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Enzymes, Coenzymes & Metabolic Pathways (GRS)
Gordon Research Seminar

New Discoveries, Mechanisms and Technologies: Advancing the Frontiers of Enzymology

Dates

July 15-16, 2017

Location

Waterville Valley
Waterville Valley, NH Site Information

Organizers

Chair:
Crystal Smitherman Rosenberg

Application Deadline

The application deadline for this meeting was June 17, 2017. You may still submit an application, which may be considered by the conference chair if there is still room available.

Meeting Description

Overview

The Gordon Research Seminar on Enzymes, Coenzymes and Metabolic Pathways is a unique forum for graduate students, post-docs, and other scientists with comparable levels of experience and education to present and exchange new data and cutting edge ideas.

The 2017 GRS will highlight the latest advances, innovations and new discoveries in enzymology from the fundamentals of determining enzyme function to complex enzyme mechanisms and their roles in cancer and disease. This meeting will also emphasize career development by including a panel of senior and junior leaders from academia, industry, government and beyond, as well as providing multiple opportunities to network in a casual, stimulating environment.

Application Instructions

The meeting will feature approximately 10 talks and 2 poster sessions. All attendees are expected to actively participate in the GRS either by giving an oral presentation or presenting a poster. Therefore, all applications must include an abstract.

The Chairs will select speakers from abstracts submitted by April 15, 2017. Those applicants who are not chosen for talks and those who apply after the deadline to be considered for an oral presentation will be expected to present a poster. In order to participate, you must submit an application by the date indicated in the Application Deadline section above.

Related Meeting

This GRS will be held in conjunction with the "Enzymes, Coenzymes & Metabolic Pathways" Gordon Research Conference (GRC). Those interested in attending both meetings must submit an application for the GRC in addition to an application for the GRS. Refer to the associated GRC program page for more information.

Contributors

Meeting Program

Saturday
2:00 pm - 5:00 pmArrival and Check-in
3:30 pm - 3:45 pmIntroductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair
3:45 pm - 4:30 pmKeynote Session: Phosphonate Biosynthesis
Discussion Leader: Crystal Smitherman Rosenberg (Aalto Scientific, Ltd., USA)
3:45 pm - 4:15 pmWilfred van der Donk (Howard Hughes Medical Institute / University of Illinois at Urbana-Champaign, USA)
"Phosphonate Biosynthesis: A Treasure Trove for Novel Enzymology"
4:15 pm - 4:30 pmDiscussion
4:30 pm - 6:00 pmPoster Session
6:00 pmDinner
7:30 pm - 9:30 pmAdvances in Fundamentals of Enzymology
Discussion Leader: Emilia Strandback (Graz University of Technology, Austria)
7:30 pm - 7:50 pmEric Koehn (University of California, Berkeley, USA)
"Characterization of PqqB: A Protein of Unknown Function Within the Pyrroloquinoline Quinone (PQQ) Biosynthetic Pathway"
7:50 pm - 8:00 pmDiscussion
8:00 pm - 8:20 pmJacquelyn Blake-Hedges (University of California, Berkeley, USA)
"Investigating the Regiospecificity of an Unusual Bacterial Acyl-CoA Dehydrogenase"
8:20 pm - 8:30 pmDiscussion
8:30 pm - 8:50 pmJohn Janetzko (Harvard Medical School, USA)
"It's a Trap! Asp/Glu Carboxylate Glycosylation of O-GlcNAc Transferase Triggers Peptide Backbone Reactions"
8:50 pm - 9:00 pmDiscussion
9:00 pm - 9:20 pmErin McCarthy (Pennsylvania State University, USA)
"Destruction and Reformation of an Iron-Sulfur Cluster During Catalysis by Lipoyl Synthase"
9:20 pm - 9:30 pmDiscussion
Sunday
7:30 am - 8:30 amBreakfast
9:00 am - 11:00 amInnovations and Applications of Enzymology and Metabolic Pathways
Discussion Leader: Matteo Planchestainer (University of Nottingham, United Kingdom)
9:00 am - 9:20 amMaureen Hill (University of Massachusetts Amherst, USA)
"Engineered Caspases with Altered Specificities Enable Identification of Exosites"
9:20 am - 9:30 amDiscussion
9:30 am - 9:50 amVanessa Chaplin (University of Massachusetts Amherst, USA)
"Engineering Alternate Radical Rebound Chemistry in Factor Inhibiting HIF (FIH)"
9:50 am - 10:00 amDiscussion
10:00 am - 10:20 amJames Vranish (U.S. Naval Research Laboratory, USA)
"Enhanced Catalysis of Glycolytic Pathways by Co-Localization of Enzymes on Nanoparticle Surfaces"
10:20 am - 10:30 amDiscussion
10:30 am - 10:50 amCathleen Zeymer (ETH Zurich, Switzerland)
"The Enzyme Mechanism of a De Novo Designed and Evolved Aldolase"
10:50 am - 11:00 amDiscussion
11:00 am - 12:30 pmPoster Session

Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pmLunch
1:30 pm - 2:30 pmMentorship Component: Broadening Horizons in the Scientific Career Landscape
This session serves as the career development discussion panel of the conference. The panelists include investigators in academia and industry, as well as experts in non-traditional careers. They will discuss different career paths, offer advice on career development, and answer questions from conference attendees.
Discussion Leader: Tatiana Mishanina (University of Wisconsin-Madison, USA)
1:30 pm - 2:30 pmPanel Discussion
"Broadening Horizons in the Scientific Career Landscape"
  • Kay Ahn (Janssen Research & Development, USA)
  • Holly Ellis (Auburn University, USA)
  • Stefan Gross (Agios Pharmaceuticals, USA)
  • Nicole Neuman (Trends in Biochemical Sciences, Cell Press, USA)
  • Wilfred van der Donk (Howard Hughes Medical Institute / University of Illinois at Urbana-Champaign, USA)
2:30 pm - 3:00 pmEvaluation Period
Fill in GRS Evaluation Forms
3:00 pmSeminar Concludes
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