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Bioorganic Chemistry (GRS)
Gordon-Kenan Research Seminar

Understanding Biological Systems Through Chemical Approaches

Dates

June 10-11, 2017

Location

Proctor Academy
Andover, NH

Organizers

Chairs:
Clifford T. Gee & Ashley Modell

Meeting Description

The Gordon Research Seminar on Bioorganic Chemistry is a unique forum for graduate students, post-docs, and other scientists with comparable levels of experience and education to present and exchange new data and cutting edge ideas.

The first Gordon Research Seminar in Bioorganic Chemistry (featuring Peter Schultz as the keynote speaker) will focus on chemical approaches to answering some of biology's biggest questions while providing graduate students and postdocs the opportunity to become acquainted with their peers prior to the GRC, to share and listen to cutting-edge research, and to network with each other.

Related Meeting

This GRS was held in conjunction with the "Bioorganic Chemistry" Gordon Research Conference (GRC). Refer to the associated GRC program page for more information.

Contributors

Meeting Program

Saturday
2:00 pm - 5:00 pmArrival and Check-in
3:30 pm - 3:45 pmIntroductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair
3:45 pm - 4:30 pmKeynote Session: An Expanding Genetic Code
Discussion Leaders: Kristen DeMeester (University of Delaware, USA) and Tyler Bechtel (Boston College, USA)
3:45 pm - 4:15 pmPeter Schultz (The Scripps Research Institute, USA)
"An Expanding Genetic Code"
4:15 pm - 4:30 pmDiscussion
4:30 pm - 6:00 pmPoster Session
6:00 pmDinner
7:30 pm - 9:30 pmProteomics and Permutations: Molecular Activity in Biology
Discussion Leaders: Kalie Mix (University of Wisconsin-Madison, USA) and Rumit Maini (The University of Tokyo, Japan)
7:30 pm - 7:50 pmChristine Kaiser (AstraZeneca, USA)
"Small-Molecule Modulation of Antibody Structure and Function"
7:50 pm - 8:00 pmDiscussion
8:00 pm - 8:20 pmXiaochuan Cai (Chemical Biology Program, Memorial Sloan Kettering Cancer Center, USA)
"Inhibitors of Protein Methyltransferases as Epigenetic Modulators in Chemical Biology and Medicine"
8:20 pm - 8:30 pmDiscussion
8:30 pm - 8:50 pmChristopher Parker (The Scripps Research Institute, USA)
"Expanding the Ligandable Proteome: Ligand and Target Discovery by Fragment-Based Screening in Cells"
8:50 pm - 9:00 pmDiscussion
9:00 pm - 9:20 pmRhushikesh Kulkarni (National Cancer Institute, NIH, USA)
"Chemoproteomic Portrait of the Oncometabolite Fumarate"
9:20 pm - 9:30 pmDiscussion
Sunday
7:30 am - 8:30 amBreakfast
9:00 am - 11:00 amRecognition and Reporting: Reading Biology Through the Lens of Chemistry
Discussion Leaders: Mia Huang (University of California, San Diego, USA) and Siddharth Matikonda (University of Otago, New Zealand)
9:00 am - 9:20 amAntoinette Blom (California Institute of Technology, USA)
"Probing Drug Binding Interactions in Receptors of the Central Nervous System"
9:20 am - 9:30 amDiscussion
9:30 am - 9:50 amJoshua Yim (Stanford University School of Medicine, USA)
"Developing Optical Chemical Probes for Imaging Proteolytic Signatures"
9:50 am - 10:00 amDiscussion
10:00 am - 10:20 amBrittany Morgan (Duke University, USA)
"Design, Synthesis and Evaluation of Small Molecule Libraries for the Selective Recognition of Therapeutically Relevant RNA"
10:20 am - 10:30 amDiscussion
10:30 am - 10:50 amNeena Pyzocha (Broad Institute of MIT and Harvard, USA)
"Discovery and Biochemical Characterization of Cas13b, a CRISPR-Associated RNase"
10:50 am - 11:00 amDiscussion
11:00 am - 12:30 pmPoster Session

Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pmLunch
1:30 pm - 2:30 pmMentorship Component: Career Panel
Discussion Leader: Zachary Hill (University of California, San Francisco, USA)
1:30 pm - 2:30 pmPanel Discussion
"Leaving the Bench: Non-Traditional Careers for Bioorganic Chemists"
  • Charles Cabral (Federal Bureau of Investigation, USA)
  • Bethany Halford (Chemical and Engineering News, USA)
  • Erik Spek (Vedanta Biosciences, USA)
  • James Stover (Aegis Sciences Corporation, USA)
2:30 pm - 3:00 pmEvaluation Period
Fill in GRS Evaluation Forms
3:00 pmSeminar Concludes
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