SUNDAY |
2:00 pm - 8:00 pm | Arrival and Check-in |
6:00 pm | Dinner |
7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff and Chairs Roberto Bruzzone (HKU-Pasteur Research Pole) & Lisa FP Ng (Singapore Immunology Network - A*STAR) |
7:40 pm - 9:30 pm | Challenges in infections of the nervous system |
7:40 pm - 8:00 pm | Discussion Leader: Diane Griffin (Johns Hopkins School of Public Health)
"Overview to session"
|
8:00 pm - 8:35 pm | Avindra Nath (NINDS)
"Challenges in the eradication of HIV from the brain"
|
8:35 pm - 8:45 pm | Discussion |
8:45 pm - 9:20 pm | Jun Wang (BGI Shenzhen)
"Explore the unexplored Omics world"
|
9:20 pm - 9:30 pm | Discussion |
MONDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Ways of invading the nervous system |
| Discussion Leader: Giampietro Schiavo (Cancer Research UK) |
9:00 am - 9:20 am | Giampietro Schiavo (Cancer Research UK)
"Signaling endosomes: a main gateway for the spreading of pathogens in the nervous system"
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9:20 am - 9:30 am | Discussion |
9:30 am - 9:55 am | Beate Sodeik (Institute of Virology, Hannover)
"Nuclear targeting of herpes simplex virus in epithelial and neuronal cells"
|
9:55 am - 10:05 am | Discussion |
10:05 am - 10:20 am | Christoph Konradt (University of Pennsylvania)
"Breaching the blood-brain barrier during toxoplasmosis" |
10:20 am - 10:30 am | Discussion |
10:30 am | Group Photo / Coffee Break |
11:00 am - 11:25 am | Chiara Zurzolo (Institut Pasteur)
"Tunneling nanotubes and spreading of prions and prion-like proteins in neurodegenerative diseases"
|
11:25 am - 11:35 am | Discussion |
11:35 am - 12:00 pm | Paul R. Gorry (Burnet Institute)
"Macrophage tropic HIV-1 variants from brain demonstrate alterations in the way their envelope glycoproteins engage CD4 and CCR5"
|
12:00 pm - 12:10 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Target cells of the nervous system and host-pathogen interactions |
| Discussion Leader: Lisa FP Ng (Singapore Immunology Network - SIGN) |
7:30 pm - 7:50 pm | Lisa FP Ng (Singapore Immunology Network - SIGN)
"Target cells and host-pathogen interactions in Chikungunya infection" |
7:50 pm - 7:55 pm | Discussion |
7:55 pm - 8:20 pm | Alexander Khromykh (University of Queensland)
"The role of noncoding viral RNAs in West Nile virus-host interactions and pathogenesis"
|
8:20 pm - 8:30 pm | Discussion |
8:30 pm - 8:45 pm | Dawn Weir (Uniformed Services University)
"Tropism and host factor dependence of virus entry mediated by Australian bat lyssavirus G glycoproteins"
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8:45 pm - 8:55 pm | Discussion |
8:55 pm - 9:20 pm | Chris Hunter (University of Pennsylvania)
"Imaging immunity to infection"
|
9:20 pm - 9:30 pm | Discussion |
TUESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Immune responses of the CNS to invasion by pathogens |
| Discussion Leader: Carol Reiss (New York University) |
9:00 am - 9:20 am | Carol Reiss (New York University)
"Tetherin is an IFN-inducible transmembrane protein which restricts VSV infection in neurons"
|
9:20 am - 9:30 am | Discussion |
9:30 am - 9:55 am | Christopher Broder (Uniformed Services University)
"Combating the Hendra and Nipah virus encephalitic zoonoses by passive and active immunization"
|
9:55 am - 10:05 am | Discussion |
10:05 am - 10:20 am | Anita Koshy (University of Arizona)
"Astrocytic TGFβ signaling fine tunes the brain's immune response to Toxoplasma gondii"
|
10:20 am - 10:30 am | Discussion |
10:30 am | Coffee Break |
11:00 am - 11:25 am | Eugene Major (National Institute of Neurological Disorders and Stroke)
"Presence of JC virus DNA in immune and nervous system cells in PML patients" |
11:25 am - 11:35 am | Discussion |
11:35 am - 11:50 am | Wei Wang (Wuhan Institute of Virology)
"Japanese encephalitis virus activates autophagy as a viral immune evasion strategy"
|
11:50 am - 12:00 pm | Discussion |
12:00 pm - 12:25 pm | Olaf Rotzschke (Singapore Immunology Network - A*STAR)
"Immunogenetics of multiple sclerosis"
|
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Mechanisms of pathogenesis: Cellular features |
| Discussion Leader: Mark T. Heise (University of North Carolina) |
7:30 pm - 7:50 pm | Mark T. Heise (University of North Carolina)
"Alphavirus determinants of neurovirulence"
|
7:50 pm - 7:55 pm | Discussion |
7:55 pm - 8:20 pm | Xavier Nassif (INSERM)
"Mechanism of the crossing of a bacterial pathogen, Neisseria meningitidis, through the blood brain barrier"
