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Immunochemistry & Immunobiology (GRS)
Gordon Research Seminar

Technologies and Discoveries Advancing the Frontiers of Immunology

Dates

June 18-19, 2016

Location

Renaissance Tuscany Il Ciocco
Lucca (Barga), Italy

Organizers

Chairs:
Robert Kimmerling & Gregory L. Szeto

Meeting Description

The Gordon Research Seminar on Immunochemistry and Immunobiology is a unique forum for graduate students, post-docs, and other scientists with comparable levels of experience and education to present and exchange new data and cutting edge ideas.

The focus of this meeting will include novel approaches towards single-cell immunobiology, connecting molecular mechanisms to cellular function and diseases, platforms for engineering immune function in disease, and high-dimensional analytics for defining immune function and in immunodiagnostics.

An equally important aim of the GRS is to leverage the experience of senior investigators to jump-start the careers of the next generation. A panel consisting of senior and junior scientists from academia and biotech will outline key components of success and survival in science including technical skill development, strategic decision-making and learning from inevitable failures in the high-stakes world of research.

Related Meeting

This GRS was held in conjunction with the "Immunochemistry & Immunobiology" Gordon Research Conference (GRC). Refer to the associated GRC program page for more information.

Contributors

Final Meeting Program

Saturday
1:30 pm - 4:30 pmArrival and Check-in
3:00 pm - 3:15 pmIntroductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair
3:15 pm - 4:00 pmKeynote Session: Immunological Synapses Between Cells and Scientists
Our work on the immunological synapse has evolved as a series of collaborations that bring together diverse skill sets to solve a problem of how immune cells communicate. Personally, my graduate studies on intercellular adhesion molecule-1, my post-doctoral work on lysosomal biogenesis and my independent work on the immunological synapse, have all had key collaborative elements to reach the highest impact. I will discuss how collaboration at all career stages can move science and your career forward. The discussion will emphasize the importance of carefully selecting projects and the equal importance of taking the projects that have been undertaken to the best possible conclusions.
Discussion Leader: Robert Kimmerling (Massachusetts Institute of Technology, USA)
3:15 pm - 3:45 pmMichael Dustin (Kennedy Institute of Rheumatology, University of Oxford, United Kingdom)
"Immunological Synapses Between Cells and Scientists"
3:45 pm - 4:00 pmDiscussion
4:00 pm - 5:30 pmPoster Session
5:30 pm - 7:30 pmNovel Technologies and Methods for Investigating the Immune System
Discussion Leader: Kaitlyn Sadtler (Johns Hopkins University, USA)
5:30 pm - 5:50 pmTodd Gierahn (Massachusetts Institute of Technology, USA)
"Deep Profiling of the Proteome and Transcriptome of Sparse Clinical Samples at Single Cell Resolution"
5:50 pm - 6:00 pmDiscussion
6:00 pm - 6:20 pmCassie Bryan (University of Washington, USA)
"Computational Design of Small Protein Inhibitors Targeting PD-1 for Use in an Adoptive Macrophage Immunotherapy"
6:20 pm - 6:30 pmDiscussion
6:30 pm - 6:50 pmSimon Friedensohn (ETH Zurich, Switzerland)
"Correlations of Antibody Response Phenotype to Genotype Revealed by Molecular Amplification Fingerprinting"
6:50 pm - 7:00 pmDiscussion
7:00 pm - 7:20 pmMichal Polonsky (Weizmann Institute of Science, Israel)
"Social T Cells: Dissecting the Role of T-T Interactions on Cellular Fates"
7:20 pm - 7:30 pmDiscussion
8:00 pmDinner
Sunday
7:30 am - 8:30 amBreakfast
9:00 am - 11:00 amAdvances in Molecular and Translational Immunology
Discussion Leader: Todd Gierahn (Massachusetts Institute of Technology, USA)
9:00 am - 9:20 amKaitlyn Sadtler (Johns Hopkins University, USA)
"Th2 T Cells Are Required for Biomaterial-Mediated Muscle Regeneration in a Murine Model of Volumetric Muscle Loss"
9:20 am - 9:30 amDiscussion
9:30 am - 9:50 amNienke Moret (Harvard Medical School, USA)
"Controlling T Cell Activation by Modification of Signaling Pathways with Small Molecules"
9:50 am - 10:00 amDiscussion
10:00 am - 10:20 amThuy-Ai Nguyen (National Institute of Environmental Health Sciences, NIH, USA)
"p53 Binding and Regulation of Immune Response Genes in Human Primary T-Lymphocytes"
10:20 am - 10:30 amDiscussion
10:30 am - 10:50 amLiraz Galia (Weizmann Institute of Science, Israel)
"Neutralization of Ly6C+ Pro-Inflammatory Monocytes by Targeting TLR2 Dimerization Ameliorates Acute Colitis"
10:50 am - 11:00 amDiscussion
11:00 am - 12:30 pmPoster Session

Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pmLunch
1:30 pm - 2:30 pmMentorship Component: Panel Discussion
Discussion Leader: Gregory Szeto (University of Maryland, Baltimore County, USA)
1:30 pm - 2:30 pmPanel Discussion
"Discussing Emergent Concepts in Immunology"
  • Yasmine Belkaid (National Institute of Allergy and Infectious Diseases, NIH, USA)
  • Ian Kaplan (Adaptive Biotechnologies, USA)
  • Ioana Visan (Nature Publishing Group, USA)
2:30 pm - 3:00 pmEvaluation Period
Fill in GRS Evaluation Forms
3:00 pmSeminar Concludes

Funding for this conference was made possible in part by 1 R13 AI124614-01 from the National Institute of Allergy and Infectious Diseases. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.
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