Hormone-Dependent Cancers (GRS)

Gordon Research Seminar

Bridging Research in Hormone Response and Resistance in Cancer

August 15 - 16, 2015
Chairs and
Grand Summit Hotel at Sunday River
97 Summit Road
Newry, Maine, United States
 Venue and Travel Information

Conference Description

The Gordon Research Seminar on Hormone-Dependent Cancers is a unique forum for graduate students, post-docs, and other scientists with comparable levels of experience and education to present and exchange new data and cutting edge ideas.

The focus of this meeting is to highlight parallels in basic and translational research in hormone action across breast, prostate, and other cancer types. The goals of this seminar are to a) provide a setting for fellow trainees to present their projects and learn about their peers' research with the aim of fostering future interaction and collaboration, b) to promote career dialogue via a keynote presentation and panel discussion led by a diverse group of senior professionals, and c) to facilitate networking for trainees with senior scientists and mentors.

Related Meeting

This GRS will be held in conjunction with the "Hormone-Dependent Cancers" Gordon Research Conference (GRC). Those interested in attending both meetings must submit an application for the GRC in addition to an application for the GRS. Refer to the associated GRC program page for more information.

Conference Program

Saturday
2:00 pm - 5:00 pmArrival and Check-in
3:30 pm - 3:45 pmIntroductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair
3:45 pm - 4:30 pmKeynote Session: Career Development for Early Career Researchers
Discussion Leader: Matthew Sikora (University of Pittsburgh, USA)
3:45 pm - 4:20 pmRobert Clarke (Georgetown University, USA)
"Career Development for Early Career Researchers"
4:20 pm - 4:30 pmDiscussion
4:30 pm - 6:00 pmPoster Session
6:00 pmDinner
7:30 pm - 9:30 pmTumor Biology of Hormone-Dependent Cancers
Discussion Leaders: Daniel Frigo (University of Houston, USA) and Ayesha Khan (University of Houston, USA)
7:30 pm - 7:45 pmRajdeep Das (Dame Roma Mitchell Cancer Research Laboratories, Australia)
"MicroRNA-194 Is Elevated in Advanced Prostate Cancer and Enhances Metastatic Phenotypes by Targeting SOCS2"
7:45 pm - 7:50 pmDiscussion
7:50 pm - 8:05 pmAlicia Blessing (University of Houston, USA)
"Identification of a Novel Coregulator, SH3YL1, that Interacts with the Androgen Receptor N-Terminus"
8:05 pm - 8:10 pmDiscussion
8:10 pm - 8:25 pmOscar Vidal (National Cancer Institute, NIH, USA)
"A Novel Tumor Suppressive Role for the Dopamine Receptor DRD1 in Lung Cancer"
8:25 pm - 8:30 pmDiscussion
8:30 pm - 8:45 pmValerie Barton (University of Colorado Denver Anschutz Medical Campus, USA)
"Androgen Receptor (AR) Supports a Tumor Initiating Population in AR+ Triple-Negative Breast Cancer"
8:45 pm - 8:50 pmDiscussion
8:50 pm - 9:05 pmRyan Bourgo (University of Chicago, USA)
"Capture of Associated Targets on Chromatin (CATCH) Identifies the Presence of eRNAs at Transcriptional Enhancers"
9:05 pm - 9:10 pmDiscussion
9:10 pm - 9:25 pmLaura Baker (Garvan Institute of Medical Research, Australia)
"Single-Cell Analysis of Breast Cancer Molecular Subtypes Reveals Clinically Relevant Heterogeneity"
9:25 pm - 9:30 pmDiscussion
Sunday
7:30 am - 8:30 amBreakfast
9:00 am - 11:00 amEndocrine Therapy and Novel Targets
Discussion Leaders: Naomi Laing (AstraZeneca R&D Boston, USA) and Matthew Schiewer (Thomas Jefferson University, USA)
9:00 am - 9:15 amDaniel Tamae (University of Pennsylvania, USA)
"The DHEA-S Depot May Feed Intratumoral Androgen Biosynthesis via AKR1C3 and Drive Resistance to P450c17 Inhibitors in Castration-Resistant Prostate Cancer"
9:15 am - 9:20 amDiscussion
9:20 am - 9:35 amYinghui Zhang (Leiden University, The Netherlands)
"PAK2/PIX Survival Components Play a Regulatory Role in IGF-1 Receptor-Mediated Antiestrogen Resistance"
9:35 am - 9:40 amDiscussion
9:40 am - 9:55 amCourtney Andersen (University of Pittsburgh, USA)
"Identifying Predictive Biomarkers of Endocrine Response in High-Grade Serous Ovarian Cancer"
9:55 am - 10:00 amDiscussion
10:00 am - 10:15 amBrendon Ladd (AstraZeneca, USA)
"Effective Combination Therapies in Endocrine Resistant Breast Cancers Harboring an ER Mutation"
10:15 am - 10:20 amDiscussion
10:20 am - 10:35 amFlavia Marialucia Fioretti (Imperial College London, United Kingdom)
"Optimization of an Engineered Microrepressor for the Treatment of Castration-Resistant Prostate Cancer"
10:35 am - 10:40 amDiscussion
10:40 am - 10:55 amSachi Horibata (Cornell University, USA)
"Role of Peptidylarginine Deiminase Enzyme 2 in Breast Cancer Progression"
10:55 am - 11:00 amDiscussion
11:00 am - 12:30 pmPoster Session

Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pmLunch
1:30 pm - 2:30 pmMentorship Component: Career Development Panel Discussion
Discussion Leader: Renée de Leeuw (Thomas Jefferson University, USA)
1:30 pm - 1:35 pmDaniel Frigo (University of Houston, USA)
"Academic Tenure-Track Faculty"
1:35 pm - 1:45 pmDiscussion
1:45 pm - 1:50 pmRemy Brim (Legislative Assistant, USA)
"Federal Government and Science Policy"
1:50 pm - 2:00 pmDiscussion
2:00 pm - 2:05 pmDevin Rosenthal (Rho Inc., USA)
"Contract Research Organizations"
2:05 pm - 2:15 pmDiscussion
2:15 pm - 2:20 pmNaomi Laing (AstraZeneca R&D Boston, USA)
"Pharmaceutical Industry"
2:20 pm - 2:30 pmDiscussion
2:30 pm - 3:00 pmEvaluation Period
Fill in GRS Evaluation Forms
3:00 pmSeminar Concludes

Contributors

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