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Neurobiology of Drug Addiction
Gordon Research Conference

Mechanistic and Translational Breakthroughs in Drug Addiction Research

Dates

July 16-21, 2017

Location

The Hong Kong University of Science and Technology
Hong Kong, China Site Information

Organizers

Chairs:
Eric J. Nestler & Yan Dong

Vice Chairs:
Yavin Shaham & Marina E. Wolf

Hong Kong Advisory Board:
Tony F. Chan, Kathryn Song Eng Cheah, Fanny M.C. Cheung, Arthur B. Ellis, Barry Halliwell, Nancy Ip, Jian Lu, Peter Mathieson, Alfonso Ngan, Paul Tam, Benjamin Wah, Henry Wong, Vivian Wing-Wah Yam, Kenneth Young & Albert Cheung-Hoi Yu More Information

Application Deadline

Applications for this meeting must be submitted by June 18, 2017. Please apply early, as some meetings become oversubscribed (full) before this deadline. If the meeting is oversubscribed, it will be stated here. Note: Applications for oversubscribed meetings will only be considered by the Conference Chair if more seats become available due to cancellations.

Meeting Description

This is the inaugural GRC on the Neurobiology of Drug Addiction, which will include investigators from a wide range of countries to discuss the latest developments in addiction research in an open and interactive format. The talks, discussions, and posters will provide ample opportunities to introduce new findings about brain mechanisms underlying compulsive drug use and relapse, as well as the application of advanced technologies for studying and manipulating brain circuitry with optogenetics, in vivo imaging, molecular approaches, and new biosensors to study addiction-related questions in humans and animal models. The program will start with two keynote talks focused on recent findings in the field as well as previews of what the future holds for addiction research. The regular presentations and discussions are categorized into eight scientific disciplines: (1) Genetic, epigenetic, and subcellular mechanisms that regulate motivated behaviors related to drug addiction. (2) Memory-oriented alterations and manipulations that are involved in the development and treatment of drug addition, such as learning, memory consolidation and reconsolidation, forgetting, and extinction learning. (3) Synaptic adaptations and manipulations in drug craving and drug seeking. (4) Brain circuits that are involved in the development and maintenance of drug-induced behaviors. (5) Novel animal models that are being crafted in addiction research. (6) Biomarkers that can be used to detect and monitor the addictive state. (7) New hypotheses of addiction that have been promoted by recent findings. (8) New techniques that promise still further advances in drug addiction research. Overall, this new GRC is designed to provide the field of drug addiction research a regular, international rendezvous to meet old and new friends, to nurture young investigators, to drive a diverse work force in the field, and to promote advances in the field toward new and definitive treatments of drug addiction.

