The Gordon Research Seminar on Biology and Pathobiology of the Cornea is a unique forum for graduate students, post-docs, and other scientists with comparable levels of experience and education to present and exchange new data and cutting edge ideas.
The focus of this meeting is to explore the latest developments in ocular surface research and to stimulate participants to identify the most relevant questions that need to be answered in the near future. Topics of discussion will cover the different components of the ocular surface, including cornea, conjunctiva, limbus, tear film, as well as meibomian and lacrimal glands, with regard to broad issues encompassing tissue homeostasis, development, engineering/regeneration/repair, stem cell regulation, infection/inflammation, innervation/pain/itch and novel future therapeutics. A mentoring session on how to critically evaluate the literature will complement the program.
This GRS was held in conjunction with the "Cornea, Biology & Pathobiology of the" Gordon Research Conference (GRC)
. Refer to the associated GRC program page
for more information.
Final Meeting Program
|2:00 pm - 5:00 pm||Arrival and Check-in|
|3:30 pm - 3:45 pm||Introductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair|
|3:45 pm - 4:30 pm||Keynote Session: Lab Experiment - How to Get Lab Techniques to Work?|
|Discussion Leaders: Shigeto Shimmura (Keio University School of Medicine, Japan) and Vivien Coulson-Thomas (University of Cincinnati, USA)|
|3:45 pm - 4:20 pm||Robert Lavker (Northwestern University, USA)|
"Lab Experiment: How to Get Lab Techniques to Work?"
|4:20 pm - 4:30 pm||Discussion|
|4:30 pm - 6:00 pm||Poster Session|
|7:30 pm - 9:30 pm||An Update on Ocular Surface Stem Cells|
|Discussion Leaders: Julie Daniels (UCL Institute of Ophthalmology, United Kingdom) and Andrew Hertsenberg (Massachusetts Eye and Ear Infirmary, Harvard Medical School, USA)|
|7:30 pm - 7:50 pm||Alison Kuony (Institute of Biotechnology, University of Helsinki, Finland)|
"Mechanisms and Molecular Regulation of Lacrimal Gland Morphogenesis and Maintenance"
|7:50 pm - 8:00 pm||Discussion|
|8:00 pm - 8:20 pm||Geraint Parfitt (University of California, Irvine, USA)|
"Immunofluorescence Tomography of Limbal Epithelial Stem Cells"
|8:20 pm - 8:30 pm||Discussion|
|8:30 pm - 8:45 pm||Solja Kalha (University of Helsinki, Finland)|
"The Role of Bmi1 in the Renewal of the Mouse Cornea Epithelium"
|8:45 pm - 8:50 pm||Discussion|
|8:50 pm - 9:05 pm||Nihal Kaplan (Northwestern University, USA)|
"Ephrin-A1/EphA2 Mediated Limbal-Corneal Epithelial Boundary Is Dependent on ADAM-10 Regulation of EGFR Signaling"
|9:05 pm - 9:10 pm||Discussion|
|9:10 pm - 9:25 pm||Han Peng (Northwestern University, USA)|
"Autophagy, a Protective Factor in Limbal Epithelium, Is Positively Regulated by a MicroRNA Family"
|9:25 pm - 9:30 pm||Discussion|
|7:30 am - 8:30 am||Breakfast|
|9:00 am - 11:00 am||Ocular Surface Responses to Inflammation, Infection and Injury|
|Discussion Leaders: Stephen Sugrue (University of Florida, USA) and Obi Onochie (Boston University School of Medicine, USA)|
|9:00 am - 9:15 am||Terry Coursey (Baylor College of Medicine, USA)|
"IFN-Gamma Induced Unfolded Protein Response in Conjunctival Goblet Cells as Cause of Mucin Deficiency in Sjögren's Syndrome"
|9:15 am - 9:20 am||Discussion|
|9:20 am - 9:40 am||Laura Garcia-Posadas (Schepens Eye Research Institute / Massachusetts Eye and Ear, USA)|
"Effect of IL-13 on Human Conjunctival Goblet Cells"
|9:40 am - 9:50 am||Discussion|
|9:50 am - 10:05 am||Martin Minns (Boston University, USA)|
"The P2X7 Purinoreceptor in Corneal Epithelial Cell Migration After Injury"
|10:05 am - 10:10 am||Discussion|
|10:10 am - 10:30 am||Sriniwas Sriram (Schepens Eye Research Institute / Massachusetts Eye and Ear, USA)|
"Identifying the Role of PDGFRa in the Fibrotic Pathway of TGF-β3"
|10:30 am - 10:40 am||Discussion|
|10:40 am - 10:55 am||Bing Xu (Wayne State University School of Medicine, USA)|
"Expression and Functions of IL-24 and SOCS3 in Pseudomonas aeruginosa Keratitis in a C57BL/6 Mouse Model"
|10:55 am - 11:00 am||Discussion|
|11:00 am - 12:30 pm||Poster Session|
|Coffee will be served in the poster area from 11:00 am - 11:30 am|
|1:30 pm - 2:30 pm||Mentorship Component: How to Succeed in Science - Circa 2015|
|Discussion Leaders: Darlene Dartt (Schepens Eye Research Institute, USA) and James Foster (Johns Hopkins University, USA)|
|1:30 pm - 1:50 pm||Robert Lavker (Northwestern University, USA)|
How to Read Papers and Generate Ideas?"
|1:50 pm - 2:00 pm||Discussion|
|2:00 pm - 2:20 pm||Darlene Dartt (Schepens Eye Research Institute, USA)|
"Taking the Pain Out of Grant Writing"
|2:20 pm - 2:30 pm||Discussion|
|2:30 pm - 3:00 pm||Evaluation Period|
|Fill in GRS Evaluation Forms|
|3:00 pm||Seminar Concludes|
Funding for this conference was made possible (in part) by 1R13 EY026341-01 from the National Eye Institute. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.