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Biology of Host-Parasite Interactions (GRS)
Gordon-Kenan Research Seminar

Molecular-Genetic Studies to Control Parasitic Diseases

Dates

June 11-12, 2016

Location

Salve Regina University
Newport, RI

Organizers

Chairs:
Alassane Mbengue & Eleanor Saunders

Meeting Description

The Gordon Research Seminar on the Biology of Host-Parasite Interactions is a unique forum for graduate students, post-docs, and other scientists with comparable levels of experience and education to present and exchange new data and cutting edge ideas.

The 2016 GRS on the Biology of Host-Parasite Interactions is focused on new molecular-genetic studies in parasitic diseases. The meeting will place special emphasis on cutting edge methodologies needed for molecular discovery and validation for new therapeutic strategies to control world-wide disease burdens of malaria, toxoplasmosis, trypanosomiasis, leishmaniasis, amoebiasis and worm infections. The program will feature a broad range of topics including (i) Host parasite interactions in parasitic diseases with emphasis on signaling pathways, (ii) Discovery and mechanism of drugs and molecular basis of resistance and (iii) Leading molecular tools to validate targets, as well as mechanisms of infection and disease. The aim of the meeting is to bring together young scientists with special emphasis on early career scientists including advanced graduate students from endemic areas to develop new knowledge platforms critical for future control and elimination research. This GRS will offer unique opportunity to young scientists to build scientific acumen and peer networks to sustain competitive, world-class research in a stimulating atmosphere at the Salve Regina University Campus, Newport. All talks will be selected from submitted abstracts based on their findings. Students, post-docs and early career scientists are strongly encouraged to apply to the GRC and GRS. Special efforts are being made to raise funds to provide individuals from endemic countries with support.

Related Meeting

This GRS was held in conjunction with the "Biology of Host-Parasite Interactions" Gordon Research Conference (GRC). Refer to the associated GRC program page for more information.

Contributors

Final Meeting Program

Saturday
2:00 pm - 5:00 pmArrival and Check-in
3:30 pm - 3:45 pmIntroductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair
3:45 pm - 4:30 pmKeynote Session: Host-Pathogen Interactions
Discussion Leader: Marcus Lee (Wellcome Trust Sanger Institute, United Kingdom)
3:45 pm - 4:15 pmKirk Deitsch (Weill Cornell Medical College, USA)
"Mechanisms of Gene Expression in Malaria Pathogenesis"
4:15 pm - 4:30 pmDiscussion
4:30 pm - 6:00 pmPoster Session
6:00 pmDinner
7:30 pm - 9:30 pmMolecular Biology Genetic Tools and Genetic Manipulation / Lipid Signaling in Parasitic Diseases
Discussion Leaders: Josh Beck (Washington University School of Medicine, USA) and Erik Allman (Pennsylvania State University, USA)
7:30 pm - 7:45 pmLauriane Sollelis (UMR MIVEGEC (CNRS 5290, IRD 224), Université de Montpellier, France)
"Unorthodox Genetic Mechanisms for Host Adaptation in Leishmania: Mosaic Aneuploidy with Flexible Gene Dosage"
7:45 pm - 7:50 pmDiscussion
7:50 pm - 8:05 pmTania Rozario (University of Illinois at Urbana-Champaign, USA)
"Characterization of the Growth and Regenerative Potential of the Rat Intestinal Tapeworm, Hymenolepis diminuta, Cultured In Vitro"
8:05 pm - 8:10 pmDiscussion
8:10 pm - 8:25 pmGeorge Wendt (University of Texas Southwestern Medical Center, USA)
"Isolation and Functional Characterization of Stem Cells from the Human Parasite Schistosoma mansoni"
8:25 pm - 8:30 pmDiscussion
8:30 pm - 8:45 pmMaurice Itoe (Harvard University, USA)
"Targeting of Lipogenic and Lipolytic Pathways in African Malaria Vectors to Control Mosquito Reproduction and P. falciparum Transmission"
8:45 pm - 8:50 pmDiscussion
8:50 pm - 9:05 pmFaiza Siddiqui (Pennsylvania State University, USA)
"Lipid Signaling Regulates Microneme Discharge and Invasion in P. falciparum Merozoites"
9:05 pm - 9:10 pmDiscussion
9:10 pm - 9:25 pmSomlata Somlata (National Institute of Infectious Diseases, Japan)
"Investigating Role of BAR Domains in Entamoeba histolytica Biology"
9:25 pm - 9:30 pmDiscussion
Sunday
7:30 am - 8:30 amBreakfast
9:00 am - 11:00 amDrug Targets and Mechanisms of Drug Resistance / Host Parasite Interactions
Discussion Leader: Dieudonne Njimoh (University of Buea, Cameroon)
9:00 am - 9:15 amMichael Thomas (University of Dundee, United Kingdom)
"The Development of DDD853651: A Potential Candidate for the Treatment of Visceral Leishmaniasis"
9:15 am - 9:20 amDiscussion
9:20 am - 9:35 amSouleymane Dama (University of Bamako, Mali)
"Exploring Mechanisms of Kelch13-Based Artemisinin Resistance in Africa"
9:35 am - 9:40 amDiscussion
9:40 am - 9:55 amVictoria Jeffers (Indiana University School of Medicine, USA)
"Disruption of Lysine Acetylation Networks in Toxoplasma gondii"
9:55 am - 10:00 amDiscussion
10:00 am - 10:15 amJerome Fru Cho (University of Buea, Cameroon)
"Molecular Typing Reveals Substantial Plasmodium vivax Infection in Asymptomatic Adults in a Rural Area of Cameroon"
10:15 am - 10:20 amDiscussion
10:20 am - 10:35 amSmriti Parashar (National Institute of Immunology, India)
"Hemoglobin Receptor Trafficking to Cell Surface Is Rab1 Independent Process in Leishmania"
10:35 am - 10:40 amDiscussion
10:40 am - 10:55 amMeilian Wang (China Medical University, China)
"Parasite Densities Modulate Susceptibility of Mice to Cerebral Malaria During Co-Infection with Schistosoma japonicum and Plasmodium berghei"
10:55 am - 11:00 amDiscussion
11:00 am - 12:30 pmPoster Session

Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pmLunch
1:30 pm - 2:30 pmMentorship Component: Career Panel Discussion
Discussion Leader: Kasturi Haldar (University of Notre Dame, USA)
1:30 pm - 1:45 pmDaniel Goldberg (Washington University School of Medicine in St. Louis, USA)
"A Career Studying Host-Parasite Interactions"
1:45 pm - 1:50 pmDiscussion
1:50 pm - 2:30 pmPanel Discussion
"Career Navigation in the Biosciences"
  • Abdoulaye Djimde (University of Science, Techniques and Technologies of Bamako, Mali)
  • Malcolm McConville (University of Melbourne, Australia)
  • Dominique Soldati-Favre (University of Geneva, Switzerland)
2:30 pm - 3:00 pmEvaluation Period
Fill in GRS Evaluation Forms
3:00 pmSeminar Concludes
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