Contributors

Meeting Program

Sunday
2:00 pm - 8:00 pmArrival and Check-in
6:00 pmDinner
7:30 pm - 7:40 pmWelcome / Introductory Comments by GRC Site Staff
7:40 pm - 9:30 pmKeynote Session: The Future of Addiction Research
Discussion Leader: Barbara Mason (The Scripps Research Institute, USA)
7:40 pm - 8:25 pmNora Volkow (National Institute on Drug Abuse, NIH, USA)
"The Future of Addiction Research and Treatment"
8:25 pm - 8:35 pmDiscussion
8:35 pm - 9:20 pmPier Vincenzo Piazza (Neurocentre Magendie, INSERM U1215, France)
"From Basic Preclinical Discoveries to New Addiction Treatments"
9:20 pm - 9:30 pmDiscussion
Monday
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmEpigenetic and Cellular Mechanisms of Drug Addiction
Discussion Leader: Chris Pierce (University of Pennsylvania, USA)
9:00 am - 9:25 amPaul Kenny (Icahn School of Medicine at Mount Sinai, USA)
"Epigenetic and Cellular Mechanisms of Cocaine Dependence"
9:25 am - 9:35 amDiscussion
9:35 am - 10:00 amCourtney Miller (Scripps Research Institute, USA)
"Epigenetic and Synaptic Mechanisms in Methamphetamine Dependence"
10:00 am - 10:10 amDiscussion
10:10 am - 10:40 amGroup Photo / Coffee Break
10:40 am - 11:05 amDorit Ron (University of California, San Francisco, USA)
"Molecular Mechanisms Underlying Alcohol Abuse Disorders"
11:05 am - 11:15 amDiscussion
11:15 am - 11:40 amYasmin Hurd (Icahn School of Medicine at Mount Sinai, USA)
"Epigenetic Effects of Cannabis Exposure"
11:40 am - 11:50 amDiscussion
11:50 am - 12:05 pmShort Talk Selected from Poster Abstracts
12:05 pm - 12:10 pmDiscussion
12:10 pm - 12:25 pmShort Talk Selected from Poster Abstracts
12:25 pm - 12:30 pmDiscussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session
6:00 pmDinner
7:30 pm - 9:30 pmLearning Mechanisms of Drug Addiction
Discussion Leader: Jian-Guo Chen (Huazhong University of Science and Technology, China)
7:30 pm - 7:55 pmKaren Ersche (University of Cambridge, United Kingdom)
"From Habits to Addiction: A Slippery Slope?"
7:55 pm - 8:05 pmDiscussion
8:05 pm - 8:30 pmShannon Gourley (Emory University School of Medicine, USA)
"Induction and Blockade of Cocaine-Induced Habits"
8:30 pm - 8:40 pmDiscussion
8:40 pm - 9:05 pmJoseph Cheer (University of Maryland School of Medicine, USA)
"Probing the Role of Endocannabinoids in Dopaminergic Encoding of Reinforcement Learning"
9:05 pm - 9:15 pmDiscussion
9:15 pm - 9:25 pmShort Talk Selected from Poster Abstracts
9:25 pm - 9:30 pmDiscussion
Tuesday
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmSynaptic Mechanisms of Drug Addiction
Discussion Leader: Julie Kauer (Brown University, USA)
9:00 am - 9:35 amYanhua Huang (University of Pittsburgh, USA)
"Silent Synapses and Cocaine Addiction"
9:35 am - 9:50 amDiscussion
9:50 am - 10:25 amElena Bagley (University of Sydney, Australia)
"Synaptic Mechanism of Opiate Addiction"
10:25 am - 10:40 amDiscussion
10:40 am - 11:10 amCoffee Break
11:10 am - 11:45 amChristian Lüscher (University of Geneva, Switzerland)
"Corticostriatal Circuits, Synaptic Plasticity, and Drug Addiction"
11:45 am - 12:00 pmDiscussion
12:00 pm - 12:10 pmShort Talk Selected from Poster Abstracts
12:10 pm - 12:15 pmDiscussion
12:15 pm - 12:25 pmShort Talk Selected from Poster Abstracts
12:25 pm - 12:30 pmDiscussion
12:30 pmLunch
2:00 pm - 4:00 pmPoster Session
4:00 pm - 6:00 pmCircuitry of Drug Addiction
Discussion Leader: Marina Picciotto (Yale University, USA)
4:00 pm - 4:25 pmGavan McNally (University of New South Wales, Australia)
"Ventral Striatal and Pallidal Output Pathways Promoting Versus Preventing Relapse"
4:25 pm - 4:30 pmDiscussion
4:30 pm - 4:55 pmPeter Kalivas (University of South Carolina School of Medicine, USA)
"Tetrapartite Synapses and Accumbens Microcircuitry in Relapse"
4:55 pm - 5:00 pmDiscussion
5:00 pm - 5:25 pmVeronica Alvarez (National Institute on Alcohol Abuse and Alcoholism, NIH, USA)
