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Bioorganic Chemistry (GRS)
Gordon-Kenan Research Seminar

Understanding Biological Systems Through Chemical Approaches

Dates

June 10-11, 2017

Location

Proctor Academy
Andover, NH Site Information

Organizers

Chairs:
Clifford T. Gee & Ashley Modell

Application Deadline

Applications for this meeting must be submitted by May 13, 2017. Please apply early, as some meetings become oversubscribed (full) before this deadline. If the meeting is oversubscribed, it will be stated here. Note: Applications for oversubscribed meetings will only be considered by the Conference Chair if more seats become available due to cancellations.

GRS Speaker Abstract Deadline: Although applications will be accepted until the date noted above, any applicants who wish to be considered for an oral presentation should submit their application by March 10, 2017. Please refer to the application instructions in the Meeting Description section below for more details (if available).

Meeting Description

Overview

The Gordon Research Seminar on Bioorganic Chemistry is a unique forum for graduate students, post-docs, and other scientists with comparable levels of experience and education to present and exchange new data and cutting edge ideas.

The first Gordon Research Seminar in Bioorganic Chemistry (featuring Peter Schultz as the keynote speaker) will focus on chemical approaches to answering some of biology's biggest questions while providing graduate students and postdocs the opportunity to become acquainted with their peers prior to the GRC, to share and listen to cutting-edge research, and to network with each other.

Application Instructions

The meeting will feature approximately 10 talks and 2 poster sessions. All attendees are expected to actively participate in the GRS either by giving an oral presentation or presenting a poster. Therefore, all applications must include an abstract.

The Chairs will select speakers from abstracts submitted by March 10, 2017. Those applicants who are not chosen for talks and those who apply after the deadline to be considered for an oral presentation will be expected to present a poster. In order to participate, you must submit an application by the date indicated in the Application Deadline section above.

Related Meeting

This GRS will be held in conjunction with the "Bioorganic Chemistry" Gordon Research Conference (GRC). Those interested in attending both meetings must submit an application for the GRC in addition to an application for the GRS. Refer to the associated GRC program page for more information.

Contributors

Meeting Program

Saturday
2:00 pm - 5:00 pmArrival and Check-in
3:30 pm - 3:45 pmIntroductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair
3:45 pm - 4:30 pmKeynote Session: An Expanding Genetic Code
Discussion Leaders: Kristen DeMeester (University of Delaware, USA) and Tyler Bechtel (Boston College, USA)
3:45 pm - 4:15 pmPeter Schultz (The Scripps Research Institute, USA)
"An Expanding Genetic Code"
4:15 pm - 4:30 pmDiscussion
4:30 pm - 6:00 pmPoster Session
6:00 pmDinner
7:30 pm - 9:30 pmProteomics and Permutations: Molecular Activity in Biology
Discussion Leaders: Kalie Mix (University of Wisconsin-Madison, USA) and James Poland (Vanderbilt University, USA)
7:30 pm - 7:50 pmChristine Kaiser (AstraZeneca, USA)
"Small-Molecule Modulation of Antibody Structure and Function"
7:50 pm - 8:00 pmDiscussion
8:00 pm - 8:20 pmXiaochuan Cai (Chemical Biology Program, Memorial Sloan Kettering Cancer Center, USA)
"Inhibitors of Protein Methyltransferases as Epigenetic Modulators in Chemical Biology and Medicine"
8:20 pm - 8:30 pmDiscussion
8:30 pm - 8:50 pmChristopher Parker (The Scripps Research Institute, USA)
"Expanding the Ligandable Proteome: Ligand and Target Discovery by Fragment-Based Screening in Cells"
8:50 pm - 9:00 pmDiscussion
9:00 pm - 9:20 pmRhushikesh Kulkarni (National Cancer Institute, NIH, USA)
"Chemoproteomic Portrait of the Oncometabolite Fumarate"
9:20 pm - 9:30 pmDiscussion
Sunday
7:30 am - 8:30 amBreakfast
9:00 am - 11:00 amRecognition and Reporting: Reading Biology Through the Lens of Chemistry
Discussion Leaders: Mia Huang (University of California, San Diego, USA) and Siddharth Matikonda (University of Otago, New Zealand)
9:00 am - 9:20 amAntoinette Blom (California Institute of Technology, USA)
"Probing Drug Binding Interactions in Receptors of the Central Nervous System"
9:20 am - 9:30 amDiscussion
9:30 am - 9:50 amJoshua Yim (Stanford University School of Medicine, USA)
"Developing Optical Chemical Probes for Imaging Proteolytic Signatures"
9:50 am - 10:00 amDiscussion
10:00 am - 10:20 amBrittany Morgan (Duke University, USA)
"Design, Synthesis and Evaluation of Small Molecule Libraries for the Selective Recognition of Therapeutically Relevant RNA"
10:20 am - 10:30 amDiscussion
10:30 am - 10:50 amNeena Pyzocha (Broad Institute of MIT and Harvard, USA)
"Discovery and Biochemical Characterization of Cas13b, a CRISPR-Associated RNase"
10:50 am - 11:00 amDiscussion
11:00 am - 12:30 pmPoster Session

Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pmLunch
1:30 pm - 2:30 pmMentorship Component: Career Panel
Discussion Leader: Zachary Hill (University of California, San Francisco, USA)
1:30 pm - 2:30 pmPanel Discussion
"Leaving the Bench: Non-Traditional Careers for Bioorganic Chemists"
  • Charles Cabral (Federal Bureau of Investigation, USA)
  • Bethany Halford (Chemical and Engineering News, USA)
  • Erik Spek (Vedanta Biosciences, Inc., USA)
  • James Stover (Aegis Sciences Corporation, USA)
2:30 pm - 3:00 pmEvaluation Period
Fill in GRS Evaluation Forms
3:00 pmSeminar Concludes
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