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Single Molecule Approaches to Biology (GRS)
Gordon Research Seminar

Single-Molecule Microscopy: Life at a Higher Resolution

Dates

July 2-3, 2016

Location

The Chinese University of Hong Kong
Hong Kong, China

Organizers

Chair:
Kathy R. Chaurasiya

Hong Kong Advisory Board:
Tony F. Chan, Kathryn Song Eng Cheah, Fanny M.C. Cheung, Arthur B. Ellis, Barry Halliwell, Nancy Ip, Jian Lu, Peter Mathieson, Alfonso Ngan, Paul Tam, Benjamin Wah, Henry Wong, Vivian Wing-Wah Yam, Kenneth Young & Albert Cheung-Hoi Yu More Information

Meeting Description

This two-day Gordon Research Seminar on Single Molecule Approaches to Biology is an opportunity for junior scientists such as graduate students and post-docs to share their latest unpublished work and discuss emerging single molecule methods. Single molecule approaches have revolutionized the current understanding of important biological problems, and this conference is focused on facilitating the exchange of knowledge among young researchers in an inquisitive and stimulating environment. Topics will include fluorescence spectroscopy, force spectroscopy, and live cell imaging at the single molecule level.

Related Meeting

This GRS was held in conjunction with the "Single Molecule Approaches to Biology" Gordon Research Conference (GRC). Refer to the associated GRC program page for more information.

Contributors

Final Meeting Program

Saturday
2:00 pm - 5:00 pmArrival and Check-in
3:30 pm - 3:45 pmIntroductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair
3:45 pm - 4:30 pmKeynote Session: A Single-Molecule View on Intracellular Transport in Living C. elegans
Discussion Leader: Kathy Chaurasiya (Imperial College London, United Kingdom)
3:45 pm - 4:15 pmErwin Peterman (Vrije Universiteit Amsterdam, The Netherlands)
"A Single-Molecule View on Intracellular Transport in Living C. elegans"
4:15 pm - 4:30 pmDiscussion
4:30 pm - 6:00 pmPoster Session
6:00 pmDinner
7:30 pm - 9:30 pmSingle Molecule Fluorescence
Discussion Leader: Erik Holmstrom (University of Zurich, Switzerland)
7:30 pm - 7:50 pmHannah Tuson (University of Michigan, USA)
"Single-Molecule Fluorescence Microscopy Sheds Light on Protein Complex Formation in a Starch-Digesting Human Microbiome Bacterium"
7:50 pm - 8:00 pmDiscussion
8:00 pm - 8:20 pmKeisuke Fujita (RIKEN, Japan)
"Transcriptional Bursting Intrinsically Caused by Interplay Between RNAP Polymerases"
8:20 pm - 8:30 pmDiscussion
8:30 pm - 8:50 pmXiaoyu Shi (University of California, San Francisco, USA)
"Multicolor Super-Resolution Imaging and Correlation Analysis Reveal 3D Structure of Ciliary Transition Zone"
8:50 pm - 9:00 pmDiscussion
9:00 pm - 9:20 pmLucien Weiss (Stanford University, USA)
"Unraveling the Hedgehog Signaling Pathway by Single Molecule Tracking"
9:20 pm - 9:30 pmDiscussion
Sunday
7:30 am - 8:30 amBreakfast
9:00 am - 11:00 amSingle Molecule Force Spectroscopy
Discussion Leader: Lisa Alexander (University of California, Berkeley, USA)
9:00 am - 9:20 amSara Tafoya (University of California, Berkeley, USA)
"Molecular Mechanism for Mechanical and Catalytic Inter-Subunit Coordination of a Ring-Shaped Viral Packaging Machine"
9:20 am - 9:30 amDiscussion
9:30 am - 9:50 amDevin Edwards (JILA, University of Colorado Boulder, USA)
"Probing Protein Folding with 1-Microsecond Temporal Resolution on a Commercial AFM"
9:50 am - 10:00 amDiscussion
10:00 am - 10:20 amJorine Eeftens (Delft University of Technology, The Netherlands)
"Single-Molecule Experiments to Resolve Structural and Mechanical Properties of Condensin"
10:20 am - 10:30 amDiscussion
10:30 am - 10:50 amLukas Milles (Ludwig Maximilian University of Munich, Germany)
"Comparing Mechanical Stability of Arbitrary Receptor-Ligand Complexes with a Single Force Probe"
10:50 am - 11:00 amDiscussion
11:00 am - 12:30 pmPoster Session

Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pmLunch
1:30 pm - 2:30 pmMentorship Component: Career Panel
Discussion Leader: Sara Tafoya (University of California, Berkeley, USA)
1:30 pm - 2:30 pmPanel Discussion
"Careers in Single Molecule Biophysics"
  • Erwin Peterman (Vrije Universiteit Amsterdam, The Netherlands)
  • Antoine Van Oijen (University of Wollongong, Australia)
  • Houra Merrikh (University of Washington, USA)
2:30 pm - 3:00 pmEvaluation Period
Fill in GRS Evaluation Forms
3:00 pmSeminar Concludes
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