Gordon Research Conferences
Meeting Details

Staphylococcal Diseases (GRS)
Gordon Research Seminar

Staphylococci at the Host-Pathogen Interface


August 5-6, 2017


Waterville Valley
Waterville Valley, NH


Casey M. Gries & William Beavers

Meeting Description

The Gordon Research Seminar on Staphylococcal Diseases is a unique forum for graduate students, post-docs, and other scientists with comparable levels of experience and education to present and exchange new data and cutting edge ideas.

This meeting will explore Staphylococci at the host-pathogen interface looking at both the bacterial and host responses during infection. Topics that will be presented include toxin generation, metabolic and signaling changes, and new models to study disease in vivo. The two-day seminar will include cutting-edge research presentations from trainees in the field as well as a mentorship panel featuring prominent scientists from academia, industry, and clinical settings.

Related Meeting

This GRS was held in conjunction with the "Staphylococcal Diseases" Gordon Research Conference (GRC). Refer to the associated GRC program page for more information.


Meeting Program

2:00 pm - 5:00 pmArrival and Check-in
3:30 pm - 3:45 pmIntroductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair
3:45 pm - 4:30 pmKeynote Session: Life and Death of Persister Cells
Discussion Leaders: Casey Gries (University of Nebraska Medical Center, USA) and Simon Heilbronner (University of Tuebingen, Germany)
3:45 pm - 4:20 pmKim Lewis (Northeastern University, USA)
"Life and Death of Persister Cells"
4:20 pm - 4:30 pmDiscussion
4:30 pm - 6:00 pmPoster Session
6:00 pmDinner
7:30 pm - 9:30 pmStaphylococcal Toxins and Virulence Factors / Host-Pathogen Interactions
Discussion Leaders: Emma Boldock (University of Sheffield, United Kingdom), Aimee Wilde (Vanderbilt University, USA), Deena Altman (Icahn School of Medicine at Mount Sinai, USA) and Kyle Buchan (University of Sheffield, United Kingdom)
7:30 pm - 7:45 pmXiaogang Wang (Brigham and Women's Hospital / Harvard Medical School, USA)
"Biogenesis of Extracellular Vesicles from S. aureus and Their Application as a Vaccine Platform"
7:45 pm - 7:50 pmDiscussion
7:50 pm - 8:05 pmSarah Baines (University of Melbourne, Australia)
"Convergent Adaptation of qacA-Containing Plasmids Within a Prevalent Hospital Lineage of Methicillin-Resistant Staphylococcus aureus Associated with Enhanced Chlorhexidine Tolerance"
8:05 pm - 8:10 pmDiscussion
8:10 pm - 8:25 pmEvelien Berends (New York University School of Medicine, USA)
"Staphylococcus aureus Targets Dendritic Cells and Hinders Development of Adaptive Immunity via Leukocidin AB"
8:25 pm - 8:30 pmDiscussion
8:30 pm - 8:45 pmJulia Uebele (Paul Ehrlich Institute, Germany)
"(Re-)Balancing of T Cell Memory to Staphylococcus aureus by Delivery of In Vitro Transcribed Antigens"
8:45 pm - 8:50 pmDiscussion
8:50 pm - 9:05 pmRob van Dalen (University Medical Center Utrecht, The Netherlands)
"The C-Type Lectin Receptor Langerin on Skin Langerhans Cells Interacts with Wall Teichoic Acid of Staphylococcus aureus"
9:05 pm - 9:10 pmDiscussion
9:10 pm - 9:25 pmSheila Thomas (Center for Infectious and Inflammatory Diseases, Texas A&M Institute of Biosciences & Technology, USA)
"Staphylococcus aureus von-Willebrand Factor-Binding Protein Interacts with Fibrinogen via Unique Binding Sites"
9:25 pm - 9:30 pmDiscussion
7:30 am - 8:30 amBreakfast
9:00 am - 11:00 amStaphylococcal Metabolism / In Vivo Staphylococcal Disease Models
Discussion Leaders: Mariya Goncheva (The Roslin Institute, University of Edinburgh, United Kingdom), Amy Richards (University of Edinbugh, United Kingdom), Wenqi Yu (University of Chicago, USA) and Jessica Sheldon (Vanderbilt University Medical Center, USA)
9:00 am - 9:15 amAimee Wilde (Vanderbilt University, USA)
"The Skeletal Environment Mediates Staphylococcus aureus Metabolic Processes In Vivo"
9:15 am - 9:20 amDiscussion
9:20 am - 9:35 amChristopher Schuster (Imperial College London, United Kingdom)
"TN-seq Reveals Salt Stress Tolerance Genes in Staphylococcus aureus"
9:35 am - 9:40 amDiscussion
9:40 am - 9:55 amMcKenzie Lehman (University of Nebraska Medical Center, USA)
"Amino Acid Metabolism Is Important During a Staphylococcus aureus Skin Abscess Infection"
9:55 am - 10:00 amDiscussion
10:00 am - 10:15 amKyle Buchan (University of Sheffield, United Kingdom)
"Building a Humanised C5a Receptor Model of Staphylococcus aureus Infection"
10:15 am - 10:20 amDiscussion
10:20 am - 10:35 amRachel Kratofil (University of Calgary, Canada)
"Investigating a Mechanism of Monocyte Conversion During a Localized Staphylococcus aureus Skin Infection"
10:35 am - 10:40 amDiscussion
10:40 am - 10:55 amKayan Tam (New York University School of Medicine, USA)
"Fighting Toxins with Toxins - Exploiting the Leukocidins as Potential Targets for Anti-Staphylococcus aureus Vaccine"
10:55 am - 11:00 amDiscussion
11:00 am - 12:30 pmPoster Session

Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pmLunch
1:30 pm - 2:30 pmMentorship Component: Career Panel
Discussion Leaders: William Beavers (Vanderbilt University, USA) and Christopher Schuster (Imperial College London, United Kingdom)
1:30 pm - 2:30 pmPanel Discussion
"Career Development"
  • Jim Cassat (Vanderbilt University Medical Center, USA)
  • Bettina Loeffler (Jena University Hospital, Germany)
  • Amanda Oglesby-Sherrouse (University of Maryland, Baltimore, USA)
  • Bret Sellman (MedImmune, LLC, USA)
2:30 pm - 3:00 pmEvaluation Period
Fill in GRS Evaluation Forms
3:00 pmSeminar Concludes

Funding for this conference was made possible by 1 R13 AI131540-01 from the National Institute of Allergy and Infectious Diseases. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.
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