Gordon Research Conferences
Meeting Details

Preclinical Form and Formulation for Drug Discovery (GRS)
Gordon Research Seminar

New Insights and Advanced Approaches in Preclinical Drug Development


June 3-4, 2017


Stoweflake Conference Center
Stowe, VT


Rui Fang & Yinshan Chen

Meeting Description

The Gordon Research Seminar on Preclinical Form and Formulation for Drug Discovery is a unique forum for graduate students, post-docs, and other scientists with comparable levels of experience and education to present and exchange new data and cutting edge ideas.

The focus of this meeting is on recent progress in understanding and new strategies in preclinical drug development including conventional formulations as well as novel therapies. Discussion topics include, but are not limited to, new approaches in enhancing solubility of poorly-soluble drugs, protein stability, targeted drug delivery, and new analytical methodologies. Additionally, experts in academia and industry will share their experience and provide a general perspective on the future of pharmaceutical research.

Related Meeting

This GRS was held in conjunction with the "Preclinical Form and Formulation for Drug Discovery" Gordon Research Conference (GRC). Refer to the associated GRC program page for more information.


Meeting Program

2:00 pm - 5:00 pmArrival and Check-in
3:30 pm - 3:45 pmIntroductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair
3:45 pm - 4:30 pmKeynote Session: Preclinical Form and Formulation for Drug Discovery
Discussion Leader: Narayan Variankaval (Merck Research Laboratories, USA)
3:45 pm - 4:20 pmNicholas Warne (Pfizer, USA)
"Biotechnology Dosage Form Development for the Rapidly Evolving Healthcare Environment"
4:20 pm - 4:30 pmDiscussion
4:30 pm - 6:00 pmPoster Session
6:00 pmDinner
7:30 pm - 9:30 pmParenteral Formulations: Characterization and Stability
Discussion Leaders: Adora Padilla (GSK Vaccines, USA) and Adrian Defante (National Institute of Standards and Technology, USA)
7:30 pm - 7:50 pmAshley Lay (University of Kentucky, USA)
"Solid-State NMR Spectroscopy: A Versatile Tool for Characterizing Lyophilized Protein Formulations"
7:50 pm - 8:00 pmDiscussion
8:00 pm - 8:20 pmCarly Chisholm (University of Colorado Boulder, USA)
"Stability of Therapeutic Protein Formulations in Novel Cyclic Olefin Polymer Vials and Syringes Containing Silica-Coated Surfaces"
8:20 pm - 8:30 pmDiscussion
8:30 pm - 8:50 pmShreya Kulkarni (University of Connecticut, USA)
"Why Does Crystallization of Mannitol Lower the Reconstitution Times of Freeze-Dried Highly Concentrated Protein Formulations?"
8:50 pm - 9:00 pmDiscussion
9:00 pm - 9:20 pmRikhav Gala (Mercer University, USA)
"Formulation and Preclinical Evaluation of a Novel Buccal and Transdermal Measles Vaccine"
9:20 pm - 9:30 pmDiscussion
7:30 am - 8:30 amBreakfast
9:00 am - 11:00 amOral Dosage Forms: Drug Delivery and Formulation
Discussion Leaders: Sachin Lohani (Janssen Pharmaceuticals, USA) and Alpana Thorat (Purdue University, USA)
9:00 am - 9:20 amPeng Yu (The University of Iowa, USA)
"Thermodynamic Understanding of Enthalpy-Driven Adsorption Phenomena: Phenobarbital and Activated Carbons as the Model System"
9:20 am - 9:30 amDiscussion
9:30 am - 9:50 amSampada Koranne (University of Minnesota, USA)
"Investigation of Spatial Heterogeneity of Salt Disproportionation in Tablets by Synchrotron X-Ray Diffractometry"
9:50 am - 10:00 amDiscussion
10:00 am - 10:20 amJulie Calahan (University of Kentucky, USA)
"Correlating the Effect of Physicochemical Properties of Magnesium Stearate with Indomethacin Tablet Dissolution"
10:20 am - 10:30 amDiscussion
10:30 am - 10:50 amBart Hens (University of Michigan, USA)
"Formulation Predictive Dissolution (fPD) for Oral Drug Products"
10:50 am - 11:00 amDiscussion
11:00 am - 12:30 pmPoster Session

Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pmLunch
1:30 pm - 2:30 pmMentorship Component: Career Panel
Discussion Leader: Yongchao Su (Merck Research Laboratories, USA)
1:30 pm - 2:30 pmPanel Discussion
"Careers in Pharmaceutical Sciences"
  • Annette Bak (AstraZeneca, Sweden)
  • Eric Munson (University of Kentucky, USA)
  • Elizabeth Topp (Purdue University, USA)
2:30 pm - 3:00 pmEvaluation Period
Fill in GRS Evaluation Forms
3:00 pmSeminar Concludes

Research reported in this publication was supported by the National Center For Advancing Translational Sciences of the National Institutes of Health under Award Number 1R13TR001914-01A1. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.
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