| Saturday |
| 2:00 pm - 5:00 pm | Arrival and Check-in |
| 3:30 pm - 3:45 pm | Introductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair |
| 3:45 pm - 4:30 pm | Keynote Session: Curiosity, Questions, and Discovery |
| Discussion Leaders: Somaira Nowsheen (Mayo Clinic, USA) and Yinbo Zhang (University of Nebraska Medical Center, USA) |
| 3:45 pm - 4:15 pm | Johannes Walter (Harvard Medical School, USA)
"At the Intersection of Vertebrate DNA Replication and Repair" |
| 4:15 pm - 4:30 pm | Discussion |
| 4:30 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Diverse Strategies for Investigating Fidelity of DNA Repair / Regulation of the Cellular Response to DNA Damage |
| Discussion Leaders: Melike Caglayan (National Institute of Environmental Health Sciences, NIH, USA) and Muthiah Bose (University of Oulu, Finland) |
| 7:30 pm - 7:45 pm | Eric Josephs (Duke University, USA)
"Structure and Mechanics of Repair Complexes During Methyl-Directed DNA Mismatch Repair" |
| 7:45 pm - 7:55 pm | Discussion |
| 7:55 pm - 8:10 pm | Nicole Williams (University of California, Riverside, USA)
"The Roles of DNA Polymerases Eta, Iota, Kappa and Zeta in the Bypass of O2- and O4-Alkylthymidine Lesions In Vitro and in Human Cells" |
| 8:10 pm - 8:20 pm | Discussion |
| 8:20 pm - 8:35 pm | Taty Taty Gemael Cedrick (LBCMCP, Université Paul Sabatier, France)
"Role of Chromatin Remodeling Enzymes in the Repair of DNA Double Strand Breaks and Genetic Instability" |
| 8:35 pm - 8:45 pm | Discussion |
| 8:45 pm - 9:00 pm | Katherine Choe (Pennsylvania State University College of Medicine, USA)
"HUWE1 Is a Novel PCNA-Interacting Protein that Promotes the Repair of Broken Replication Forks" |
| 9:00 pm - 9:10 pm | Discussion |
| 9:10 pm - 9:25 pm | Judit Jimenez Sainz (Yale School of Medicine, USA)
"The Two BRC Repeat Modules in BRCA2 Mediate Distinct Binding Modes for RAD51 and Differential Sensitivity to DNA Damage" |
| 9:25 pm - 9:30 pm | Discussion |
| Sunday |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 11:00 am | RNA-DNA Interplay in Genome Instability /
Fragile and Repetitive DNA Sequences |
| Discussion Leaders: John Pryor (University of North Carolina, USA) and Katharina Bilotti (Brown University, USA) |
| 9:00 am - 9:15 am | Alessandra Brambati (Institute of Molecular Genetics (IGM), National Research Council, Italy)
"Mechanisms that Rescue Replication Forks Arrested by Transcription" |
| 9:15 am - 9:25 am | Discussion |
| 9:25 am - 9:40 am | Kate Reid-Bayliss (University of Washington, USA)
"Detection of RNA Mutations Due to Transcriptional Infidelity by Next-Generation Sequencing" |
| 9:40 am - 9:50 am | Discussion |
| 9:50 am - 10:05 am | Jinchuan Hu (University of North Carolina School of Medicine, USA)
"Mapping UV and Cisplatin Induced DNA Damage and Repair at Nucleotide Resolution in Human Cells" |
| 10:05 am - 10:15 am | Discussion |
| 10:15 am - 10:30 am | Ryan Barnes (Pennsylvania State University College of Medicine, USA)
"Human DNA Polymerase Eta Mitigates Replication Stress and Preserves Genome Stability by Replicating Common Fragile Sites" |
| 10:30 am - 10:40 am | Discussion |
| 10:40 am - 10:55 am | Xiaofeng Su (Tufts University, USA)
"Cytosine Deamination Mediates R-Loop Dependent CAG Repeat Fragility and Instability" |
| 10:55 am - 11:00 am | Discussion |
| 11:00 am - 12:30 pm | Poster Session |
| Coffee will be served in the poster area from 11:00 am - 11:30 am |
| 12:30 pm | Lunch |
| 1:30 pm - 2:30 pm | Mentorship Component: Strategies for Successful Funding |
| Discussion Leader: Alexander Neil (Tufts Unversity, USA) |
| 1:30 pm - 2:30 pm | Panel Discussion |
| "Strategies for Successful Funding" |
|
- Anna Malkova (University of Iowa, USA)
- Mitch McVey (Tufts University, USA)
- Wendy Lam (Franklin Templeton Investments, USA)
- Eric Olmon (Brown University, USA)
|
| 2:30 pm - 3:00 pm | Evaluation Period |
| Fill in GRS Evaluation Forms |
| 3:00 pm | Seminar Concludes |
