|2:00 pm - 5:00 pm||Arrival and Check-in|
|3:30 pm - 3:45 pm||Introductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair|
|3:45 pm - 4:30 pm||Keynote Session: Interdisciplinary Approaches to Musculoskeletal Research|
|The goal of this session
is to introduce early investigators to the Gordon Conference and the theme of
both the GRS and the GRC to come. In particular our meeting focus (Moving Forward in Musculoskeletal Biology and
Bioengineering) will introduce and develop the concept of
cross-disciplinary studies, networking and strategies for early investigators
to develop strong and meaningful research careers and programs. A Keynote
Lecture will be presented by Dr. Ronen Schweitzer of the Oregon Health Sciences
University and Dr. Alice Huang of Mount Sinai. Drs. Schweitzer and Huang will
discuss their career paths in biology and engineering, respectively, their
interdisciplinary research programs, and the role that mentorship has played in
|Discussion Leaders: Anne Gingery (Mayo Clinic, USA) and Megan Killian (University of Delaware, USA)|
|3:45 pm - 4:00 pm||Ronen Schweitzer (Shriners Research Center, Portland, USA)|
"Of Flies and Mice, Biologists and Engineers - A Tendon Story"
|4:00 pm - 4:05 pm||Discussion|
|4:05 pm - 4:20 pm||Alice Huang (Icahn School of Medicine at Mount Sinai, USA)|
"Integrating Developmental Biology and Tissue Engineering Approaches for Tendon Regeneration"
|4:20 pm - 4:30 pm||Discussion|
|4:30 pm - 6:00 pm||Poster Session|
|7:30 pm - 9:30 pm||Musculoskeletal Crosstalk (and Beyond)|
|Discussion Leaders: Oliver Gardner (Boston Children's Hospital, USA) and Rachel Nordberg (University of North Carolina at Chapel Hill / North Carolina State University, USA)|
|7:30 pm - 7:45 pm||Neta Felsenthal (Weizmann Institute of Science, Israel)|
"Development on the Move: Population Replacement in Migrating Entheses"
|7:45 pm - 7:50 pm||Discussion|
|7:50 pm - 8:05 pm||Georg Feichtinger (University of Leeds, United Kingdom)|
"Novel, Multi-Phasic Gene-Activated Matrices for Gradient-Based Multi Gene Delivery"
|8:05 pm - 8:10 pm||Discussion|
|8:10 pm - 8:25 pm||Riccardo Gottardi (University of Pittsburgh, USA)|
"An Osteochondral Microphysiological System to Study Cartilage-Bone Interaction in Native Tissues and Engineered Model Constructs"
|8:25 pm - 8:30 pm||Discussion|
|8:30 pm - 8:45 pm||Jakob Sieker (Boston Children's Hospital, Harvard Medical School, USA)|
"Loss of Articular Cartilage Glycosaminoglycans in Post-Traumatic Osteoarthritis Is Associated with the Activation of Pathways Related to Cartilage and Bone Formation in the Synovium"
|8:45 pm - 8:50 pm||Discussion|
|8:50 pm - 9:05 pm||Claire McLeod (University of Pennsylvania, USA)|
"Single-Cell Molecular and Microenvironmental Heterogeneity in Differentiating Stem Cells"
|9:05 pm - 9:10 pm||Discussion|
|9:10 pm - 9:25 pm||Jennifer Robinson (Columbia University, USA)|
"Estrogen Promotes Chondrogenesis and Maintains Homeostasis in the Temporomandibular Joint Fibrocartilage via Estrogen Receptor Alpha"
|9:25 pm - 9:30 pm||Discussion|
|7:30 am - 8:30 am||Breakfast|
|9:00 am - 11:00 am||Musculoskeletal Injury and Strategies for Repair|
|Discussion Leaders: Bashar Alkhatib (University of Alabama at Birmingham, USA) and David Browe (Trinity College Dublin, Ireland)|
|9:00 am - 9:15 am||Karen Bulaklak (The University of North Carolina at Chapel Hill, USA)|
"Defining the Role of microRNA-206 in Duchenne Muscular Dystrophy"
|9:15 am - 9:20 am||Discussion|
|9:20 am - 9:35 am||Alvin Wong (University of California, San Francisco, USA)|
"The Effect of Motor Denervation on Muscle Satellite Cells"
|9:35 am - 9:40 am||Discussion|
|9:40 am - 9:55 am||Brian Diekman (University of North Carolina at Chapel Hill, USA)|
"Transcriptional Regulation of the Aging Biomarker p16INK4a and Its Role in Mediating Chondrocyte Senescence During Osteoarthritis"
|9:55 am - 10:00 am||Discussion|
|10:00 am - 10:15 am||Grainne Cunniffe (Trinity College Dublin, Ireland)|
"Cartilage ECM Derived Biomaterials for Joint Regeneration"
|10:15 am - 10:20 am||Discussion|
|10:20 am - 10:35 am||Julianne Huegel (University of Pennsylvania, USA)|
"Effects of Autologous Tenocyte-Seeded Nanofibrous Scaffolds in Rotator Cuff Repair Are Age-Dependent"
|10:35 am - 10:40 am||Discussion|
|10:40 am - 10:55 am||Rose Long (Mount Sinai Hospital, USA)|
"Induction of Cd146+ Phenotype by Tgfb1 from Human Annulus Fibrosus Cells for Annulus Repair"
|10:55 am - 11:00 am||Discussion|
|11:00 am - 12:30 pm||Poster Session|
|Coffee will be served in the poster area from 11:00 am - 11:30 am|
|1:30 pm - 2:30 pm||Mentorship Component: Career Panel|
session will provide of forum for early career investigators to discuss career
options and paths, including Academia, National Laboratories, the NIH, Clinical
Practice, and Industry.|
|Discussion Leader: Dana Cairns (Tufts University, USA)|
|1:30 pm - 2:30 pm||Panel Discussion|
|"Panel Discussion Career Options and Paths, Including Academia, National Laboratories, the NIH, Clinical Practice, and Industry"|
- Louis Defrate (Duke University Medical Center, USA)
- Peter Johnson (MedSurgPI, LLC, USA)
- Yasaman Shirazi (NASA Ames Research Center, USA)
- Fei Wang (National Institutes of Health, USA)
|2:30 pm - 3:00 pm||Evaluation Period|
|Fill in GRS Evaluation Forms|
|3:00 pm||Seminar Concludes|