"Striatal Circuits and Mechanisms Mediating Behavioral Responses to Addictive Drugs"
5:25 pm - 5:30 pmDiscussion
5:30 pm - 5:55 pmMarisela Morales (National Institute on Drug Abuse Intramural Research Program, NIH, USA)
"Role of VTA Glutamate Neurons in Drug Reward and Aversion"
5:55 pm - 6:00 pmDiscussion
6:00 pmDinner
Wednesday
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmNovel Animal Models of Drug Addiction and Relapse
Discussion Leader: Aldo Badiani (University of Sussex, United Kingdom)
9:00 am - 9:35 amLin Lu (Peking University Sixth Hospital, China)
"Novel UCS-Based Retrieval-Reconsolidation Procedures for Relapse Prevention"
9:35 am - 9:50 amDiscussion
9:50 am - 10:25 amSerge Ahmed (CNRS, France)
"Animal Models of Drug Choice: Role of OFC"
10:25 am - 10:40 amDiscussion
10:40 am - 11:10 amCoffee Break
11:10 am - 11:45 amVeronque Deroche-Gamonet (Neurocentre Magendie, INSERM U1215, France)
"The 3 Criteria Addiction Model: From Behavior to Cellular Mechanisms"
11:45 am - 12:00 pmDiscussion
12:00 pm - 12:10 pmShort Talk Selected from Poster Abstracts
12:10 pm - 12:15 pmDiscussion
12:15 pm - 12:25 pmShort Talk Selected from Poster Abstracts
12:25 pm - 12:30 pmDiscussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session
6:00 pmDinner
7:00 pm - 7:30 pmBusiness Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
7:30 pm - 9:30 pmBiomarkers for Translational Research in Drug Addiction
Discussion Leader: Lan Ma (Fudan University, China)
7:30 pm - 7:55 pmRita Goldstein (Icahn School of Medicine at Mount Sinai, USA)
"Cortical Mechanisms of Drug Addiction in Humans"
7:55 pm - 8:05 pmDiscussion
8:05 pm - 8:30 pmRajita Sinha (Yale University School of Medicine, USA)
"Stress and Relapse in Humans: Genetics, Pharmacology, and Brain Imaging"
8:30 pm - 8:40 pmDiscussion
8:40 pm - 9:05 pmMarkus Heilig (Linkoping University, Sweden)
"What Does Personalized Medicine Mean in Alcohol Addiction?"
9:05 pm - 9:15 pmDiscussion
9:15 pm - 9:25 pmShort Talk Selected from Poster Abstracts
9:25 pm - 9:30 pmDiscussion
Thursday
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmAdvances in Addiction Theory
Discussion Leader: Harriet de Wit (University of Chicago, USA)
9:00 am - 9:35 amGeorge Koob (National Institute on Alcohol Abuse and Alcoholism, NIH, USA)
"Negative Reinforcement Based Addiction Models: Past, Present, and Future"
9:35 am - 9:50 amDiscussion
9:50 am - 10:25 amTerry Robinson (University of Michigan, USA)
"Incentive-Sensitization and Addiction: Recent Preclinical Studies"
10:25 am - 10:40 amDiscussion
10:40 am - 11:10 amCoffee Break
11:10 am - 11:45 amDavid Belin (University of Cambridge, United Kingdom)
"The Psychological and Neural Basis of Incentive Habits: Relevance for Our Understanding of Addiction"
11:45 am - 12:00 pmDiscussion
12:00 pm - 12:10 pmShort Talk Selected from Poster Abstracts
12:10 pm - 12:15 pmDiscussion
12:15 pm - 12:25 pmShort Talk Selected from Poster Abstracts
12:25 pm - 12:30 pmDiscussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmCutting-Edge Basic and Clinical Addiction Research
Discussion Leader: Taco De Vries (VU University Medical Center, The Netherlands)
4:00 pm - 4:25 pmBruce Hope (National Institute on Drug Abuse, NIH, USA)
"Role of Corticostriatal Neuronal Ensembles in Conditioned Drug Effects and Drug Relapse"
4:25 pm - 4:35 pmDiscussion
4:35 pm - 5:00 pmAbraham Zangen (Ben-Gurion University of the Negev, Israel)
"H-Coil TMS: A Novel Treatment of Drug Addiction"
5:00 pm - 5:10 pmDiscussion
5:10 pm - 5:35 pmRobert Malenka (Stanford University School of Medicine, USA)
"Rabies Virus-Based Screening of Circuit Changes Following Drug Administration"
5:35 pm - 5:45 pmDiscussion
5:45 pm - 5:55 pmShort Talk Selected from Poster Abstracts
5:55 pm - 6:00 pmDiscussion
6:00 pmDinner
Friday
7:30 am - 8:30 amBreakfast
9:00 amDeparture
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