|
8:20 pm - 8:30 pm | Discussion |
8:30 pm - 8:45 pm | Alan Jackson (University of Manitoba)
"Rabies virus infection is a mitochondrial disorder"
|
8:45 pm - 8:55 pm | Discussion |
8:55 pm - 9:20 pm | Dorian McGavern (NIH)
"Dynamic insights into sterile and microbial immunity in the living brain"
|
9:20 pm - 9:30 pm | Discussion |
WEDNESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Mechanisms of pathogenesis: Clinical features |
| Discussion Leader: Laurent Renia (Singapore Immunology Network - A*STAR) |
9:00 am - 9:20 am | Laurent Renia (Singapore Immunology Network - A*STAR)
"Mysteries at the blood-brain barrier"
|
9:20 am - 9:30 am | Discussion |
9:30 am - 9:55 am | Tom Solomon (University of Liverpool)
"Lessons from the clinical features and pathogenesis of encephalitis"
|
9:55 am - 10:05 am | Discussion |
10:05 am - 10:20 am | Lauren O'Donnell (Duquesne University)
"Neuroprotective and cytotoxic roles for proinflammatory mediators in neonatal CNS infections"
|
10:20 am - 10:30 am | Discussion |
10:30 am | Coffee Break |
11:00 am - 11:25 am | Robert Wilkinson (Imperial College)
"Pathogenesis, presentation and management of neurological HIV-tuberculosis immune reconstitution inflammatory syndrome"
|
11:25 am - 11:35 am | Discussion |
11:35 am - 11:50 am | Victoria Baxter (Johns Hopkins School of Public Health)
"Neurological sequelae in a mouse model of alphavirus encephalomyelitis"
|
11:50 am - 12:00 pm | Discussion |
12:00 pm - 12:25 pm | Kum-Thong Wong (University of Malaya)
"Enterovirus 71 infection and neuropathogenesis"
|
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Experimental models of infections of the nervous system |
| Discussion Leader: John Fazakerley (The Pirbright Institute) |
7:30 pm - 7:50 pm | John Fazakerley (The Pirbright Institute)
"Semliki Forest virus infection of the mouse, a model of acute virus encephalitis and virus induced demyelination"
|
7:50 pm - 7:55 pm | Discussion |
7:55 pm - 8:20 pm | Krister Kristensson (Karolinska Institutet)
"Entry and growth control of African trypanosomes in the brain"
|
8:20 pm - 8:30 pm | Discussion |
8:30 pm - 8:45 pm | Carla Claser (Singapore Immunology Network - A*STAR)
"Role of interferon regulatory factor 3 (IRF3) in immunopathology and protection against experimental cerebral malaria"
|
8:45 pm - 8:55 pm | Discussion |
8:55 pm - 9:20 pm | Georges Grau (University of Sydney)
"Novel cellular cross-talks at the blood-brain barrier: microparticles as effectors of immunopathology"
|
9:20 pm - 9:30 pm | Discussion |
THURSDAY |
7:30 am - 8:30 am | Breakfast |
8:30 am - 9:00 am | Business Meeting |
| Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair |
9:00 am - 12:30 pm | Pathogen discovery in infections of the nervous system |
| Discussion Leader: Christian Drosten (University of Bonn) |
9:00 am - 9:20 am | Christian Drosten (University of Bonn)
"Overview to session"
|
9:20 am - 9:30 am | Discussion |
9:30 am - 9:55 am | Paul Newton (Mahosot Hospital)
"CNS infections in Laos"
|
9:55 am - 10:05 am | Discussion |
10:05 am | Coffee Break |
11:00 am - 11:25 am | Antoine Gessain (Institut Pasteur)
"Search for viral etiology in tropical CNS diseases: A long way from HTLV-1 associated myelopathy to varied encephalitis"
|
11:25 am - 11:35 am | Discussion |
11:35 am - 11:55 am | Marc Eloit (Institut Pasteur)
"Pathogen identification by high throughput sequencing in human encephalitis of unknown origin"
|
11:55 am - 12:05 pm | Discussion |
12:05 pm - 12:30 pm | General Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Ways to control infections of the nervous system: from field to bench to bed |
| Discussion Leader: Ben Berkhout (University of Amsterdam) |
4:00 pm - 4:20 pm | Ben Berkhout (University of Amsterdam)
"HIV-1 studies and how to control gene expression in the brain"
|
4:20 pm - 4:30 pm | Discussion |
4:30 pm - 4:45 pm | Pierre Talbot (Institut Armand-Frappier)
"Novel treatment with neuroprotective and antiviral properties against a neuroinvasive human respiratory virus"
|
4:45 pm - 4:55 pm | Discussion |
4:55 pm - 5:10 pm | Marc Lecuit (Institut Pasteur)
"The threat of infectious encephalitis in Southeast Asia - Improved diagnosis for improved management of infectious encephalitis"
|
5:10 pm - 5:20 pm | Discussion |
5:20 pm - 5:45 pm | Ronald J. Ellis (UCSD)
"New frontiers in the Neurology of HIV Infection"
|
5:45 pm - 6:00 pm | Discussion |
6:00 pm | Dinner |
FRIDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am | Departure |