"Staphylococcus aureus von-Willebrand Factor-Binding Protein Interacts with Fibrinogen via Unique Binding Sites"
9:25 pm - 9:30 pmDiscussion
Sunday
7:30 am - 8:30 amBreakfast
9:00 am - 11:00 amStaphylococcal Metabolism / In Vivo Staphylococcal Disease Models
Discussion Leaders: Mariya Goncheva (The Roslin Institute, University of Edinburgh, United Kingdom), Amy Richards (University of Edinbugh, United Kingdom), Wenqi Yu (University of Chicago, USA) and Seema Joshi (Jawaharlal Nehru University, India)
9:00 am - 9:15 amAimee Wilde (Vanderbilt University, USA)
"The Skeletal Environment Mediates Staphylococcus aureus Metabolic Processes In Vivo"
9:15 am - 9:20 amDiscussion
9:20 am - 9:35 amChristopher Schuster (Imperial College London, United Kingdom)
"TN-seq Reveals Salt Stress Tolerance Genes in Staphylococcus aureus"
9:35 am - 9:40 amDiscussion
9:40 am - 9:55 amMcKenzie Lehman (University of Nebraska Medical Center, USA)
"Amino Acid Metabolism Is Important During a Staphylococcus aureus Skin Abscess Infection"
9:55 am - 10:00 amDiscussion
10:00 am - 10:15 amKyle Buchan (University of Sheffield, United Kingdom)
"Building a Humanised C5a Receptor Model of Staphylococcus aureus Infection"
10:15 am - 10:20 amDiscussion
10:20 am - 10:35 amRachel Kratofil (University of Calgary, Canada)
"Investigating a Mechanism of Monocyte Conversion During a Localized Staphylococcus aureus Skin Infection"
10:35 am - 10:40 amDiscussion
10:40 am - 10:55 amKayan Tam (New York University School of Medicine, USA)
"Fighting Toxins with Toxins - Exploiting the Leukocidins as Potential Targets for Anti-Staphylococcus aureus Vaccine"
10:55 am - 11:00 amDiscussion
11:00 am - 12:30 pmPoster Session

Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pmLunch
1:30 pm - 2:30 pmMentorship Component: Career Panel
Discussion Leaders: William Beavers (Vanderbilt University, USA) and Christopher Schuster (Imperial College London, United Kingdom)
1:30 pm - 2:30 pmPanel Discussion
"Career Development"
  • Jim Cassat (Vanderbilt University Medical Center, USA)
  • Rachel McLoughlin (Trinity College, Dublin, Ireland)
  • Amanda Oglesby-Sherrouse (University of Maryland, Baltimore, USA)
  • Bret Sellman (MedImmune, LLC, USA)
2:30 pm - 3:00 pmEvaluation Period
Fill in GRS Evaluation Forms
3:00 pmSeminar Concludes
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