Gordon Research Conferences
Meeting Details

Cornea, Biology & Pathobiology of the (GRS)
Gordon Research Seminar

Future Challenges and Directions of Ocular Surface Research
Note: This conference is currently known as "Cornea & Ocular Surface Biology & Pathology (GRS)".


February 27-28, 2016


Ventura Beach Marriott
Ventura, CA


Laura Contreras Ruiz & Jong Kook Park

Meeting Description

The Gordon Research Seminar on Biology and Pathobiology of the Cornea is a unique forum for graduate students, post-docs, and other scientists with comparable levels of experience and education to present and exchange new data and cutting edge ideas.

The focus of this meeting is to explore the latest developments in ocular surface research and to stimulate participants to identify the most relevant questions that need to be answered in the near future. Topics of discussion will cover the different components of the ocular surface, including cornea, conjunctiva, limbus, tear film, as well as meibomian and lacrimal glands, with regard to broad issues encompassing tissue homeostasis, development, engineering/regeneration/repair, stem cell regulation, infection/inflammation, innervation/pain/itch and novel future therapeutics. A mentoring session on how to critically evaluate the literature will complement the program.

Related Meeting

This GRS was held in conjunction with the "Cornea, Biology & Pathobiology of the" Gordon Research Conference (GRC). Refer to the associated GRC program page for more information.


Final Meeting Program

2:00 pm - 5:00 pmArrival and Check-in
3:30 pm - 3:45 pmIntroductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair
3:45 pm - 4:30 pmKeynote Session: Lab Experiment - How to Get Lab Techniques to Work?
Discussion Leaders: Shigeto Shimmura (Keio University School of Medicine, Japan) and Vivien Coulson-Thomas (University of Cincinnati, USA)
3:45 pm - 4:20 pmRobert Lavker (Northwestern University, USA)
"Lab Experiment: How to Get Lab Techniques to Work?"
4:20 pm - 4:30 pmDiscussion
4:30 pm - 6:00 pmPoster Session
6:00 pmDinner
7:30 pm - 9:30 pmAn Update on Ocular Surface Stem Cells
Discussion Leaders: Julie Daniels (UCL Institute of Ophthalmology, United Kingdom) and Andrew Hertsenberg (Massachusetts Eye and Ear Infirmary, Harvard Medical School, USA)
7:30 pm - 7:50 pmAlison Kuony (Institute of Biotechnology, University of Helsinki, Finland)
"Mechanisms and Molecular Regulation of Lacrimal Gland Morphogenesis and Maintenance"
7:50 pm - 8:00 pmDiscussion
8:00 pm - 8:20 pmGeraint Parfitt (University of California, Irvine, USA)
"Immunofluorescence Tomography of Limbal Epithelial Stem Cells"
8:20 pm - 8:30 pmDiscussion
8:30 pm - 8:45 pmSolja Kalha (University of Helsinki, Finland)
"The Role of Bmi1 in the Renewal of the Mouse Cornea Epithelium"
8:45 pm - 8:50 pmDiscussion
8:50 pm - 9:05 pmNihal Kaplan (Northwestern University, USA)
"Ephrin-A1/EphA2 Mediated Limbal-Corneal Epithelial Boundary Is Dependent on ADAM-10 Regulation of EGFR Signaling"
9:05 pm - 9:10 pmDiscussion
9:10 pm - 9:25 pmHan Peng (Northwestern University, USA)
"Autophagy, a Protective Factor in Limbal Epithelium, Is Positively Regulated by a MicroRNA Family"
9:25 pm - 9:30 pmDiscussion
7:30 am - 8:30 amBreakfast
9:00 am - 11:00 amOcular Surface Responses to Inflammation, Infection and Injury
Discussion Leaders: Stephen Sugrue (University of Florida, USA) and Obi Onochie (Boston University School of Medicine, USA)
9:00 am - 9:15 amTerry Coursey (Baylor College of Medicine, USA)
"IFN-Gamma Induced Unfolded Protein Response in Conjunctival Goblet Cells as Cause of Mucin Deficiency in Sjögren's Syndrome"
9:15 am - 9:20 amDiscussion
9:20 am - 9:40 amLaura Garcia-Posadas (Schepens Eye Research Institute / Massachusetts Eye and Ear, USA)
"Effect of IL-13 on Human Conjunctival Goblet Cells"
9:40 am - 9:50 amDiscussion
9:50 am - 10:05 amMartin Minns (Boston University, USA)
"The P2X7 Purinoreceptor in Corneal Epithelial Cell Migration After Injury"
10:05 am - 10:10 amDiscussion
10:10 am - 10:30 amSriniwas Sriram (Schepens Eye Research Institute / Massachusetts Eye and Ear, USA)
"Identifying the Role of PDGFRa in the Fibrotic Pathway of TGF-β3"
10:30 am - 10:40 amDiscussion
10:40 am - 10:55 amBing Xu (Wayne State University School of Medicine, USA)
"Expression and Functions of IL-24 and SOCS3 in Pseudomonas aeruginosa Keratitis in a C57BL/6 Mouse Model"
10:55 am - 11:00 amDiscussion
11:00 am - 12:30 pmPoster Session

Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pmLunch
1:30 pm - 2:30 pmMentorship Component: How to Succeed in Science - Circa 2015
Discussion Leaders: Darlene Dartt (Schepens Eye Research Institute, USA) and James Foster (Johns Hopkins University, USA)
1:30 pm - 1:50 pmRobert Lavker (Northwestern University, USA)
"Thought Experiment: How to Read Papers and Generate Ideas?"
1:50 pm - 2:00 pmDiscussion
2:00 pm - 2:20 pmDarlene Dartt (Schepens Eye Research Institute, USA)
"Taking the Pain Out of Grant Writing"
2:20 pm - 2:30 pmDiscussion
2:30 pm - 3:00 pmEvaluation Period
Fill in GRS Evaluation Forms
3:00 pmSeminar Concludes

Funding for this conference was made possible (in part) by 1R13 EY026341-01 from the National Eye Institute. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.
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