The Gordon Research Seminar on Translation Machinery in Health and Disease is a unique forum for graduate students, post-docs, and other scientists with comparable levels of experience and education to present and exchange new data and cutting edge ideas.
The focus of this meeting is to provide fundamental mechanistic insights on the role the translation machinery plays in physiological and pathogenic scenarios. Topics covered by an interdisciplinary selection of speakers will include: the use of systems biology and large dataset analyses to study gene translation at transcriptomics and proteomics scale, the description of novel non-canonical functions of the components of the translation machinery, and the emerging roles of post-transcriptional RNA modifications.
This GRS was held in conjunction with the "Translation Machinery in Health & Disease" Gordon Research Conference (GRC)
. Refer to the associated GRC program page
for more information.
|2:00 pm - 5:00 pm||Arrival and Check-in|
|3:30 pm - 3:45 pm||Introductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair|
|3:45 pm - 4:30 pm||Keynote Session: Beyond the Canonical View of Protein Translation|
|Discussion Leader: Adrian Torres (Institute for Research in Biomedicine (IRB Barcelona), Spain)|
|3:45 pm - 4:20 pm||Christine Mayr (Memorial Sloan Kettering Cancer Center, USA)|
"New Insights into 3'UTR-Mediated Protein-Protein Interactions"
|4:20 pm - 4:30 pm||Discussion|
|4:30 pm - 6:00 pm||Poster Session|
|7:30 pm - 9:30 pm||RNA Modifications, Ribosomes and Disease|
|Discussion Leader: Mary Anne Rubio (The Ohio State University, USA)|
|7:30 pm - 7:50 pm||Markus Schosserer (University of Natural Resources and Life Sciences, Vienna, Austria)|
"Characterization of Ribosomal RNA Base Methylations Modulating Life and Healthspan"
|7:50 pm - 8:00 pm||Discussion|
|8:00 pm - 8:20 pm||Elif Sarinay Cenik (Stanford University, USA)|
"Molecular Modeling of Systemic Effects of Ribosomal Protein Imbalance"
|8:20 pm - 8:30 pm||Discussion|
|8:30 pm - 8:50 pm||Jean-Denis Beaudoin (Yale University, USA)|
"Ribosomes Sculpt mRNA Structure During Embryogenesis"
|8:50 pm - 9:00 pm||Discussion|
|9:00 pm - 9:20 pm||Tara Peters (University of Miami, USA)|
"Preclinical Assessment of Elatol as a Novel eIF4A Inhibitor for Cancer Therapeutics"
|9:20 pm - 9:30 pm||Discussion|
|7:30 am - 8:30 am||Breakfast|
|9:00 am - 11:00 am||Translational Control|
|Discussion Leader: Jean-Denis Beaudoin (Yale University, USA)|
|9:00 am - 9:20 am||Nathaniel Robichaud (McGill University, Canada)|
"Translational Control of the Tumour Microenvironment"
|9:20 am - 9:30 am||Discussion|
|9:30 am - 9:50 am||Seungjae Jeong (Seoul National University, South Korea)|
"Human Threonyl-tRNA Synthetase Controls Translation Initiation via Specific Interaction with eIF4E Homologous Protein"
|9:50 am - 10:00 am||Discussion|
|10:00 am - 10:20 am||Kyle Mohler (The Ohio State University, USA)|
"Editing of Misaminoacylated tRNA Controls the Sensitivity of Amino Acid Stress Responses in Saccharomyces cerevisiae"
|10:20 am - 10:30 am||Discussion|
|10:30 am - 10:50 am||Erin Kennedy (University of Ottawa, Canada)|
"Using Yeast to Study the Pathobiology of SIFD"
|10:50 am - 11:00 am||Discussion|
|11:00 am - 12:30 pm||Poster Session|
|Coffee will be served in the poster area from 11:00 am - 11:30 am|
|1:30 pm - 2:30 pm||Mentorship Component: How
to Succeed in Science?|
|Discussion Leader: Eva Maria Novoa (Garvan Institute of Medical Research, Australia)|
|1:30 pm - 2:15 pm||Jonathan Yewdell (National Institutes of Health, USA)|
"How to Succeed in Science Without Really Trying"
|2:15 pm - 2:30 pm||Discussion|
|2:30 pm - 3:00 pm||Evaluation Period|
|Fill in GRS Evaluation Forms|
|3:00 pm||Seminar Concludes|