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Oxygen Radicals (GRS)
Gordon Research Seminar

Reactive Oxygen Species in Health and Disease

Dates

February 6-7, 2016

Location

Ventura Beach Marriott
Ventura, CA

Organizers

Chairs:
Divya Vasudevan & Daniel C J. Ferguson

Meeting Description

The Gordon Research Seminar on Oxygen Radicals is a unique forum for graduate students, post-docs, and other scientists with comparable levels of experience and education to present and exchange new data and cutting edge ideas.

The goal of this meeting is to evaluate novel developments uncovering the roles of ROS in the maintenance of physiological processes as well as in the propagation of pathologies. Advancements in scientific research and methodological tools are expected to be discussed.

Related Meeting

This GRS was held in conjunction with the "Oxygen Radicals" Gordon Research Conference (GRC). Refer to the associated GRC program page for more information.

Contributors

Final Meeting Program

Saturday
2:00 pm - 5:00 pmArrival and Check-in
3:30 pm - 3:45 pmIntroductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair
3:45 pm - 4:30 pmKeynote Session: Redox Processes in Cancer
Discussion Leaders: Daniel Ferguson (University of Exeter Medical School, United Kingdom) and Divya Vasudevan (Weill Cornell Medical College, USA)
3:45 pm - 4:15 pmDavid Wink (National Cancer Institute, NIH, USA)
"Nitric Oxide and Cancer: NOS2 Role in Driving Poor Prognosis in ER(-) Breast Cancer"
4:15 pm - 4:30 pmDiscussion
4:30 pm - 6:00 pmPoster Session
6:00 pmDinner
7:30 pm - 9:30 pmDevelopments in ROS Profiling and Its Roles in Cellular Redox Processes
Discussion Leaders: Ana Denicola (University of the Republic, Uruguay) and Rakesh Patel (University of Alabama at Birmingham, USA)
7:30 pm - 7:50 pmKlaus Koren (University of Copenhagen, Denmark)
"Rechargeable Optical Hydrogen Peroxide Microsensors - Enabling H2O2 Profiling and Quantitative Biomedical Analysis"
7:50 pm - 8:00 pmDiscussion
8:00 pm - 8:20 pmKondalarao Bankapalli (Indian Institute of Science, India)
"Hsp31, a ThiJ/DJ-1/PfpI Family Member Protein Plays an Indispensable Role in Oxidative Stress Resistance in Saccharomyces cerevisiae"
8:20 pm - 8:30 pmDiscussion
8:30 pm - 8:50 pmShubhi Srivastava (Indian Institute of Science, India)
"Novel Function of Hsp40 Class of Chaperone in Regulation of Mitochondrial Redox Homeostasis"
8:50 pm - 9:00 pmDiscussion
9:00 pm - 9:20 pmLaura Corrales-Diaz Pomatto (University of Southern California, USA)
"Restoration of the Adaptive Response of the 20S Proteasome in D. melanogaster During Aging"
9:20 pm - 9:30 pmDiscussion
Sunday
7:30 am - 8:30 amBreakfast
9:00 am - 11:00 amRedox Biology in Disease
Discussion Leaders: Michael Davies (University of Copenhagen, Denmark) and William Reid (University of Delaware, USA)
9:00 am - 9:20 amAlex Gauthier (St. John's University, USA)
"GAT107, a Novel Agonistic Positive Allosteric Modulator of a7 Nicotinic Acetylcholine Receptor Restores Hyperoxia-Compromised Macrophage Function"
9:20 am - 9:30 amDiscussion
9:30 am - 9:50 amJennifer Pearson (University of Colorado Denver, USA)
"Scavenging Reactive Aldehydes Attenuates Cognitive Dysfunction Associated with Epileptogenesis"
9:50 am - 10:00 amDiscussion
10:00 am - 10:20 amShireen Attaran (University of Pittsburgh, USA)
"Prdx1 Inhibits Breast Cancer Progression Through Inhibiting the Activated Phenotype of Mammary Stroma-Associated Fibroblasts"
10:20 am - 10:30 amDiscussion
10:30 am - 10:50 amDouglas Ganini da Silva (National Institute of Environmental Health Sciences, NIH, USA)
"Human Mitochondrial SOD2 Incorporated with Iron by Its Prooxidant Peroxidase Activity Induces Mitochondrial Dysfunction in Cells"
10:50 am - 11:00 amDiscussion
11:00 am - 12:30 pmPoster Session

Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pmLunch
1:30 pm - 2:30 pmMentorship Component: Career Development
Discussion Leaders: Douglas Thomas (University of Illinois at Chicago, USA) and Sarah Stoecker (German Cancer Research Center (DKFZ), Germany)
1:30 pm - 2:15 pmChristine Winterbourn (University of Otago Christchurch, New Zealand)
"The Evolution of Free Radical Biology"
2:15 pm - 2:30 pmDiscussion
2:30 pm - 3:00 pmEvaluation Period
Fill in GRS Evaluation Forms
3:00 pmSeminar Concludes
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