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Basal Ganglia
Gordon Research Conference

Mechanisms Underlying Basal Ganglia Function and Dysfunction

Dates

March 11-16, 2018

Location

Four Points Sheraton / Holiday Inn Express
Ventura, CA Site Information

Organizers

Chair:
Mark Bevan

Vice Chairs:
Rui Costa & Margaret E. Rice

Application Deadline

Applications for this meeting must be submitted by February 11, 2018. Please apply early, as some meetings become oversubscribed (full) before this deadline. If the meeting is oversubscribed, it will be stated here. Note: Applications for oversubscribed meetings will only be considered by the Conference Chair if more seats become available due to cancellations.

Meeting Description

The basal ganglia are a richly interconnected group of subcortical brain nuclei that are critical for the motivation, selection, initiation and execution of actions. Consistent with these roles, dysfunction of the basal ganglia is linked to a range of debilitating disorders including Parkinson's disease, Huntington's disease, dystonia, addiction, obsessive compulsive disorder and Tourette's syndrome. With recent technical advances in our ability to observe and perturb molecules, neurons, and astrocytes, together with increasingly powerful molecular and genetic interrogation approaches, our views of basal ganglia circuits and their contribution to brain function and dysfunction are evolving rapidly. Furthermore, the unprecedented streams of data arising from these approaches are revealing properties and mechanisms that could be targeted for therapeutic benefit. This conference will bring together basic, clinical and translational scientists with diverse perspectives and technical expertise from across the world to discuss their latest discoveries and to promote community interaction and collaboration. Besides addressing long-standing basal ganglia research questions, the 2018 meeting will incorporate subjects that have previously received little attention including basal ganglia development, interactions of the basal ganglia with the wider motor system, the striosome/patch compartment, involvement of the basal ganglia in neuropsychiatric disorders, and basal ganglia connectomics.

Related Meeting

This GRC will be held in conjunction with the "Basal Ganglia" Gordon Research Seminar (GRS). Those interested in attending both meetings must submit an application for the GRS in addition to an application for the GRC. Refer to the associated GRS program page for more information.

Contributors

Gordon Research Conferences

Session Titles

The Conference will consist of nine sessions, on the topics listed below. The Conference Chair is currently developing their preliminary program, which will include the names of the invited speakers and discussion leaders for each of these sessions. The preliminary program will be available by July 1, 2017. Please check back for updates.

  • Action Selection and Suppression by the Basal Ganglia
  • Intrinsic Properties and Synaptic Patterning of Midbrain Dopamine Neurons
  • Dopaminergic and Cholinergic Modulation of the Basal Ganglia
  • Processing of Cortical Information by the Basal Ganglia
  • Who's Driving? The Thalamus and Basal Ganglia
  • Basal Ganglia Development and the STN-GPe Network
  • Interactions of the Basal Ganglia with the Wider Motor System
  • Mechanisms Underlying Basal Ganglia – Associated Disease
  • Therapeutic Opportunities from Manipulation of Basal Ganglia Circuitry
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