Gordon Research Conferences
Meeting Details
Search:
  GO

Sleep Regulation & Function
Gordon Research Conference

Functions of Sleep in Body and Brain

Dates

March 13-18, 2016

Location

Hotel Galvez
Galveston, TX

Organizers

Chair:
Craig Heller

Vice Chair:
Chiara Cirelli

Meeting Description

Sleep regulation and function is arguably one of the biggest unanswered questions in biology. It is common to begin didactic lectures on sleep with the statement "we spend one third of our lives sleeping and we don’t know why or how". Enormous progress has been made in recent years on the "how" problem. Beginning with the identification of different brain regions involved in controlling wake, sleep, and sleep states, there has been rapid progress is studying their neurochemistry, patterns of gene expression, electrophysiological signatures, and interactions. Much of this progress constituted themes of the first GRC on "Sleep Regulation and Function: Emerging Themes and Paradigm Shifts" held in 2014. We will continue to be concerned with recent advances on the "how" questions with sessions on epigenetics of sleep and new circuits involved in sleep regulation, but will delve deeper into the "why" questions – the function(s) of sleep. Whereas the prevailing view had been, as expressed by Dr. Alan Hobson, "Sleep is of the brain, by the brain, and for the brain". We are increasingly discovering links between sleep and non-brain functions that have huge impacts on health. In this GRC we will explore the role of sleep in the immune system and also the role of sleep in pain and fatigue mechanisms. We’ll also focus on an entirely new consideration, sleep and the microbiome. Brain functions of sleep are still leading hypotheses and areas of exciting investigation that will be covered, and the most exciting at present is the involvement of sleep in the neurophysiology of memory consolidation which will be the subject of our keynote and also one of our sessions. The field of sleep is advancing and broadening rapidly, and the significance of this meeting is that we will bring together leaders in these various areas with the intent of developing a more integrative view of sleep that will help guide future work. A main goal of this meeting will be to discover and discuss where opportunities exist for significant advances in basic sleep research.

Related Meeting

This GRC was held in conjunction with the "Sleep Regulation & Function" Gordon Research Seminar (GRS). Refer to the associated GRS program page for more information.

