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Marine Natural Products (GRS)
Gordon Research Seminar

Innovative Approaches for the Discovery and Exploitation of Marine Natural Products

Dates

March 5-6, 2016

Location

Four Points Sheraton / Holiday Inn Express
Ventura, CA

Organizers

Chairs:
Katherine R. Duncan & Micheal C. Wilson

Meeting Description

The Gordon Research Seminar on Marine Natural Products is a unique forum for graduate students, post-docs, and other scientists with comparable levels of experience and education to present and exchange new data and cutting edge ideas.

This meeting will focus on the presentation of innovative, high quality research by early career researchers on diverse topics that encompass the field of marine natural products. Presentations and discussions will highlight key insights, innovative approaches and advances in the field of marine natural products. Abstracts that encompass a cross-disciplinary approach with a focus on informed bioprospecting, technological advances, molecular characterization, genome mining, biosynthesis, chemical ecology and chemical biology are strongly encouraged.

Related Meeting

This GRS was held in conjunction with the "Marine Natural Products" Gordon Research Conference (GRC). Refer to the associated GRC program page for more information.

Contributors

Final Meeting Program

Saturday
2:00 pm - 5:00 pmArrival and Check-in
3:30 pm - 3:45 pmIntroductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair
3:45 pm - 4:30 pmKeynote Session: Integrated Profiling Strategies in Natural Products Research
Discussion Leader: Navid Adnani (University of Wisconsin-Madison, USA)
3:45 pm - 4:15 pmRoger Linington (Simon Fraser University, Canada)
"Towards the Universal Characterization of Natural Products Libraries; Integrated Chemical and Biological Profiling Strategies in Natural Products Research"
4:15 pm - 4:30 pmDiscussion
4:30 pm - 6:00 pmPoster Session
6:00 pmDinner
7:30 pm - 9:30 pmNew Frontiers in Chemistry and Biosynthesis
Discussion Leaders: Andrew Buller (California Institute of Technology, USA) and Abrahim El Gamal (University of California, San Diego, USA)
7:30 pm - 7:50 pmAnne-Catrin Letzel (Scripps Institution of Oceanography, University of California, San Diego, USA)
"The Secondary Metabolome of the Genus Salinispora"
7:50 pm - 8:00 pmDiscussion
8:00 pm - 8:20 pmCristina Alexandru (University of Aberdeen, United Kingdom)
"Exploring RiPP Biosynthetic Pathways in a Quest for a Novel Macrocyclase with Improved Catalytic Properties"
8:20 pm - 8:30 pmDiscussion
8:30 pm - 8:50 pmAnna Vagstad (ETH Zurich, Switzerland)
"Mechanistic Insights into Radical-Mediated Amino Acid Epimerization in Proteusin Peptide Natural Products"
8:50 pm - 9:00 pmDiscussion
9:00 pm - 9:20 pmMichelle Schorn (Scripps Institution of Oceanography, University of California, San Diego, USA)
"From Genes to Molecules: Accessing the Genetic Potential for Secondary Metabolite Production in Rare Marine Actinomycetes"
9:20 pm - 9:30 pmDiscussion
Sunday
7:30 am - 8:30 amBreakfast
9:00 am - 11:00 amInformed Bioprospecting: Environmental and Ecological Impacts
Discussion Leaders: Agustina Undabarrena (Universidad Tecnica Federico Santa Maria, Chile) and Silke Reiter (Swiss Federal Institute of Technology, Switzerland)
9:00 am - 9:20 amBrett Covington (Vanderbilt University, USA)
"Mapping Microbial Natural Product Responses to Activation Stimuli"
9:20 am - 9:30 amDiscussion
9:30 am - 9:50 amLeesa Habener (Griffith University, Australia)
"Comparing Chemical and Genetic Diversity of Marine Sponges from the Great Barrier Reef, Australia Using LC-MS and NMR Spectroscopic Chemical Fingerprints"
9:50 am - 10:00 amDiscussion
10:00 am - 10:20 amKazuya Fukuhara (The University of Tokyo, Japan)
"Isolation and Structure Elucidation of Nazumazoles A-F from the Marine Sponge Theonella swinhoei"
10:20 am - 10:30 amDiscussion
10:30 am - 10:50 amRemington Poulin (Georgia Institute of Technology, USA)
"1H NMR-Based Metabolomics Reveals Chemical Basis for Predator Sensing by Marine Invertebrates"
10:50 am - 11:00 amDiscussion
11:00 am - 12:30 pmPoster Session

Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pmLunch
1:30 pm - 2:30 pmTechnological Advances for Innovative Discovery
Discussion Leader: Emily Mevers (Harvard Medical School, USA)
1:30 pm - 1:50 pmEric Helfrich (Institute of Microbiology, ETH Zürich, Switzerland)
"A Genome Mining Tool for the Identification and Structure Prediction of Trans-AT PKS-Derived Polyketides"
1:50 pm - 2:00 pmDiscussion
2:00 pm - 2:20 pmTal Luzzatto-Knaan (University of California, San Diego, USA)
"Chemodiversity Based Cartography of Natural Products from Marine Communities"
2:20 pm - 2:30 pmDiscussion
2:30 pm - 3:00 pmEvaluation Period
Fill in GRS Evaluation Forms
3:00 pmSeminar Concludes

Funding for this conference was made possible (in part) by 1R13AT009147-01 from the National Center for Complementary and Integrative Health (NCCIH). The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.
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