Contributors

Final Meeting Program

Sunday
4:00 pm - 8:00 pmArrival and Check-in
6:00 pmDinner
7:30 pm - 7:40 pmWelcome / Introductory Comments by GRC Site Staff
7:40 pm - 9:30 pmKeynote Session: Rhythms of the Brain
Discussion Leader: Ronald Szymusiak (University of California, Los Angeles, USA)
7:40 pm - 8:00 pmOpening Remarks
8:00 pm - 9:00 pmGyorgy Buzsaki (New York University, USA)
"Rhythms of the Brain"
9:00 pm - 9:30 pmDiscussion
Monday
7:30 am - 8:30 amBreakfast
8:30 amGroup Photo
9:00 am - 12:30 pmSleep Disruption, Pain, and Fatigue
Discussion Leader: Ralph Lydic (University of Tennessee, USA)
9:00 am - 9:30 amMonika Haack (Harvard University / Beth Israel Deaconess Medical Center, USA)
"Restricting Sleep During the Week and Catching up on Weekends: Effects on Pain and Inflammation"
9:30 am - 9:45 amDiscussion
9:45 am - 10:15 amMark Opp (University of Washington, USA)
"Sleep Disruption Contributes to Chronic Pain"
10:15 am - 10:30 amDiscussion
10:30 am - 11:00 amCoffee Break
11:00 am - 11:30 amMichael Smith (Johns Hopkins University, USA)
"Disrupted Sleep and Pain Amplification"
11:30 am - 11:45 amDiscussion
11:45 am - 12:15 pmMiranda Lim (VA Portland Health Care System / Oregon Health and Science University, USA)
"The Impact of Sleep Disruption on Social Behavior"
12:15 pm - 12:30 pmDiscussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
3:00 pm - 4:00 pmPower Hour
The GRC Power Hour is an optional informal gathering open to all meeting participants. It is designed to help address the challenges women face in science and support the professional growth of women in our communities by providing an open forum for discussion and mentoring.
Organizers: Mary Carskadon (Alpert Medical School, Brown University, USA) and Gina Poe (University of Michigan, USA)
4:00 pm - 6:00 pmPoster Session
6:00 pmDinner
7:30 pm - 9:30 pmSleep and Epigenetics
Discussion Leader: Ted Abel (University of Pennsylvania, USA)
7:30 pm - 8:00 pmMary Carskadon (Alpert Medical School, Brown University, USA)
"Naturalistic Study of Methylomic Responses to Short or Long Sleep in Humans -- Preliminary Findings and Perspective of a Tyro"
8:00 pm - 8:10 pmDiscussion
8:10 pm - 8:40 pmValerie Mongrain (Université de Montréal, Canada)
"DNA Methylation, Enhancers and Sleep Deprivation in the Mouse Cerebral Cortex"
8:40 pm - 8:50 pmDiscussion
8:50 pm - 9:20 pmErin Hanlon (University of Chicago, USA)
"Circadian Rhythms in the Endocannabinoid System and Alterations Following Sleep Restriction"
9:20 pm - 9:30 pmDiscussion
Tuesday
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmNeurophysiology of Memory Consolidation During Sleep
Discussion Leader: Gina Poe (University of Michigan, USA)
9:00 am - 9:40 amJan Born (University of Tuebingen, Germany)
"Sleep for Preserving and Transforming Episodic Memory"
9:40 am - 10:00 amDiscussion
10:00 am - 10:30 amCoffee Break
10:30 am - 11:10 amKarim Benchanane (Centre National de la Recherche Scientifique (CNRS), France)
"Altering and Creating Memories During Sleep"
11:10 am - 11:30 amDiscussion
11:30 am - 12:10 pmMatthew Wilson (Massachusetts Institute of Technology, USA)
"Communication Between the Hippocampus and Cortex During Sleep"
12:10 pm - 12:30 pmDiscussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session
6:00 pmDinner
7:30 pm - 9:30 pmSleep Aging and Neurodegeneration
Discussion Leader: David Dinges (University of Pennsylvania, USA)
7:30 pm - 8:00 pmDavid Holtzman (Washington University in St. Louis, USA)
"Sleep Quality and Preclinical AD"
8:00 pm - 8:10 pmDiscussion
8:10 pm - 8:40 pmClifford Saper (Harvard Medical School, USA)
"VLPO. Sleep Fragmentation, and AD"
8:40 pm - 8:50 pmDiscussion
8:50 pm - 9:20 pmErik Musiek (Washington University School of Medicine in St. Louis, USA)
"Circadian Disruption and Neurodegeneration"
9:20 pm - 9:30 pmDiscussion
Wednesday
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmNew Circuits that Regulate Sleep
Discussion Leader: Barbara Jones (McGill University, Canada)
9:00 am - 9:30 amChristelle Anaclet (Harvard University / Beth Israel Deaconess Medical Center, USA)
"The Slow-Wave-Sleep Promoting Parafacial Zone"
9:30 am - 9:45 amDiscussion
9:45 am - 10:15 amPierre-Herve Luppi (University of Lyon / UMR 5292 CNRS / U1028 INSERM, France)
"New Findings on the Cortical and Subcortical Pathways Activated During Paradoxical (REM) Sleep"
10:15 am - 10:30 amDiscussion
10:30 am - 11:00 amCoffee Break
11:00 am - 11:30 amLior Appelbaum (Bar-Ilan University, Israel)
"Live Imaging of Neuronal Activity and Structural Synaptic Plasticity During Day and Night"
11:30 am - 11:45 amDiscussion
11:45 am - 12:15 pmJeffrey Donlea (University of Oxford, United Kingdom)
"Sleep Control by an Excitability Switch in Drosophila dFB Neurons"
12:15 pm - 12:30 pmDiscussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session
6:00 pmDinner
7:30 pm - 9:30 pmThe Role of Sleep in Peripheral Systems
Discussion Leader: Janet Mullington (Beth Israel Deaconess Medical Center, Harvard Medical School, USA)
7:30 pm - 8:00 pmCarol Everson (The Medical College of Wisconsin, USA)
"Sleep Restriction: Abundant Insidious Effects and Diverse Medical Implications"
8:00 pm - 8:10 pmDiscussion
8:10 pm - 8:40 pmFahed Hakim (Technion - Israel Institute of Technology, Israel)
"Sleep Apnea Awakens Cancer: The Immunological Perspective"
8:40 pm - 8:50 pmDiscussion
8:50 pm - 9:20 pmAsya Rolls (Technion - Israel Institute of Technology, Israel)
"Sleep Effects on Immune System Development"
9:20 pm - 9:30 pmDiscussion
Thursday
7:30 am - 8:30 amBreakfast
8:30 am - 9:00 amBusiness Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
9:00 am - 12:30 pmSleep as a Window to Study Consciousness
Discussion Leader: Giulio Tononi (University of Wisconsin, USA)
9:00 am - 9:30 amYukiyasu Kamitani (Kyoto University, Japan)
"Decoding Dream Contents from Human Brain Activity"
9:30 am - 9:45 amDiscussion
9:45 am - 10:15 amFrancesca Siclari (University Hospital Lausanne (CHUV), Switzerland)
"The Neural Correlates of Consciousness in Sleep: A High-Density EEG Investigation"
10:15 am - 10:30 amDiscussion
10:30 am - 11:00 amCoffee Break
11:00 am - 11:30 amUrsala Voss (Frankfurt University, Germany)
"Lucid Dreaming"
11:30 am - 11:45 amDiscussion
11:45 am - 12:15 pmEnzo Tagliazucchi (Netherlands Institute for Neuroscience, The Netherlands)
"Sleep, Complexity, and Consciousness"
12:15 pm - 12:30 pmDiscussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session
6:00 pmDinner
7:30 pm - 9:30 pmSleep and the Microbiome
Discussion Leader: Derk-Jan Dijk (University of Surrey, United Kingdom)
7:30 pm - 8:00 pmEran Elinav (Weizmann Institute of Science, Israel)
"Microbiome Time"
8:00 pm - 8:10 pmDiscussion
8:10 pm - 8:40 pmMonika Fleshner (University of Colorado Boulder, USA)
"Early Life Prebiotic Diet, Stress and Sleep"
8:40 pm - 8:50 pmDiscussion
8:50 pm - 9:20 pmKenneth Wright (University of Colorado Boulder, USA)
"Insufficient Sleep and the Microbiome"
9:20 pm - 9:30 pmDiscussion
Friday
7:30 am - 8:30 amBreakfast
9:00 amDeparture

Research reported in this publication was supported by the National Institute Of Neurological Disorders And Stroke of the National Institutes of Health under Award Number R13NS095356. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.
© 2017 Gordon Research Conferences Search | Contact | Terms of Use | Privacy Policy | Follow us: Facebook Twitter